Painting blood vessels and atherosclerotic plaques with an adhesive drug depot

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 52, 2012, Pages 21444-21449

  Kastrup, Christian J ^a,c   Nahrendorf, Matthias ^d   Figueiredo, JoseLuiz ^d   Lee, Haeshin ^e   Kambhampati, Swetha ^a   Lee, Timothy ^a   Cho, Seung Woo ^f   Gorbatov, Rostic ^d   Iwamoto, Yoshiko ^d   Dang, Tram T ^a   Dutta, Partha ^d   Yeon, Ju Hun ^c   Cheng, Hao ^a,g   Pritchard, Christopher D ^a   Vegas, Arturo J ^a   Siegel, Cory D ^d   MacDougall, Samantha ^a   Okonkwo, Michael ^a   Thai, Anh ^a   Stone, James R ^d   Coury, Arthur J ^h   Weissleder, Ralph ^d   Langer, Robert ^a,b   Anderson, Daniel G ^a,b   more..

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^f Yonsei University   (South Korea)

^g Drexel University   (United States)

^h NONE   (United States)

Author keywords

Biomaterials; Catechol; Delivery; Endoluminal paving

Indexed keywords

CATECHOL; CD11B ANTIGEN; CD31 ANTIGEN; CYTOKINE; DEXAMETHASONE SODIUM PHOSPHATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ADHESION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; DRUG ELUTING BIOADHESIVE GEL; FEMALE; FIBROSIS; GEL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SHEAR STRESS; SMOOTH MUSCLE FIBER; STEROID THERAPY;

ADHESIVENESS; ADHESIVES; ANIMALS; APOLIPOPROTEINS E; ARTERIES; BLOOD VESSELS; CATECHOLS; DEXAMETHASONE; DRUG DELIVERY SYSTEMS; FEMALE; GELS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IMPLANTS, EXPERIMENTAL; INFLAMMATION; MICE; MICE, INBRED C57BL; PLAQUE, ATHEROSCLEROTIC; SOLUBILITY; STRESS, MECHANICAL; STRESS, PHYSIOLOGICAL;

MYTILIDAE;

EID: 84871822549     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217972110     Document Type: Article

References (34)

