Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 3, 2013, Pages 520-528

  Boukalova, Stepana ^a   Teisinger, Jan ^a   Vlachova, Viktorie ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Gating; Mutagenesis; Transient receptor potential; Tryptophan scanning; Vanilloid receptor subtype 1

Indexed keywords

CAPSAICIN; MUTANT PROTEIN; PROTON; TRYPTOPHAN; VANILLOID RECEPTOR 1;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; GAIN OF FUNCTION MUTATION; HEAT; HUMAN; HUMAN CELL; ION CURRENT; MUTAGENESIS; PH; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; WILD TYPE;

CELLS, CULTURED; HOT TEMPERATURE; HUMANS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; KIDNEY; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, SECONDARY; PROTONS; TRPV CATION CHANNELS;

EID: 84871895296     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.11.017     Document Type: Article

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