Is the serum amyloid A we use really serum amyloid A? Comment on the article by Connolly et al

Arthritis and Rheumatism

Volumn 65, Issue 1, 2013, Pages 283-284

  Van Den Brand, Ben ^a   Waterborg, Claire ^a   Van Den Berg, Wim ^a   Van De Loo, Fons ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; HISTIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 23P19; INTERLEUKIN 8; MESSENGER RNA; SERUM AMYLOID A;

AMINO ACID SUBSTITUTION; CELL STIMULATION; FIBROBLAST; HUMAN; ISOELECTRIC POINT; LETTER; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; RHEUMATOID ARTHRITIS;

ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISEASE PROGRESSION; FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MALE; SERUM AMYLOID A PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84871807977     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37737     Document Type: Letter

References (6)

1. Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, et al. Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy. Arthritis Rheum 2012; 64: 1035-45.
2. Migita K, Koga T, Torigoshi T, Motokawa S, Maeda Y, Jiuchi Y, et al. Induction of interleukin-23 p19 by serum amyloid A (SAA) in rheumatoid synoviocytes. Clin Exp Immunol 2010; 162: 244-50.
3. Niemi K, Teirila L, Lappalainen J, Rajamaki K, Baumann MH, Oorni K, et al. Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway. J Immunol 2011; 186: 6119-28.
4. Connolly M, Marrelli A, Blades M, McCormick J, Maderna P, Godson C, et al. Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model. J Immunol 2010; 184: 6427-37.
5. Connolly M, Veale DJ, Fearon U,. Acute serum amyloid A regulates cytoskeletal rearrangement, cell matrix interactions and promotes cell migration in rheumatoid arthritis. Ann Rheum Dis 2011; 70: 1296-303.
6. Bjorkman L, Raynes JG, Shah C, Karlsson A, Dahlgren C, Bylund J,. The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation. Arthritis Rheum 2010; 62: 1660-5.