Profiling and sequencing of gangliosides from human caudate nucleus by chip-nanoelectrospray mass spectrometry

Journal of Mass Spectrometry

Volumn 47, Issue 12, 2012, Pages 1561-1570

  Serb, Alina F ^a   Sisu, Eugen ^a   Vukelić, Željka ^b   Zamfir, Alina D ^c,d  

^a VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c AUREL VLAICU UNIVERSITY OF ARAD   (Romania)

^d WEST UNIVERSITY OF TIMISOARA   (Romania)

Author keywords

caudate nucleus; chip nanoelectrospray; gangliosides; human brain; tandem mass spectrometry

Indexed keywords

CAUDATE NUCLEUS; CHIP-NANOELECTROSPRAY; GANGLIOSIDES; HUMAN BRAIN; TANDEM MASS SPECTROMETRY;

AMIDES; CARBOXYLIC ACIDS; MASS SPECTROMETRY; SIGNAL PROCESSING;

BRAIN;

CARBON; CERAMIDE; GANGLIOSIDE; LONG CHAIN FATTY ACID;

ARTICLE; ATOM; BRAIN REGION; CAUDATE NUCLEUS; CHIP NANOELECTROSPRAY MASS SPECTROMETRY; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; ION TRAP MASS SPECTROMETRY; LACTONIZATION; MASS SPECTROMETER; NANOMATE ROBOT; PRIORITY JOURNAL; PROTEIN STRUCTURE; ROBOTICS; SIALYLATION; SIGNAL PROCESSING; TANDEM MASS SPECTROMETRY;

ADULT; CARBOHYDRATE SEQUENCE; CAUDATE NUCLEUS; GANGLIOSIDES; HUMANS; LAB-ON-A-CHIP DEVICES; MALE; NANOTECHNOLOGY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84871837141     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.3116     Document Type: Article

References (55)

