Common polymorphisms in the CYP11B1 and CYP11B2 genes: Evidence for a digenic influence on hypertension

Hypertension

Volumn 61, Issue 1, 2013, Pages 232-239

  Alvarez Madrazo, Samantha ^a   MacKenzie, Scott M ^a   Davies, Eleanor ^a   Fraser, Robert ^a   Lee, Wai Kwong ^a   Brown, Morris ^b   Caulfield, Mark J ^c   Dominiczak, Anna F ^a   Farrall, Martin ^d   Lathrop, Mark ^e   Hedner, Thomas ^f   Melander, Olle ^g   Munroe, Patricia B ^c   Samani, Nilesh ^h   Stewart, Paul M ⁱ   Wahlstrand, Björn ^f   Webster, John ^j   Palmer, Colin N A ^k   Padmanabhan, Sandosh ^a   Connell, John M ^k  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^f UNIVERSITY OF GOTHENBURG   (Sweden)

^g LUND UNIVERSITY   (Sweden)

^h UNIVERSITY OF LEICESTER   (United Kingdom)

ⁱ UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^j ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^k UNIVERSITY OF DUNDEE   (United Kingdom)

more..

Author keywords

aldosterone; cortisol; CYP11B1; CYP11B2; haplotypes; hypertension; population

Indexed keywords

ALDOSTERONE SYNTHASE; STEROID 11BETA MONOOXYGENASE;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; HAPLOTYPE; HUMAN; HUMAN TISSUE; HYPERTENSION; INTRON; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADRENAL GLANDS; ADULT; AGED; ALDOSTERONE SYNTHASE; ALLELES; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; HAPLOTYPES; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; STEROID 11-BETA-HYDROXYLASE;

EID: 84871620553     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.200741     Document Type: Article

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