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Volumn 461, Issue 5, 2012, Pages 521-530

HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma

Author keywords

Bile duct; Cholangiocarcinoma; Extrahepatic; HER2; HER3; Immunohistochemistry; Prognosis

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3;

EID: 84871615188     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-012-1321-0     Document Type: Article
Times cited : (23)

References (62)
  • 1
    • 33750491929 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Modern advances in understanding a deadly old disease
    • DOI 10.1016/j.jhep.2006.09.001, PII S0168827806004910
    • Malhi H, Gores GJ (2006) Cholangiocarcinoma: modern advances in understanding a deadly old disease. J Hepatol 45:856-867 (Pubitemid 44646688)
    • (2006) Journal of Hepatology , vol.45 , Issue.6 , pp. 856-867
    • Malhi, H.1    Gores, G.J.2
  • 2
    • 23444431756 scopus 로고    scopus 로고
    • Analysis of extrahepatic bile duct carcinomas according to the new American Joint Committee on Cancer staging system focused on tumor classification problems in 222 patients
    • DOI 10.1002/cncr.21236
    • Hong SM, Kim MJ, Pi DY, Jo D, Cho HJ, Yu E, Ro JY (2005) Analysis of extrahepatic bile duct carcinomas according to the New American Joint Committee on Cancer staging system focused on tumor classification problems in 222 patients. Cancer 104:802-810 (Pubitemid 41113681)
    • (2005) Cancer , vol.104 , Issue.4 , pp. 802-810
    • Hong, S.-M.1    Kim, M.-J.2    Pi, D.Y.3    Jo, D.4    Cho, H.J.5    Yu, E.6    Ro, J.Y.7
  • 4
    • 34247641098 scopus 로고    scopus 로고
    • Current surgical treatment for bile duct cancer
    • Seyama Y, Makuuchi M (2007) Current surgical treatment for bile duct cancer. World J Gastroenterol 13:1505-1515 (Pubitemid 46672657)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.10 , pp. 1505-1515
    • Seyama, Y.1    Makuuchi, M.2
  • 5
    • 35148866287 scopus 로고    scopus 로고
    • Trends in survival after surgery for cholangiocarcinoma: A 30-year population-based SEER database analysis
    • discussion 1496-1487
    • Nathan H, Pawlik TM, Wolfgang CL, Choti MA, Cameron JL, Schulick RD (2007) Trends in survival after surgery for cholangiocarcinoma: a 30-year population-based SEER database analysis. J Gastrointest Surg 11:1488-1496, discussion 1496-1487
    • (2007) J Gastrointest Surg , vol.11 , pp. 1488-1496
    • Nathan, H.1    Pawlik, T.M.2    Wolfgang, C.L.3    Choti, M.A.4    Cameron, J.L.5    Schulick, R.D.6
  • 6
    • 33845296152 scopus 로고    scopus 로고
    • Biological characteristics of cancers in the gallbladder and biliary tract and targeted therapy
    • DOI 10.1016/j.critrevonc.2006.07.006, PII S1040842806001594
    • Thomas MB (2007) Biological characteristics of cancers in the gallbladder and biliary tract and targeted therapy. Crit Rev Oncol Hematol 61:44-51 (Pubitemid 44880150)
    • (2007) Critical Reviews in Oncology/Hematology , vol.61 , Issue.1 , pp. 44-51
    • Thomas, M.B.1
  • 7
    • 44949141721 scopus 로고    scopus 로고
    • The ERBB3 receptor in cancer and cancer gene therapy
    • DOI 10.1038/cgt.2008.15, PII CGT200815
    • Sithanandam G, Anderson LM (2008) The ERBB3 receptor in cancer and cancer gene therapy. Cancer Gene Ther 15:413-448 (Pubitemid 351822188)
    • (2008) Cancer Gene Therapy , vol.15 , Issue.7 , pp. 413-448
    • Sithanandam, G.1    Anderson, L.M.2
  • 9
    • 33745828702 scopus 로고    scopus 로고
    • EGF-ERBB signalling: Towards the systems level
    • DOI 10.1038/nrm1962, PII NRM1962
    • Citri A, Yarden Y (2006) EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 7:505-516 (Pubitemid 44036456)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.7 , pp. 505-516
    • Citri, A.1    Yarden, Y.2
  • 10
    • 34547871259 scopus 로고    scopus 로고
    • Targeting HER proteins in cancer therapy and the role of the non-target HER3
    • DOI 10.1038/sj.bjc.6603910, PII 6603910