1. H. Wiegandt,. The chemical constitution of the gangliosides of the vertebrate nervous system. Behav. Brain Res. 1995, 66, 85.
2. S. Ando,. Gangliosides in the nervous system. Neurochem. Int. 1983, 5, 507.
3. R. W. Ledeen,. Gangliosides of the neuron. Trends Neurosci. 1985, 4, 169.
4. S. Hakomori, K. Handa,. Interaction of glycosphingolipids with signal transducers and membrane proteins in glycosphingolipid-enriched microdomains. Methods Enzymol. 2003, 363, 191.
5. L. Mo, Q. Ren, A. M. Duchemin, N. H. Neff, M. Hadjiconstantinou,. GM1 and ERK signaling in the aged brain. Brain Res. 2005, 1054, 125.
6. A. R. Todeschini, S. Hakomori,. Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. Biochim. Biophys. Acta 2008, 1780, 421.
7. H. Rösner,. Developmental expression and possible roles of gangliosides in brain development. Prog. Mol. Subcell. Biol. 2003, 32, 49.
8. E. Posse de Chaves, S. Sipione,. Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction. FEBS Lett. 2010, 584, 1748.
9. J. Abad-Rodriguez, A. Robotti,. Regulation of axonal development by plasma membrane gangliosides. J. Neurochem. 2007, 103, 47.
10. I. Kračun, H. Rösner, V. Drnovšek, ć. Vukelić, C. Cosović, M. Trbojević-Čepe, M. Kubat,. Gangliosides in the human brain development and aging. Neurochem. Int. 1992, 20, 421.
11. S. Hakomori,. The glycosynapse. Proc. Natl. Acad. Sci. 2002, 99, 225.
12. M. Ono, S. Hakomori,. Glycosylation defining cancer cell motility and invasiveness. Glycoconj. J. 2004, 20, 71.
13. I. Mocchetti,. Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins. Cell. Mol. Life Sci. 2005, 62, 2283.
14. D. H. Kwak, S. M. Kim, D. H. Lee, J. S. Kim, S. M. Kim, S. U. Lee, K. Y. Jung, B. B. Seo, Y. K. Choo,. Differential expression patterns of gangliosides in the ischemic cerebral cortex produced by middle cerebral artery occlusion. Mol. Cells 2005, 20, 354.
15. S. Sonnino, V. Chigorno,. Ganglioside molecular species containing C18- and C20-sphingosine in mammalian nervous tissues and neuronal cell cultures. Biochim. Biophys. Acta 2000, 1469, 63.
16. L. Svennerholm, B. M. Rynmark, G. Vilbergsson, P. Fredman, J. Gottfries, J. E. Mansson, A. Percy,. Gangliosides in human fetal brain. J. Neurochem. 1991, 56, 1763.
17. L. Svennerholm, K. Bostrom, B. Jungbjer, L. Olsson,. Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years. J. Neurochem. 1994, 63, 1802.
18. M. Stojiljković, T. Blagojević, S. Vukosavić, N. D. Zvezdina, S. Peković, G. Nikezić, L. Rakić,. Ganglioside GM1 and GM3 in early human brain development: an immunocytochemical study. Int. J. Dev. Neurosci. 1996, 14, 35.
19. S. Marconi, L. De Toni, L. Lovato, E. Tedeschi, L. Gaetti, M. Acler, B. Bonetti,. Expression of gangliosides on glial and neuronal cells in normal and pathological adult human brain. J. Neuroimmunol. 2005, 170, 115.
20. T. C. Comas, T. Tai, D. Kimmel, B. W. Scheithauer, P. C. Burger, D. K. Pearl, S. D. Jewell, A. J. Yates,. Immunohistochemical staining for ganglioside GD1b as a diagnostic and prognostic marker for primary human brain tumors. Neuro Oncol. 1999, 1, 261.
21. J. Muthing, U. Distler,. Advances on the compositional analysis of glycosphingolipids combining thin-layer chromatography with mass spectrometry. Mass Spectrom. Rev. 2010, 29, 425.
22. ć. Vukelić, W. Metelmann, J. Müthing, M. Kos, J. Peter-Katalinić,. Anencephaly: structural characterization of gangliosides in defined brain regions. Biol. Chem. 2001, 382, 259.
23. R. Wagener, B. Kobbe, W. Stoffel, Quantification of gangliosides by microbore high performance liquid chromatography. J. Lipid Res. 1996, 37, 1823.
24. J. Müthing,. High-resolution thin-layer chromatography of gangliosides. J. Chromatogr. A 1996, 720, 3.
25. M. Iwamori, Y. Nagai,. Isolation and characterization of a novel ganglioside, monosialosyl pentahexaosyl ceramide from human brain. J. Biochem. 1978, 84, 1601.
26. A. D. Zamfir, L. Bindila, N. Lion, M. Allen, H. H. Girault, J. Peter-Katalinić,. Chip electrospray mass spectrometry for carbohydrate analysis. Electrophoresis 2005, 26, 3650.
27. A. D. Zamfir, ć. Vukelić, A. Schneider, E. Sisu, N. Dinca, A. Ingendoh,. A novel approach for ganglioside structural analysis based on electrospray multiple-stage mass spectrometry. J. Biomol. Tech. 2007, 18, 188.
28. ć. Vukelić, M. Zarei, J. Peter-Katalinić, A. D. Zamfir,. Analysis of human hippocampus gangliosides by fully-automated chip-based nanoelectrospray tandem mass spectrometry. J. Chromatogr. A 2006, 1130, 238.
29. C. Mosoarca, R. M. Ghiulai, C. R. Novaconi, ć. Vukelić, A. Chiriac, A. D. Zamfir,. Application of chip-based nanoelectrospray ion trap mass spectrometry to compositional and structural analysis of gangliosides in human fetal cerebellum, Anal. Lett. 2011, 44, 1036.
30. A. Zamfir, ć. Vukelić, L. Bindila, R. Almeida, A. Sterling, M. Allen, J. Peter-Katalinic,. Fully automated chip-based nanoelectrospray tandem mass spectrometry of gangliosides from human cerebellum. J. Am. Soc. Mass Spectrom. 2004, 15, 1649.
