A beveled working electrode coupled to a sandglass shape detection cell: A strategy to improve the sensitivity of electrochemiluminescence detection in microchip electrophoresis

Electrochimica Acta

Volumn 90, Issue , 2013, Pages 101-107

  Pan, Jianbin ^a   Li, Xinchun ^a,b   Chen, Zuanguang ^a   Yang, Fan ^a,c   Wu, Xiaohang ^a   Li, Yinbao ^a   Sun, Duanping ^a   Yu, Yanyan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

^c SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

Author keywords

Beveled electrode; Electrochemiluminescence; Electrophoresis; Microchip; Tris(2,2 bipyridyl) ruthenium(II)

Indexed keywords

BIPYRIDYL; BOTTOM LAYERS; COUNTER ELECTRODES; DETECTION CELLS; DETECTION SENSITIVITY; DISK ELECTRODE; ELECTROCHEMILUMINESCENCE; ELECTROCHEMILUMINESCENCE DETECTION; GLASS PLATE; GLASS WAFER; GUIDE TUBES; INJECTION CHANNELS; INVERTED FUNNEL; LIMIT OF DETECTION; MELT ADHESIVES; MICRO-DEVICE; MICROCHIP; MICROCHIP CAPILLARY ELECTROPHORESIS; MICROCHIP ELECTROPHORESIS; MIDDLE LAYER; PLASMA CLEANERS; POLYDIMETHYLSILOXANE PDMS; SEPARATION CHANNEL; SHAPE DETECTION; THREE-LAYER; TOP LAYERS; WORKING ELECTRODE;

CAPILLARY ELECTROPHORESIS; DRILLS; ELECTROPHORESIS; EPOXY RESINS; GLASS; MICROCHANNELS; PLATINUM; RUTHENIUM; SEPARATION; SILICONES; TUBES (COMPONENTS); WIRE;

MICROPROCESSOR CHIPS;

EID: 84871902906     PISSN: 00134686     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.electacta.2012.11.118     Document Type: Article

References (45)