    • Hsieh AC, Moasser MM (2007) Targeting HER proteins in cancer therapy and the role of the non-target HER3. Br J Cancer 97:453-457 (Pubitemid 47258458)
    • (2007) British Journal of Cancer , vol.97 , Issue.4 , pp. 453-457
    • Hsieh, A.C.1    Moasser, M.M.2
  • 11
    • 0026454327 scopus 로고
    • Production and characterization of a polyclonal antibody to the c-erbB-3 protein: Examination of c-erbB-3 protein expression in adenocarcinomas
    • Poller DN, Spendlove I, Baker C, Church R, Ellis IO, Plowman GD, Mayer RJ (1992) Production and characterization of a polyclonal antibody to the c-erbB-3 protein: examination of c-erbB-3 protein expression in adenocarcinomas. J Pathol 168:275-280
    • (1992) J Pathol , vol.168 , pp. 275-280
    • Poller, D.N.1    Spendlove, I.2    Baker, C.3    Church, R.4    Ellis, I.O.5    Plowman, G.D.6    Mayer, R.J.7
  • 13
    • 0031865433 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor family proteins (EGFR, c-erbB-2 and c-erbB-3) in gastric cancer and chronic gastritis
    • Slesak B, Harlozinska A, Porebska I, Bojarowski T, Lapinska J, Rzeszutko M, Wojnar A (1998) Expression of epidermal growth factor receptor family proteins (EGFR, c-erbB-2 and c-erbB-3) in gastric cancer and chronic gastritis. Anticancer Res 18:2727-2732 (Pubitemid 28386573)
    • (1998) Anticancer Research , vol.18 , Issue.4 , pp. 2727-2732
    • Slesak, B.1    Harlozinska, A.2    Porebska, I.3    Bojarowski, T.4    Lapinska, J.5    Rzeszutko, M.6    Wojnar, A.7
  • 15
    • 0031928378 scopus 로고    scopus 로고
    • Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2
    • DOI 10.1016/S0046-8177(98)90444-0
    • Maurer CA, Friess H, Kretschmann B, Zimmermann A, Stauffer A, Baer HU, Korc M, Buchler MW (1998) Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2. Hum Pathol 29:771-777 (Pubitemid 28375981)
    • (1998) Human Pathology , vol.29 , Issue.8 , pp. 771-777
    • Maurer, C.A.1    Friess, H.2    Kretschmann, B.3    Zimmermann, A.4    Stauffer, A.5    Baer, H.U.6    Korc, M.7    Buchler, M.W.8
  • 18
    • 0033497861 scopus 로고    scopus 로고
    • Growth factor receptors are differentially expressed in cancers of the papilla of Vater and pancreas
    • discussion 774-765
    • Friess H, Wang L, Zhu Z, Gerber R, Schroder M, Fukuda A, Zimmermann A, Korc M, Buchler MW (1999) Growth factor receptors are differentially expressed in cancers of the papilla of Vater and pancreas. Ann Surg 230:767-774, discussion 774-765
    • (1999) Ann Surg , vol.230 , pp. 767-774
    • Friess, H.1    Wang, L.2    Zhu, Z.3    Gerber, R.4    Schroder, M.5    Fukuda, A.6    Zimmermann, A.7    Korc, M.8    Buchler, M.W.9
  • 19
    • 0028799821 scopus 로고
    • Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression
    • Friess H, Yamanaka Y, Kobrin MS, Do DA, Buchler MW, Korc M (1995) Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression. Clin Cancer Res 1:1413-1420
    • (1995) Clin Cancer Res , vol.1 , pp. 1413-1420
    • Friess, H.1    Yamanaka, Y.2    Kobrin, M.S.3    Do, D.A.4    Buchler, M.W.5    Korc, M.6
  • 20
    • 38549139744 scopus 로고    scopus 로고
    • Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
    • DOI 10.1038/sj.bjc.6604129, PII 6604129
    • Yoshikawa D, Ojima H, Iwasaki M, Hiraoka N, Kosuge T, Kasai S, Hirohashi S, Shibata T (2008) Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. Br J Cancer 98:418-425 (Pubitemid 351161240)
    • (2008) British Journal of Cancer , vol.98 , Issue.2 , pp. 418-425
    • Yoshikawa, D.1    Ojima, H.2    Iwasaki, M.3    Hiraoka, N.4    Kosuge, T.5    Kasai, S.6    Hirohashi, S.7    Shibata, T.8
  • 21
    • 0034941321 scopus 로고    scopus 로고
    • Expression of oncogene products HER2/Neu and Ras and fibrosisrelated growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders
    • Su WC, Shiesh SC, Liu HS, Chen CY, Chow NH, Lin XZ (2001) Expression of oncogene products HER2/Neu and Ras and fibrosisrelated growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disorders. Dig Dis Sci 46:1387-1392