1. Simone E, Ding BS, Muzykantov V (2009) Targeted delivery of therapeutics to endothelium. Cell Tissue Res 335(1):283-300.
2. Hansson GK (2005) Infl ammation, atherosclerosis, and coronary artery disease. N Engl J Med 352(16):1685-1695.
3. Fayad ZA, et al.; dal-PLAQUE Investigators (2011) Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal- PLAQUE): A randomised clinical trial. Lancet 378(9802):1547-1559.
4. Jaffer FA, Libby P, Weissleder R (2007) Molecular imaging of cardiovascular disease. Circulation 116(9):1052-1061. (Pubitemid 47329570)
5. Leuschner F, Nahrendorf M (2011) Molecular imaging of coronary atherosclerosis and myocardial infarction: Considerations for the bench and perspectives for the clinic. Circ Res 108(5):593-606.
6. Sanz J, Fayad ZA (2008) Imaging of atherosclerotic cardiovascular disease. Nature 451(7181):953-957. (Pubitemid 351305938)
7. Spratt JC, Camenzind E (2004) Plaque stabilisation by systemic and local drug administration. Heart 90(12):1392-1394. (Pubitemid 39626307)
8. Lobatto ME, Fuster V, Fayad ZA, Mulder WJM (2011) Perspectives and opportunities for nanomedicine in the management of atherosclerosis. Nat Rev Drug Discov 10(11):835-852.
9. LaVan DA, McGuire T, Langer R (2003) Small-scale systems for in vivo drug delivery. Nat Biotechnol 21(10):1184- 1191.
10. Chan JM, et al. (2010) Spatiotemporal controlled delivery of nanoparticles to injured vasculature. Proc Natl Acad Sci USA 107(5):2213-2218.
11. Slepian MJ, Hubbell JA (1997) Polymeric endoluminal gel paving: Hydrogel systems for local barrier creation and site-specific drug delivery. Adv Drug Deliv Rev 24(1):11-30. (Pubitemid 27062758)
12. Waxman S, Ishibashi F, Muller JE (2006) Detection and treatment of vulnerable plaques and vulnerable patients: Novel approaches to prevention of coronary events. Circulation 114(22):2390-2411. (Pubitemid 44848285)
13. Parikh SA, Costa MA (2009) Secondary prevention, the interventional way: Prophylactic drug-eluting stents for nonobstructive saphenous vein graft disease. Circulation 120(20):1940-1942.
14. Farb A, Burke AP, Kolodgie FD, Virmani R (2003) Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation 108(14):1701-1706. (Pubitemid 37243657)
15. Kuchulakanti PK, et al. (2006) Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents. Circulation 113(8):1108- 1113.
16. Ramcharitar S, et al. (2009) First case of stenting of a vulnerable plaque in the SECRITT I trial-the dawn of a new era? Nat Rev Cardiol 6(5):374-378.
17. Hill-West JL, Chowdhury SM, Slepian MJ, Hubbell JA (1994) Inhibition of thrombosis and intimal thickening by in situ photopolymerization of thin hydrogel barriers. Proc Natl Acad Sci USA 91(13):5967-5971. (Pubitemid 24188263)
18. Thierry B, Winnik FM, Merhi Y, Tabrizian M (2003) Nanocoatings onto arteries via layer-by-layer deposition: Toward the in vivo repair of damaged blood vessels. J Am Chem Soc 125(25):7494-7495. (Pubitemid 36750252)
19. Livnat M, Beyar R, Seliktar D (2005) Endoluminal hydrogel films made of alginate and polyethylene glycol: Physical characteristics and drug-eluting properties. J Biomed Mater Res A 75(3):710-722. (Pubitemid 47233455)
20. West JL, Hubbell JA (1996) Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: The roles of medial and luminal factors in arterial healing. Proc Natl Acad Sci USA 93(23):13188-13193. (Pubitemid 26382791)
21. Coyne KJ, Qin XX, Waite JH (1997) Extensible collagen in mussel byssus: A natural block copolymer. Science 277(5333):1830-1832. (Pubitemid 27449196)
22. Harrington MJ, Masic A, Holten-Andersen N, Waite JH, Fratzl P (2010) Iron-clad fibers: a metal-based biological strategy for hard flexible coatings. Science 328(5975):216-220.
23. Lee BP, Dalsin JL, Messersmith PB (2002) Synthesis and gelation of DOPA-modified poly(ethylene glycol) hydrogels. Biomacromolecules 3(5):1038-1047.
24. Ryu JH, et al. (2011) Catechol-functionalized chitosan/pluronic hydrogels for tissue adhesives and hemostatic materials. Biomacromolecules 12(7):2653-2659.
25. Brubaker CE, Kissler H, Wang L-J, Kaufman DB, Messersmith PB (2010) Biological performance of mussel-inspired adhesive in extrahepatic islet transplantation. Biomaterials 31(3):420-427.
26. Lee H, et al. (2008) Substrate-independent layer-by-layer assembly by using mussel-adhesive- inspired polymers. Adv Mater 20(9):1619-1623.
27. Libby P (2008) The molecular mechanisms of the thrombotic complications of atherosclerosis. J Intern Med 263(5):517-527.
28. Augst AD, Kong HJ, Mooney DJ (2006) Alginate hydrogels as biomaterials. Macromol Biosci 6(8):623-633. (Pubitemid 44329266)
29. Gnasso A, et al. (1996) Association between intima-media thickness and wall shear stress in common carotid arteries in healthy male subjects. Circulation 94(12):3257-3262. (Pubitemid 26427496)
30. Bajpai SK, Sharma S (2004) Investigation of swelling/degradation behaviour of alginate beads crosslinked with Ca2+ and Ba2+ ions. React Funct Polym 59(2):129-140.
31. Hunt NC, Smith AM, Gbureck U, Shelton RM, Grover LM (2010) Encapsulation of fibroblasts causes accelerated alginate hydrogel degradation. Acta Biomater 6(9):3649-3656.
32. Aikawa E, et al. (2007) Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease. Circulation 115(3):377-386. (Pubitemid 46148512)
33. Granada JF, et al. (2009) Porcine models of coronary atherosclerosis and vulnerable plaque for imaging and interventional research. EuroIntervention 5(1):140-148.
34. Bouhadir KH, et al. (2001) Degradation of partially oxidized alginate and its potential application for tissue engineering. Biotechnol Prog 17(5):945-950. (Pubitemid 32972660)