1. N.E. Tokel, and A.J. Bard Electrogenerated chemiluminescence. IX. Electrochemistry and emission from systems containing tris(2,2'-bipyridine) ruthenium(II) dichloride Journal of the American Chemical Society 94 1972 2862
2. H. Yang, X.C. Li, F. Yang, J. Feng, M.Y. Lin, and Z.G. Chen Electrochemiluminescence detection system for microchip capillary electrophoresis and its application to pharmaceutical analysis Microchimica Acta 175 2011 193
3. D.R. Zhu, X. Li, J.Y. Sun, and T.Y. You Chemometrics optimization of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection Talanta 88 2012 265
4. Y.L. Yuan, H.J. Li, S.A. Han, L.Z. Hu, and G.B. Xu Application of cement as new electrode material and solid-phase microextraction material demonstrated by electrochemiluminescent detection of perphenazine Talanta 84 2011 49
5. Y. Zhang, S.G. Ge, S.W. Wang, M. Yan, J.H. Yu, X.R. Song, and W.Y. Liu Magnetic beads-based electrochemiluminescence immunosensor for determination of cancer markers using quantum dot functionalized PtRu alloys as labels Analyst 137 2012 2176
6. N.P. Sardesai, J.C. Barron, and J.F. Rusling Carbon nanotube microwell array for sensitive electrochemiluminescent detection of cancer biomarker proteins Analytical Chemistry 83 2011 6698
7. R. Kurita, K. Arai, K. Nakamoto, D. Kato, and O. Niwa Determination of DNA methylation using electrochemiluminescence with surface accumulable coreactant Analytical Chemistry 84 2012 1799
8. Q.X. Sun, G.Z. Zou, and X.L. Zhang Electrochemiluminescence DNA sensor based on hairpin structure DNA as recognition element and Ru(bpy)(3)(2+)-doped silica nanoparticles as signal-producing compound Electroanalysis 23 2011 2693
9. T. Yuan, Z.Y. Liu, L.Z. Hu, L. Zhang, and G.B. Xu Label-free supersandwich electrochemiluminescence assay for detection of sub-nanomolar Hg(2+) Chemical Communications 47 2011 11951
10. M. Zhang, S.G. Ge, W.P. Li, M. Yan, X.R. Song, J.H. Yu, W. Xu, and J.D. Huang Ultrasensitive electrochemiluminescence immunoassay for tumor marker detection using functionalized Ru-silica@nanoporous gold composite as labels Analyst 137 2012 680
11. J. Qian, Z.X. Zhou, X.D. Cao, and S.Q. Liu Electrochemiluminescence immunosensor for ultrasensitive detection of biomarker using Ru(bpy)(3)(2+)-encapsulated silica nanosphere labels Analytica Chimica Acta 665 2010 32
12. W.J. Miao Electrogenerated chemiluminescence and its biorelated applications Chemical Reviews 108 2008 2506
13. J. Li, S.J. Guo, and E.K. Wang Recent advances in new luminescent nanomaterials for electrochemiluminescence sensors RSC Advances 2 2012 3579
14. M. Zhang, W.J. Dai, M. Yan, S.G. Ge, J.H. Yu, X.R. Song, and W. Xu Ultrasensitive electrochemiluminescence immunosensor using PtAg@carbon nanocrystals composites as labels and carbon nanotubes-chitosan/gold nanoparticles as enhancer Analyst 137 2012 2112
15. M.M. Richter Electrochemiluminescence (ECL) Chemical Reviews 104 2004 3003
16. A. Manz Sens. miniaturrized total chemical analysis:a novel concept for chemical sensing Sensors and Actuators B-Chemical 1 1990 244
17. D.J. Harrison, K. Fluri, K. Seiler, Z. Fan, C.S. Effenhauser, and A. Manz Micromachining a miniaturized capillary electrophoresis-based chemical analysis system on a chip Science 261 1993 895
18. A. Arora, G. Simone, G.B. Salieb-Beugelaar, J.T. Kim, and A. Manz Latest developments in micro total analysis systems Analytical Chemistry 82 2010 4830
19. F. Yang, X.C. Li, W. Zhang, J.B. Pan, and Z.G. Chen A facile light-emitting-diode induced fluorescence detector coupled to an integrated microfluidic device for microchip electrophoresis Talanta 84 2011 1099
20. Y. Du, and E. Wang Separation and detection of narcotic drugs on a microchip using micellar electrokinetic chromatography and electrochemiluminescence Electroanalysis 20 2008 643
21. X.C. Li, J.B. Pan, F. Yang, J. Feng, J.Y. Mo, and Z.G. Chen Simple amperometric detector for microchip capillary electrophoresis, and its application to the analysis of dopamine and catechol Microchimica Acta 174 2011 123
22. X.C. Li, Z.G. Chen, Y.W. Zhong, F. Yang, J.B. Pan, and Y.J. Liang Cobalt hexacyanoferrate modified multi-walled carbon nanotubes/graphite composite electrode as electrochemical sensor on microfluidic chip Analytica Chimica Acta 710 2012 118
23. M. Hervas, M.A. Lopez, and A. Escarpa Electrochemical microfluidic chips coupled to magnetic bead-based ELISA to control allowable levels of zearalenone in baby foods using simplified calibration Analyst 134 2009 2405
