Gecko crude peptides induce apoptosis in human liver carcinoma cells in vitro and exert antitumor activity in a mouse ascites H22 xenograft model

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Song, Ying ^a   Wang, Jian Gang ^a   Li, Rui Fang ^a   Li, Yan ^a   Cui, Zhao Chu ^a   Duan, Leng Xin ^a   Lu, Fei ^a  

^a HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; FLUOROURACIL; GECKO CRUDE PEPTIDE; INTERLEUKIN 6; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASCITES; CANCER INHIBITION; CARCINOMA CELL; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; GEKKO JAPONICUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE COUNT; LIVER CELL CARCINOMA; MEDICINAL PLANT; MORPHOLOGY; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; DRUG EFFECT; LIVER TUMOR; LIZARD; METABOLISM; PATHOLOGY; TREATMENT OUTCOME; TUMOR CELL LINE;

GEKKONIDAE; MUS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; LIZARDS; MICE; PEPTIDES; TREATMENT OUTCOME;

EID: 84871824170     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/743573     Document Type: Article

References (24)

1. Yeung B. H. Y., Wong K. Y., Lin M. C., Wong C. K. C., Mashima T., Tsuruo T., Wong A. S. T., Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2. British Journal of Cancer 2008 99 2 283 293 2-s2.0-48249146576 10.1038/sj.bjc.6604477
2. Tanaka T., Toujima S., Utsunomiya T., Yukawa K., Umesaki N., Experimental characterization of recurrent ovarian immature teratoma cells after optimal surgery. Oncology Reports 2008 20 1 13 23 2-s2.0-49849084483
3. Zhang J. L., Wen H. M., Sun D. J., Purification and antitumor effects of a small peptide from snake venom of Gloydius saxatilis. Chinese Journal of Biochemical Pharmaceutics 2009 30 4 217 220
4. Zhang W. D., Zhang Y. Y., Wang C. X., Effect of polypeptide extract from scorpion venom on tumor growth and cellular immunity in rats with W256 sarcocarcinoma. Journal of Shandong Univercity 2007 45 3 286 289
5. Zhao F., Liu P. X., Progress of study on action mechanisms of TCM in anti-tumor and preventing metastasis of tumor. Zhongguo Zhongxiyi Jiehe Zazhi 2007 27 2 178 181 2-s2.0-42449092111
6. He Y. H., General survey of traditional Chinese medicine and Western medicine researches on tumor metastasis. Chinese Journal of Integrative Medicine 2006 12 1 75 80 2-s2.0-33645537656 10.1007/BF02857438
7. Zhang S. F., Chen Z., Li B., Progress on research and application of traditional Chinese medicine in intervention treatment of primary liver carcinoma. Zhongguo Zhongxiyi Jiehe Zazhi 2006 26 8 759 763 2-s2.0-38049050427
8. Yang J. X., Wang X. M., Progress in studies on anti-hepatoma effect of traditional Chinese medicine by adjusting immune function. Zhongguo Zhongyao Zazhi 2007 32 4 281 284 2-s2.0-34247282784
9. Liu F., Wang J. G., Wang S. Y., Li Y., Wu Y. P., Xi S. M., Antitumor effect and mechanism of Gecko on human esophageal carcinoma cell lines in vitro and xenografted sarcoma 180 in Kunming mice. World Journal of Gastroenterology 2008 14 25 3990 3996 2-s2.0-53449088138 10.3748/wjg.14.3990
10. Xiaolan W., Hengyou H., Study on the antitumor effects and synergism and attenuation effects of Gecko Alcohol Extract. Journal of Chinese Medicinal Materials 2010 33 8 1213 1216
11. Yang J. X., Wang X. M., Progress study and research on treating tumor of Gecko. Chinese Journal of Digestion 2006 14 2428 2431
