-
1
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher PM, Brown MA, McCarthy MI, Yang J, (2012) Five years of GWAS discovery. Am J Hum Genet 90: 7-24.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
2
-
-
78549251736
-
Analysing biological pathways in genome-wide association studies
-
Wang K, Li M, Hakonarson H, (2010) Analysing biological pathways in genome-wide association studies. Nat Rev Genet 11: 843-854.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 843-854
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
3
-
-
34547146985
-
Network medicine-from obesity to the "diseasome"
-
Barabasi AL, (2007) Network medicine-from obesity to the "diseasome". N Engl J Med 357: 404-407.
-
(2007)
N Engl J Med
, vol.357
, pp. 404-407
-
-
Barabasi, A.L.1
-
4
-
-
58849112975
-
Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
-
Askland K, Read C, Moore J, (2009) Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission. Hum Genet 125: 63-79.
-
(2009)
Hum Genet
, vol.125
, pp. 63-79
-
-
Askland, K.1
Read, C.2
Moore, J.3
-
5
-
-
34347338776
-
A genomic pathway approach to a complex disease: axon guidance and Parkinson disease
-
Lesnick TG, Papapetropoulos S, Mash DC, Ffrench-Mullen J, Shehadeh L, et al. (2007) A genomic pathway approach to a complex disease: axon guidance and Parkinson disease. PLoS Genet 3: e98.
-
(2007)
PLoS Genet
, vol.3
-
-
Lesnick, T.G.1
Papapetropoulos, S.2
Mash, D.C.3
Ffrench-Mullen, J.4
Shehadeh, L.5
-
6
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
-
7
-
-
36249029788
-
Pathway-based approaches for analysis of genomewide association studies
-
Wang K, Li M, Bucan M, (2007) Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet 81: 1278-1283.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1278-1283
-
-
Wang, K.1
Li, M.2
Bucan, M.3
-
8
-
-
77955981355
-
Genome-wide gene and pathway analysis
-
Luo L, Peng G, Zhu Y, Dong H, Amos CI, et al. (2010) Genome-wide gene and pathway analysis. Eur J Hum Genet 18: 1045-1053.
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 1045-1053
-
-
Luo, L.1
Peng, G.2
Zhu, Y.3
Dong, H.4
Amos, C.I.5
-
9
-
-
77954246243
-
i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study
-
Zhang K, Cui S, Chang S, Zhang L, Wang J, (2010) i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. Nucleic Acids Res 38: W90-95.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Zhang, K.1
Cui, S.2
Chang, S.3
Zhang, L.4
Wang, J.5
-
10
-
-
70349991890
-
The SNP ratio test: pathway analysis of genome-wide association datasets
-
O'Dushlaine C, Kenny E, Heron EA, Segurado R, Gill M, et al. (2009) The SNP ratio test: pathway analysis of genome-wide association datasets. Bioinformatics 25: 2762-2763.
-
(2009)
Bioinformatics
, vol.25
, pp. 2762-2763
-
-
O'Dushlaine, C.1
Kenny, E.2
Heron, E.A.3
Segurado, R.4
Gill, M.5
-
11
-
-
67651053605
-
Pathway analysis by adaptive combination of P-values
-
Yu K, Li Q, Bergen AW, Pfeiffer RM, Rosenberg PS, et al. (2009) Pathway analysis by adaptive combination of P-values. Genet Epidemiol 33: 700-709.
-
(2009)
Genet Epidemiol
, vol.33
, pp. 700-709
-
-
Yu, K.1
Li, Q.2
Bergen, A.W.3
Pfeiffer, R.M.4
Rosenberg, P.S.5
-
12
-
-
58349112341
-
Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways
-
Chen L, Zhang L, Zhao Y, Xu L, Shang Y, et al. (2009) Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways. Bioinformatics 25: 237-242.
-
(2009)
Bioinformatics
, vol.25
, pp. 237-242
-
-
Chen, L.1
Zhang, L.2
Zhao, Y.3
Xu, L.4
Shang, Y.5
-
13
-
-
77954701060
-
Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD
-
Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, et al. (2010) Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. J Bone Miner Res 25: 1572-1580.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1572-1580
-
-
Zhang, L.1
Guo, Y.F.2
Liu, Y.Z.3
Liu, Y.J.4
Xiong, D.H.5
-
14
-
-
84867742795
-
Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets
-
de Las Fuentes L, Yang W, Davila-Roman VG, Charles Gu C, (2012) Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets. Eur J Hum Genet.
-
(2012)
Eur J Hum Genet
-
-
de Las Fuentes, L.1
Yang, W.2
Davila-Roman, V.G.3
Charles Gu, C.4
-
15
-
-
78649912197
-
Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity
-
Liu YJ, Guo YF, Zhang LS, Pei YF, Yu N, et al. (2010) Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity. Obesity (Silver Spring) 18: 2339-2346.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 2339-2346
-
-
Liu, Y.J.1
Guo, Y.F.2
Zhang, L.S.3
Pei, Y.F.4
Yu, N.5
-
16
-
-
78049508078
-
Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components
-
Mei H, Chen W, Dellinger A, He J, Wang M, et al. (2010) Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components. BMC Genet 11: 100.
-
(2010)
BMC Genet
, vol.11
, pp. 100
-
-
Mei, H.1
Chen, W.2
Dellinger, A.3
He, J.4
Wang, M.5
-
17
-
-
77954187595
-
Analyze multivariate phenotypes in genetic association studies by combining univariate association tests
-
Yang Q, Wu H, Guo CY, Fox CS, (2010) Analyze multivariate phenotypes in genetic association studies by combining univariate association tests. Genet Epidemiol 34: 444-454.
