Treatment of high-risk venous thrombosis patients using low-dose intraclot injections of recombinant tissue plasminogen activator and regional anticoagulation

Journal of Vascular and Interventional Radiology

Volumn 24, Issue 1, 2013, Pages

  Chang, Richard ^a   Butman, John A ^a   Lonser, Russell R ^b   Sherry, Richard M ^c   Pandalai, Prakash K ^c   Horne III, McDonald K ^a   Lozier, Jay N ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

activated partial thromboplastin time; aPTT; cerebrospinal fluid; CSF; deep vein thrombosis; DVT; tissue plasminogen activator; tPA

Indexed keywords

HEPARIN; TISSUE PLASMINOGEN ACTIVATOR; WARFARIN;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; BLADDER IRRIGATION; CAT SCRATCH DISEASE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; FEMALE; HEMATURIA; HEMORRHOIDECTOMY; HUMAN; HYPOVOLEMIA; KIDNEY CANCER; LOW DRUG DOSE; LUNG EMBOLISM; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PHLEBOGRAPHY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SUBDURAL HEMATOMA; TREATMENT DURATION; URINE INCONTINENCE; VEIN THROMBOSIS; VON HIPPEL LINDAU DISEASE;

EID: 84871872230     PISSN: 10510443     EISSN: 15357732     Source Type: Journal    
DOI: 10.1016/j.jvir.2012.09.017     Document Type: Article

References (14)

1. S. Vedantham, P.E. Thorpe, and J.F. Cardella Quality improvement guidelines for the treatment of lower extremity deep vein thrombosis with use of endovascular thrombus removal J Vasc Interv Radiol 17 2006 435 448
2. H.L. Morrison III Catheter-directed thrombolysis for acute limb ischemia Semin Intervent Radiol 2006 258 269
3. T.T. Horlocker, D.J. Wedel, and J.C. Rowlingson Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy - American Society of Regional Anesthesia and Pain Medicine evidence-based guidelines (3rd edition) Reg Anesth Pain Med 35 2010 64 101
4. R. Chang, M.K. Horne III, and T.H. Shawker Low-dose, once-daily, intraclot injections of alteplase for treatment of acute deep venous thrombosis J Vasc Interv Radiol 22 2011 1107 1116
5. J.N. Lozier, A.M. Cullinane, K. Nghiem, M.K. Horne III, and R. Chang Biochemical dynamics relevant to the safety of low dose, intraclot alteplase for deep vein thrombosis Transl Res 160 2012 217 222
6. R. Chang, R.O. Cannon III, and C.C. Chen Daily catheter-directed single dosing of t-PA in treatment of acute deep venous thrombosis of the lower extremity J Vasc Interv Radiol 12 2001 247 252
7. J. Hirsh Heparin N Engl J Med 324 1991 1565 1574
8. M.N. Levine, J. Hirsh, and M. Gent A randomized trial comparing activated thromboplastin time with heparin assay in patients with acute venous thromboembolism requiring large doses of heparin Arch Intern Med 154 1994 49 56
9. J. Hirsh, R. Raschke, Warkentin, D. Deykin, and L. Poller Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety Chest 108 suppl 1995 258S 275S
10. M.R. Grunwald, and L.V. Hoffman Comparison of urokinase, alteplase, and reteplase for catheter directed thrombolysis of deep vein thrombosis J Vasc Interv Radiol 15 2004 347 352
11. K. Ouriel, B. Gray, D.G. Clair, and J. Olin Complications associated with the use of urokinase and recombinant tissue plasminogen activator for catheter-directed peripheral arterial and venous thrombolysis J Vasc Interv Radiol 11 2000 295 298
12. M.N. Levine, S.Z. Goldhaber, J.M. Gore, J. Hirsh, and R.M. Califf Hemorrhagic complications of thrombolytic therapy in the treatment of myocardial infarction and venous thromboembolism Chest 108 suppl 1995 291S 301S
13. G. Agnelli, M.R. Buchanan, F. Fernandez, J. Van Ryn, and J. Hirsh Sustained thrombolysis with DNA recombinant type tissue plasminogen activator in rabbits Blood 66 1985 399 401
14. G. Agnelli Rationale for bolus t-PA therapy to improve efficacy and safety Chest 97 suppl 1990 161S 167S