An antibody to the GM1/GalNAc-GD1a complex correlates with development of pure motor Guillain-Barré syndrome with reversible conduction failure

Journal of Neuroimmunology

Volumn 254, Issue 1-2, 2013, Pages 141-145

  Ogawa, Go ^a   Kaida, Ken Ichi ^a   Kuwahara, Motoi ^b   Kimura, Fumihiko ^a   Kamakura, Keiko ^a   Kusunoki, Susumu ^b  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Conduction block; GalNAc GD1a; Ganglioside complex; GM1; Guillain Barr syndrome

Indexed keywords

GANGLIOSIDE ANTIBODY; GANGLIOSIDE GM1 ANTIBODY; N ACETYLGALACTOSAMINE GANGLIOSIDE GD 1A ANTIBODY; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CRANIAL NEUROPATHY; DISEASE ASSOCIATION; ELECTROPHYSIOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GUILLAIN BARRE SYNDROME; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MOTOR NERVE; NERVE CONDUCTION DISORDER; NERVE FIBER MEMBRANE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REMYELINIZATION; RESPIRATORY TRACT INFECTION; SENSORY DYSFUNCTION; THIN LAYER CHROMATOGRAPHY;

ACTION POTENTIALS; ADULT; AGED; ANTIBODIES; CRANIAL NERVES; ELECTRIC STIMULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; G(M1) GANGLIOSIDE; GANGLIOSIDES; GUILLAIN-BARRE SYNDROME; HUMANS; MALE; MIDDLE AGED; NEURAL CONDUCTION; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84871672642     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.09.005     Document Type: Article

References (22)

1. American Association of Electrodiagnostic Medicine, Olney R.K. Guidelines in electrodiagnostic medicine. Consensus criteria for the diagnosis of partial conduction block. Muscle Nerve 1999, 8:S225-S229.
2. Asbury A.K., Cornblath D.R. Assessment of current diagnostic criteria for Guillain-Barré syndrome. Ann. Neurol. 1990, 27:S21-S24.
3. Capasso M., Caporale C.M., Pomilio F., Gandolfi P., Lugaresi A., Uncini A. Acute motor conduction block neuropathy: another Guillain-Barré syndrome variant. Neurology 2003, 61:617-622.
4. Fernández-Torre J.L., Berciano J., García-Gorostiaga I., Calleja J. Acute motor conduction block neuropathy pattern occurring in the course of an acute inflammatory demyelinating polyradiculoneuropathy. Neurophysiol. Clin. 2008, 38:211-216.
5. Gordon P.H., Wilbourn A.J. Early electrodiagnostic findings in Guillain-Barré syndrome. Arch. Neurol. 2001, 58:913-917.
6. Hadden R.D., Cornblath D.R., Hughes R.A., Zielasek J., Hartung H.P., Toyka K.V., Swan A.V. Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group. Ann. Neurol. 1998, 44:780-788.
7. Hafer-Macko C., Hsieh S.T., Li C.Y., Ho T.W., Sheikh K., Cornblath D.R., McKhann G.M., Asbury A.K., Griffin J.W. Acute motor axonal neuropathy: an antibody-mediated attack on axolemma. Ann. Neurol. 1996, 40:635-644.
8. Hiraga A., Kuwabara S., Ogawara K., Misawa S., Kanesaka T., Koga M., Yuki N., Hattori T., Mori Patterns and serial changes in electrodiagnostic abnormalities of axonal Guillain-Barré syndrome. Neurology 2005, 64:856-860.
9. Ho T.W., Mishu B., Li C.Y., Gao C.Y., Cornblath D.R., Griffin J.W., Asbury A.K., Blaser M.J., McKhann G.M. Guillain-Barré syndrome in northern China. Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies. Brain 1995, 118:597-605.
10. Hong Y.H., Sung J.J., Oh M.Y., Moon H.J., Park K.S., Lee K.W. Axonal conduction block at intermediate nerve segments in pure motor Guillain-Barré syndrome. J. Peripher. Nerv. Syst. 2011, 16:37-46.
11. Hughes R.A., Newsom-Davis J.M., Perkin G.D., Pierce J.M. Controlled trial prednisolone in acute polyneuropathy. Lancet 1978, 2:750-753.
12. Kaida K., Kusunoki S., Kamakura K., Motoyoshi K., Kanazawa I. Guillain-Barré syndrome with antibody to a ganglioside, N-acetylgalactosaminyl GD1a. Brain 2000, 123:116-124.
13. Kaida K., Kusunoki S., Kamakura K., Motoyoshi K., Kanazawa I. GalNAc-GD1a in human peripheral nerve: target sites of anti-ganglioside antibody. Neurology 2003, 61:465-470.
14. Kaida K., Morita D., Kanzaki M., Kamakura K., Motoyoshi K., Hirakawa M., Kusunoki S. Ganglioside complexes: as new target antigens in Guillain-Barré syndrome. Ann. Neurol. 2004, 56:567-571.
15. Kaida K., Morita D., Kanzaki M., Kamakura K., Motoyoshi K., Hirakawa M., Kusunoki S. Anti-ganglioside complex antibodies associated with severe disability in GBS. J. Neuroimmunol. 2007, 182:212-218.
16. Kaida K., Sonoo M., Ogawa G., Kamakura K., Ueda-Sada M., Arita M., Motoyoshi K., Kusunoki S. GM1/GalNAc-GD1a complex: a target for pure motor Guillain-Barré syndrome. Neurology 2008, 71:1683-1690.
17. Kokubun N., Nishibayashi M., Uncini A., Odaka M., Hirata K., Yuki Conduction block in acute motor axonal neuropathy. Brain 2010, 133:2897-2908.
18. Kusunoki S., Chiba A., Kon K., Ando S., Arisawa K., Tate A., Kanazawa I. N-acetylgalactosaminyl GD1a is a target molecule for serum antibody in Guillain-Barré syndrome. Ann. Neurol. 1994, 35:570-576.
19. Kuwabara S., Yuki N., Koga M., Hattori T., Matsuura D., Miyake M., Noda M. IgG anti-GM1 antibody is associated with reversible conduction failure and axonal degeneration in Guillain-Barré syndrome. Ann. Neurol. 1998, 44:202-208.
20. Ogawa G., Kaida K., Shiozaki Y., Araki M., Kimura F., Kamakura K. Case of pure motor Guillain-Barré syndrome with motor conduction block and anti-GM1/GalNAc-GD1a antibody. Rinsho Shinkeigaku 2009, 49:488-492.
21. Sugie K., Murata K., Ikoma K., Suzumura A., Takayanagi T. A case of acute multifocal motor neuropathy with conduction block after Campylobacter jejuni enteritis. Rinsho Shinkeigaku 1998, 38:42-45.
22. Yuki N., Susuki K., Koga M., Nishimoto Y., Odaka M., Hirata K., Taguchi K., Miyatake T., Furukawa K., Kobata T., Yamada Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:11404-11409.