12. Wu B. D., Treatment of 105 cases of esophagus tumor by compound recipe of Gecko. Zhongguo Zhongxiyi Jiehe Za Zhi 1999 19 502
13. Song P., Wang X. M., Xie S., Experimental study on mechanisms of lyophilized powder of fresh gekko Chinenis in inhibiting H22 hepatocarcinoma angiogenesis. Zhongguo Zhongxiyi Jiehe Zazhi 2006 26 1 58 62 2-s2.0-38049095128
14. Fu J., Huang H., Liu J., Pi R., Chen J., Liu P., Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis. European Journal of Pharmacology 2007 568 1-3 213 221 2-s2.0-34250814485 10.1016/j.ejphar.2007.04.031 (Pubitemid 46976900)
15. Wang L., Mao J., Zhang G. H., Tu M. J., Nano-cerium-element-doped titanium dioxide induces apoptosis of Bel 7402 human hepatoma cells in the presence of visible light. World Journal of Gastroenterology 2007 13 29 4011 4014 2-s2.0-34547969744 (Pubitemid 47272502)
16. Yuan S. L., Wei Y. Q., Wang X. J., Xiao F., Li S. F., Zhang J., Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells. World Journal of Gastroenterology 2004 10 14 2024 2028 2-s2.0-4043125279 (Pubitemid 39106951)
17. Zhen X., Cen J., Li Y. M., Yan F., Guan T., Tang X. Z., Cytotoxic effect and apoptotic mechanism of tanshinone A, a novel tanshinone derivative, on human erythroleukemic K562 cells. European Journal of Pharmacology 2011 667 129 135 2-s2.0-79960011474 10.1016/j.ejphar.2011.06.004
18. Kakita T., Hasegawa K., Morimoto T., Kaburagi S., Wada H., Sasayama S., p300 Protein as a coactivator of GATA-5 in the transcription of cardiac- restricted atrial natriuretic factor gene. Journal of Biological Chemistry 1999 274 48 34096 34102 2-s2.0-0033607539 10.1074/jbc.274.48.34096 (Pubitemid 129511744)
19. Chen W. J., Huang Y. T., Wu M. L., Huang T. C., Ho C. T., Pan M. H., Induction of apoptosis by vitamin D2, ergocalciferol, via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. Journal of Agricultural and Food Chemistry 2008 56 9 2996 3005 2-s2.0-44349130527 10.1021/jf0730744 (Pubitemid 351746020)
20. Li J., Xia X., Nie H., Smith M. A., Zhu X., PKC inhibition is involved in trichosanthin-induced apoptosis in human chronic myeloid leukemia cell line K562. Biochimica et Biophysica Acta 2007 1770 1 63 70 2-s2.0-33845528947 10.1016/j.bbagen.2006.07.011 (Pubitemid 44920351)
21. Park S. Y., Yang H. C., Moon J. Y., Lee N. H., Kim S. J., Kang J. H., Lee Y. K., Park D. B., Yoo E. S., Kang H. K., Induction of the apoptosis of HL-60 promyelocytic leukemia cells by Eurya emarginata. Cancer Letters 2004 205 1 31 38 2-s2.0-1242293657 10.1016/j.canlet.2003.09.034 (Pubitemid 38230136)
22. Zhang G. S., Tu C. Q., Zhang G. Y., Zhou G. B., Zheng W. L., Indomethacin induces apoptosis and inhibits proliferation in chronic myeloid leukemia cells. Leukemia Research 2000 24 5 385 392 2-s2.0-0343293999 10.1016/S0145-2126(99) 00198-8 (Pubitemid 30227238)
23. Zhen X., Li Y. M., Fang W. R., Yan F., Cen J., Mao L. S., Study on the effects of tanshinone derivates on growth inhibition and apoptosis induction in human erythroleukemia cell line K562. Chinese Pharmacological Bulletin 2008 24 7 964 968 2-s2.0-56049112608
24. Cory S., Adams J. M., The BCL2 family: regulators of the cellular life-or-death switch. Nature Reviews Cancer 2002 2 9 647 656 2-s2.0-0036716281 10.1038/nrc883 (Pubitemid 37328916)