24. L. Yang, and R. Bashir Electrical/electrochemical impedance for rapid detection of foodborne pathogenic bacteria Biotechnology Advances 26 2008 135
25. J.C. Jokerst, J.M. Emory, and C.S. Henry Advances in microfluidics for environmental analysis Analyst 137 2012 24
26. S.E. Weigum, P.N. Floriano, N. Christodoulides, and J.T. McDevitt Cell-based sensor for analysis of EGFR biomarker expression in oral cancer Lab on a Chip 7 2007 995
27. B.L. Ziober, M.G. Mauk, E.M. Falls, Z. Chen, A.F. Ziober, and H.H. Bau Lab-on-a-chip for oral cancer screening and diagnosis Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 30 2008 111
28. F.J. Shang, E. Guihen, and J.D. Glennon Recent advances in miniaturisation-the role of microchip electrophoresis in clinical analysis Electrophoresis 33 2012 105
29. S. Cho, D.K. Kang, J. Choo, A.J. deMello, and S.I. Chang Recent advances in microfluidic technologies for biochemistry and molecular biology BMB Reports 44 2011 705
30. A.J. Hopwood, C. Hurth, J.N. Yang, Z. Cai, N. Moran, J.G. Lee-Edghill, A. Nordquist, R. Lenigk, M.D. Estes, J.P. Haley, C.R. McAlister, X. Chen, C. Brooks, S. Smith, K. Elliott, P. Koumi, F. Zenhausern, and G. Tully Integrated microfluidic system for rapid forensic DNA analysis: sample collection to DNA profile Analytical Chemistry 82 2010 6991
31. E. Verpoorte Microfluidic chips for clinical and forensic analysis Electrophoresis 23 2002 677
32. Y. Du, and E.K. Wang Capillary electrophoresis and microchip capillary electrophoresis with electrochemical and electrochemiluminescence detection Journal of Separation Science 30 2007 875
33. H.B. Qiu, X.B. Yin, J.L. Yan, X.C. Zhao, X.R. Yang, and E.K. Wang Simultaneous electrochemical and electrochemiluminescence detection for microchip and conventional capillary electrophoresis Electrophoresis 26 2005 687
34. A. Arora, J.C.T. Eijkel, W.E. Morf, and A. Manz A wireless electrochemiluminescence detector applied to direct and indirect detection for electrophoresis on a microfabricated glass device Analytical Chemistry 73 2001 3282
35. F. Mavre, K.-F. Chow, E. Sheridan, B.-Y. Chang, J.A. Crooks, and R.M. Crooks A Theoretical and experimental framework for understanding electrogenerated chemiluminescence (ECL) emission at bipolar electrodes Analytical Chemistry 81 2009 6218
36. F. Mavre, R.K. Anand, D.R. Laws, K.-F. Chow, B.-Y. Chang, J.A. Crooks, and R.M. Crooks Bipolar electrodes: a useful tool for concentration, separation, and detection of analytes in microelectrochemical systems Analytical Chemistry 82 2010 8766
37. H.B. Qiu, J.L. Yan, X.H. Sun, J.F. Liu, W.D. Cao, X.R. Yang, and E.K. Wang Microchip capillary electrophoresis with an integrated indium tin oxide electrode-based electrochemiluminescence detector Analytical Chemistry 75 2003 5435
38. S.N. Ding, J.J. Xu, and H.Y. Chen Microchip capillary electrophoresis coupled with an end-column electrochemiluminescence detection Talanta 70 2006 403
39. Y. Du, H. Wei, J. Kang, J. Yan, X.-b. Yin, X. Yang, and E. Wang Microchip capillary electrophoresis with solid-state electrochemiluminescence detector Analytical Chemistry 77 2005 7993
40. J.K. Leland, and M.J. Powell Electrogenerated chemiluminescence: an oxidative-reduction type ECL reaction sequence using tripropyl amine Journal of the Electrochemical Society 137 1990 3127
41. J.B. Noffsinger, and N.D. Danielson Generation of chemiluminescence upon reaction of aliphatic amines with tris(2,2'-bipyridine)ruthenium(III) Analytical Chemistry 59 1987 865
42. Y. Zu, and A.J. Bard Electrogenerated chemiluminescence. 66. The role of direct coreactant oxidation in the ruthenium Tris(2,2')bipyridyl/tripropylamine system and the effect of halide ions on the emission intensity Analytical Chemistry 72 2000 3223
43. J.G. Li, Y. Chun, and H.X. Ju Simultaneous electrochemiluminescence detection of anisodamine, atropine, and scopolamine in Flos daturae by capillary electrophoresis using beta-Cyclodextrin as additive Electroanalysis 19 2007 1569
44. W.D. Cao, J.F. Liu, H.B. Qiu, X.R. Yang, and E.K. Wang Simultaneous determination of tramadol and lidocaine in urine by end-column capillary electrophoresis with electrochemiluminescence detection Electroanalysis 14 2002 1571
45. J. Liu, J. Yan, X. Yang, and E. Wang Miniaturized tris(2,2′- bipyridyl)ruthenium(II) electrochemiluminescence detection cell for capillary electrophoresis and flow injection analysis Analytical Chemistry 75 2003 3637