Search of ligands suitable for 212Pb/212Bi in vivo generators

Journal of Radioanalytical and Nuclear Chemistry

Volumn 295, Issue 1, 2013, Pages 205-209

  Bartoś, Barbara ^a   Lyczko, Krzysztof ^a   Kasperek, Agata ^a   Krajewski, Seweryn ^a   Bilewicz, Aleksander ^a  

^a INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

Author keywords

212Bi; 212Pb; In vivo generator; Polyaminipolycarboxylate ligands

Indexed keywords

BISMUTH 212; CATION; DIOCTYL TEREPHTHALATE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; LEAD 212; LIGAND; POLYDENTATE LIGAND; SODIUM CHLORIDE; TETRAXETAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; GENERATOR; HALF LIFE TIME; IN VIVO GENERATOR; ISOTOPE LABELING; LIMIT OF DETECTION; MOLECULAR STABILITY; RADIOACTIVITY;

EID: 84871919004     PISSN: 02365731     EISSN: 15882780     Source Type: Journal    
DOI: 10.1007/s10967-012-2238-4     Document Type: Article

References (14)

1. Hall EJ (1988) Radiobiology for the radiologist. Lippincott, Philadelphia, pp 161-177
2. Humm JL, Cobb LM (1990) Nonuniformity of tumor dose in radioimmunotherapy. J Nucl Med 31:75-83
3. Zalutsky MR, Pozzi OR (2004) Radioimmunotherapy with α-particle emitting radionuclides. Q J Nucl Med 48:1-7
4. 213Bi-DOTA-[Thi8, Met(O2)11]-substance P: a pilot trial. Eur J Nucl Med Mol Imaging 37:1335-1344
5. 211At-labeled monoclonal antibodies. Nucl Med Biol 34:779-785
6. 212Pb as a clinical therapeutic; getting the lead in! Dalton Trans 40:6068
7. Leichner PK (1996) Radiation dosimetry of monoclonal antibodies: practical considerations. In: Henkin RE, Boles MA, Dillehay GL, Halama JR, Karesh SM, Wagner RH, Zimmer AM (eds) Nuclear Medicine. St Louis, Mosby, pp 558-562
8. Henriksen G, Schoultz BW, Hoff P, Larsen RH (2003) Potential in vivo generator for alpha-particle therapy with Bi-212: presentation of a system to minimize escape of daughter nuclide after decay of Pb-212 to Bi-212. Radiochim Acta 91:109-113
9. 2- complex. Radiochim Acta 60:1-10
10. Milenic DE, Garmestani K, Brady ED, Albert PS, Ma DS, Abdulla A, Brechbiel MW (2005) Alpha-particle radioimmunotherapy of disseminated peritoneal disease using a Pb-212-labeled radioimmunoconjugate targeting HER2. Cancer Biother Radiopharm 20:557-568
11. Zhang X, Gallazzi F, Quinn T, Deutschera S (2010) Pb-212-labeled α-MSH analogue modified with a nuclear localization sequence for melanoma targeting. Nucl Med Biol 37:693
12. Milenic DE, Garmestani K, Brady ED, Baidoo KE, Albert PS, Wong K, Flynn J, Brechbiel MW (2008) Multimodality therapy: potentiation of high-LET radiation with paclitaxel for the treatment of disseminated peritoneal disease. Clin Cancer Res 14:5108-5115
13. Miao Y, Hylarides M, Fisher DR, Shelton T, Moore H, Wester DW, Fritzberg AR, Winkelmann CT, Hoffman T, Quinn TP (2005) Melanoma therapy via peptide targeted alpha-radiation. Clin Cancer Res 11:5616-5621
14. 212Bi generator. Nucl Med Biol 32:741-747