31. R. Almeida, C. Mosoarca, M. Chirita, V. Udrescu, N. Dinca, ć. Vukelić, M. Allen, A. D. Zamfir,. Coupling of fully automated chip-based electrospray ionization to high- capacity ion trap mass spectrometer for ganglioside analysis. Anal. Biochem. 2008, 378, 43.
32. A. Serb, C. Schiopu, C. Flangea, ć. Vukelić, E. Sisu, L. Zagrean, A. D. Zamfir,. High throughput analysis of gangliosides in defined regions of fetal brain by fully automated chip-based nanoelectrospray ionization multi-stage mass spectrometry. Eur. J. Mass Spectrom. 2009, 5, 541.
33. ć. Vukelić, S. Kalanj-Bognar, M. Froesch, L. Bindila, B. Radic, M. Allen, J. Peter-Katalinic, A. D. Zamfir,. Human gliosarcoma-associated ganglioside composition is complex and distinctive as evidenced by high-performance mass spectrometric determination and structural characterization. Glycobiology 2007, 17, 504.
34. C. Schiopu, C. Flangea, F. Capitan, A. Serb, ć. Vukelić, S. Kalanj-Bognar, E. Sisu, M. Przybylski, A. D. Zamfir,. Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionisation tandem mass spectrometry. Anal. Bioanal. Chem. 2009, 395, 2465.
35. C. Schiopu, ć. Vukelić, F. Capitan, E. Sisu, A. D. Zamfir,. Chip-nanoelectrospray quadrupole time-of-flight tandem mass spectrometry of meningioma gangliosides: A preliminary study. Electrophoresis 2012, 33, 1778.
36. A. D. Zamfir, A. Serb, ć. Vukelić, C. Flangea, C. Schiopu, D. Fabris, S. Kalanj-Bognar, F. Capitan, E. Sisu,. Assessment of the Molecular Expression and Structure of Gangliosides in Brain Metastasis of Lung Adenocarcinoma by an Advanced Approach Based on Fully Automated Chip-Nanoelectrospray Mass Spectrometry. J. Am. Soc. Mass Spectrom. 2011, 22, 2145.
37. J. Rothwell,. Control of Human Voluntary Movement, 2nd ed,. Chapman & Hall: London, 1994.
38. F. O. Walker,. Huntington's disease. Lancet 2007, 369, 218.
39. M. A. Butters, H. J. Aizenstein, K. M. Hayashi, C. C. Meltzer, J. Seaman, C. F. Reynolds, A. W. Toga, P. M. Thompson, J. T. Becker,. Three-dimensional surface mapping of the caudate nucleus in late-life depression. Am. J. Geriatr. Psychiatry 2009, 17, 4.
40. D. D. Dougherty, A. A. Bonab, T. J. Spencer, S. L. Rauch, B. K. Madras, A. J. Fischman,. Dopamine transporter density in patients with attention deficit hyperactivity disorder. Lancet 1999, 354, 2132.
41. K. Takase, C. Tamagaki, G. Okugawa, K. Nobuhara, T. Minami, T. Sugimoto, S. Sawada, T. Kinoshita,. Reduced White Matter Volume of the Caudate Nucleus in Patients with Schizophrenia. Neuropsychobiology 2004, 50, 296.
42. E. S. Hansen, S. Hasselbalch, I. Law, T. G. Bolwig,. The caudate nucleus in obsessive-compulsive disorder. Reduced metabolism following treatment with paroxetine: a PET study. Int. J. Neuropsychopharm. 2002, 5, 1.
43. J. Bogousslavsky, J. L. Cummings,. Behavior and Mood Disorders in Focal Brain Lesions. Cambridge University Press: Cambridge, UK, 2000.
44. H. Bernheimer, G. Sperk, K. S. Price, O. Hornykiewicz,. Brain gangliosides in Huntington's disease. Adv. Neurol. 1979, 23, 463.
45. P. A. Desplats, C. A. Denny, K. E. Kass, T. Gilmartin, S. R. Head, J. G. Sutcliffe, T. N. Seyfried, E. A. Thomasa,. Glycolipid and ganglioside metabolism imbalances in Huntington's disease. Neurobiol. Dis. 2007, 27, 265.
46. M. R. Higatsberger, G. Sperk, H. Bernheimer, K. S. Shannak, O. Hornykiewicz,. Striatal ganglioside levels in the rat following kainic acid lesions: comparison with HuntingtonTs disease. Exp. Brain Res. 1981, 44, 93.
47. L. Svennerholm, P. Fredman,. A procedure for the quantitative isolation of brain gangliosides. Biochim. Biophys. Acta 1980, 617, 97.
48. IUPAC-IUB Joint Commission on Biochemical Nomenclature. Nomenclature of glycolipids. Recommendations 1997. Eur. J. Biochem. 1998, 257, 293.
49. B. Domon, C. E. Costello,. A systematic nomenclature for carbohydrate fragmentation in FAB-MS/MS spectra of glycoconjugates. Glycoconj. J. 1988, 5, 397.
50. C. E. Costello, P. Juhasz, H. Perreault,. New mass spectral approaches to ganglioside structure determination. Progr. Brain Res. 1994, 101, 45.
51. + ions. J. Am. Soc. Mass Spectrom. 1992, 3, 260.
52. A. D. Zamfir, C. Flangea, F. Altmann, A. Rizzi,. Glycosylation analysis of proteins, proteoglycans, and glycolipids using capillary electrophoresis and mass spectrometry. Adv. Chromatogr. 2011, 49, 135.
53. A. Serb, C. Schiopu, C. Flangea, E. Sisu, A.D. Zamfir,. Top-down glycolipidomics: fragmentation analysis of ganglioside oligosaccharide core and ceramide moiety by chip-nanoelectrospray collision-induced dissociation MS(2)-MS(6). J. Mass Spectrom. 2009, 44, 1434.
54. W. Metelmann, ć. Vukelić, J. Peter-Katalinić,. Nano-electrospray ionization time-of-flight mass spectrometry of gangliosides from human brain tissue. J. Mass Spectrom. 2001, 36, 21.
55. ć. Vukelić, A. D. Zamfir, L. Bindila, M. Froesch, J. Peter-Katalinić, S. Usuki, R. K. Yu,. Screening and sequencing of complex sialylated and sulfated glycosphingolipid mixtures by negative ion electro-spray Fourier transform ion cyclotron resonance mass spectrometry. J. Am. Soc. Mass Spectrom. 2005, 16, 571.