-
(2010)
Genet Epidemiol
, vol.34
, pp. 444-454
-
-
Yang, Q.1
Wu, H.2
Guo, C.Y.3
Fox, C.S.4
-
18
-
-
67649584052
-
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
-
Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, et al. (2009) Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet 85: 13-24.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 13-24
-
-
Holmans, P.1
Green, E.K.2
Pahwa, J.S.3
Ferreira, M.A.4
Purcell, S.M.5
-
19
-
-
6344263668
-
Polymorphism in the growth hormone gene, weight in infancy, and adult bone mass
-
Dennison EM, Syddall HE, Rodriguez S, Voropanov A, Day IN, et al. (2004) Polymorphism in the growth hormone gene, weight in infancy, and adult bone mass. J Clin Endocrinol Metab 89: 4898-4903.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4898-4903
-
-
Dennison, E.M.1
Syddall, H.E.2
Rodriguez, S.3
Voropanov, A.4
Day, I.N.5
-
20
-
-
70350231775
-
The role of Akt1 in terminal stages of endochondral bone formation: angiogenesis and ossification
-
Ulici V, Hoenselaar KD, Agoston H, McErlain DD, Umoh J, et al. (2009) The role of Akt1 in terminal stages of endochondral bone formation: angiogenesis and ossification. Bone 45: 1133-1145.
-
(2009)
Bone
, vol.45
, pp. 1133-1145
-
-
Ulici, V.1
Hoenselaar, K.D.2
Agoston, H.3
McErlain, D.D.4
Umoh, J.5
-
21
-
-
67650475925
-
A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study
-
Dennison EM, Syddall HE, Jameson KA, Sayer AA, Gaunt TR, et al. (2009) A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study. J Rheumatol 36: 1520-1526.
-
(2009)
J Rheumatol
, vol.36
, pp. 1520-1526
-
-
Dennison, E.M.1
Syddall, H.E.2
Jameson, K.A.3
Sayer, A.A.4
Gaunt, T.R.5
-
22
-
-
4043096448
-
Insulin-like growth factor I gene microsatellite repeat, collagen type Ialpha1 gene Sp1 polymorphism, and bone disease in primary biliary cirrhosis
-
Lakatos PL, Bajnok E, Tornai I, Folhoffer A, Horvath A, et al. (2004) Insulin-like growth factor I gene microsatellite repeat, collagen type Ialpha1 gene Sp1 polymorphism, and bone disease in primary biliary cirrhosis. Eur J Gastroenterol Hepatol 16: 753-759.
-
(2004)
Eur J Gastroenterol Hepatol
, vol.16
, pp. 753-759
-
-
Lakatos, P.L.1
Bajnok, E.2
Tornai, I.3
Folhoffer, A.4
Horvath, A.5
-
23
-
-
27144458524
-
Wnt signalling pathway: a new target for the treatment of osteoporosis
-
Rawadi G, Roman-Roman S, (2005) Wnt signalling pathway: a new target for the treatment of osteoporosis. Expert Opin Ther Targets 9: 1063-1077.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 1063-1077
-
-
Rawadi, G.1
Roman-Roman, S.2
-
24
-
-
41849149688
-
Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
-
Sims AM, Shephard N, Carter K, Doan T, Dowling A, et al. (2008) Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. J Bone Miner Res 23: 499-506.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 499-506
-
-
Sims, A.M.1
Shephard, N.2
Carter, K.3
Doan, T.4
Dowling, A.5
-
25
-
-
0035919656
-
Haplotype variation and linkage disequilibrium in 313 human genes
-
Stephens JC, Schneider JA, Tanguay DA, Choi J, Acharya T, et al. (2001) Haplotype variation and linkage disequilibrium in 313 human genes. Science 293: 489-493.
-
(2001)
Science
, vol.293
, pp. 489-493
-
-
Stephens, J.C.1
Schneider, J.A.2
Tanguay, D.A.3
Choi, J.4
Acharya, T.5
-
26
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA, (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70: 425-434.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
27
-
-
0035679875
-
Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits
-
Deng HW, (2001) Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits. Genetics 159: 1319-1323.
-
(2001)
Genetics
, vol.159
, pp. 1319-1323
-
-
Deng, H.W.1
-
28
-
-
0033926805
-
Association mapping in structured populations
-
Pritchard JK, Stephens M, Rosenberg NA, Donnelly P, (2000) Association mapping in structured populations. AmJHumGenet 67: 170-181.
-
(2000)
AmJHumGenet
, vol.67
, pp. 170-181
-
-
Pritchard, J.K.1
Stephens, M.2
Rosenberg, N.A.3
Donnelly, P.4
-
29
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. NatGenet 38: 904-909.
-
(2006)
NatGenet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
-
30
-
-
67149095078
-
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip
-
Spencer CC, Su Z, Donnelly P, Marchini J, (2009) Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet 5: e1000477.
-
(2009)
PLoS Genet
, vol.5
-
-
Spencer, C.C.1
Su, Z.2
Donnelly, P.3
Marchini, J.4
-
31
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini J, Howie B, Myers S, McVean G, Donnelly P, (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 39: 906-913.
-
(2007)
Nat Genet
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
33
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. AmJHumGenet 81: 559-575.
-
(2007)
AmJHumGenet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
-
34
-
-
61849137254
-
Genome-wide association and replication studies identified TRHR as an important gene for lean body mass
-
Liu XG, Tan LJ, Lei SF, Liu YJ, Shen H, et al. (2009) Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. Am J Hum Genet 84: 418-423.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 418-423
-
-
Liu, X.G.1
Tan, L.J.2
Lei, S.F.3
Liu, Y.J.4
Shen, H.5
|