Nucleophilic 5-endo-trig cyclization of 3,3-difluoroallylic ketone enolates: Synthesis of 5-fluorinated 2-alkylidene-2,3-dihydrofurans

Synlett

Volumn 24, Issue 1, 2013, Pages 57-60

  Fujita, Takeshi ^a   Sakoda, Kotaro ^b   Ikeda, Masahiro ^a   Hattori, Masahiro ^a   Ichikawa, Junji ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

5 endo trig; alkenes; cyclization; fluorine; furans; ketone enolates; vinylic substitution

Indexed keywords

2 ALKYLIDENE 2,3 DIHYDROFURAN DERIVATIVE; 3,3 DIFLUOROALLYLIC KETONE ENOLATE DERIVATIVE; FLUORINE DERIVATIVE; FURAN DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLIZATION; FLUORINATION; NUCLEOPHILICITY; REACTION ANALYSIS; SYNTHESIS;

EID: 84871718941     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0032-1317709     Document Type: Article

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