    • (2001) Dig Dis Sci , vol.46 , pp. 1387-1392
    • Su, W.C.1    Shiesh, S.C.2    Liu, H.S.3    Chen, C.Y.4    Chow, N.H.5    Lin, X.Z.6
  • 23
    • 77649339494 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder
    • Shafizadeh N, Grenert JP, Sahai V, Kakar S (2010) Epidermal growth factor receptor and HER-2/neu status by immunohistochemistry and fluorescence in situ hybridization in adenocarcinomas of the biliary tree and gallbladder. Hum Pathol 41:485-492
    • (2010) Hum Pathol , vol.41 , pp. 485-492
    • Shafizadeh, N.1    Grenert, J.P.2    Sahai, V.3    Kakar, S.4
  • 24
    • 59449103646 scopus 로고    scopus 로고
    • The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma
    • Chung JY, Hong SM, Choi BY, Cho H, Yu E, Hewitt SM (2009) The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma. Clin Cancer Res 15:660-667
    • (2009) Clin Cancer Res , vol.15 , pp. 660-667
    • Chung, J.Y.1    Hong, S.M.2    Choi, B.Y.3    Cho, H.4    Yu, E.5    Hewitt, S.M.6
  • 25
    • 79960885569 scopus 로고    scopus 로고
    • Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma
    • doi:1479-5876-9-126
    • Takikita M, Xie R, Chung JY, Cho H, Ylaya K, Hong SM, Moskaluk CA, Hewitt SM (2011) Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma. J Transl Med 9:126. doi:1479-5876-9-126
    • (2011) J Transl Med , vol.9 , pp. 126-126
    • Takikita, M.1    Xie, R.2    Chung, J.Y.3    Cho, H.4    Ylaya, K.5    Hong, S.M.6    Moskaluk, C.A.7    Hewitt, S.M.8
  • 28
    • 0028216712 scopus 로고
    • Identification of c-erbB-3 binding sites for phosphatidylinositol 3′-kinase and SHC using an EGF receptor/c-erbB-3 chimera
    • Prigent SA, Gullick WJ (1994) Identification of c-erbB-3 binding sites for phosphatidylinositol 3′-kinase and SHC using an EGF receptor/c-erbB-3 chimera. EMBO J 13:2831-2841
    • (1994) EMBO J , vol.13 , pp. 2831-2841
    • Prigent, S.A.1    Gullick, W.J.2
  • 32
    • 33846552656 scopus 로고    scopus 로고
    • Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3
    • DOI 10.1038/nature05474, PII NATURE05474
    • Sergina NV, Rausch M, Wang D, Blair J, Hann B, Shokat KM, Moasser MM (2007) Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3. Nature 445:437-441 (Pubitemid 46160912)
    • (2007) Nature , vol.445 , Issue.7126 , pp. 437-441
    • Sergina, N.V.1    Rausch, M.2    Wang, D.3    Blair, J.4    Hann, B.5    Shokat, K.M.6    Moasser, M.M.7
  • 35
    • 25444492850 scopus 로고    scopus 로고
    • Dual activation of pathways regulated by steroid receptors and peptide growth factors in primary prostate cancer revealed by factor analysis of microarray data
    • doi:1471-2164-6-109
    • Lozano JJ, Soler M, Bermudo R, Abia D, Fernandez PL, Thomson TM, Ortiz AR (2005) Dual activation of pathways regulated by steroid receptors and peptide growth factors in primary prostate cancer revealed by factor analysis of microarray data. BMC Genomics 6:109. doi:1471-2164-6-109
    • (2005) BMC Genomics , vol.6 , pp. 109
    • Lozano, J.J.1    Soler, M.2    Bermudo, R.3    Abia, D.4    Fernandez, P.L.5    Thomson, T.M.6    Ortiz, A.R.7
  • 38
    • 80051647503 scopus 로고    scopus 로고
    • Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome
    • Begnami MD, Fukuda E, Fregnani JH, Nonogaki S, Montagnini AL, da Costa WL, Soares FA Jr (2011) Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome. J Clin Oncol 29:3030-3036
    • (2011) J Clin Oncol , vol.29 , pp. 3030-3036
    • Begnami, M.D.1    Fukuda, E.2    Fregnani, J.H.3    Nonogaki, S.4    Montagnini, A.L.5    Da Costa, W.L.6    Soares Jr., F.A.7
  • 39
    • 0031046064 scopus 로고    scopus 로고
    • High c-erbB-3 protein expression is associated with shorter survival in advanced non-small cell lung carcinomas
    • Yi ES, Harclerode D, Gondo M, Stephenson M, Brown RW, Younes M, Cagle PT (1997) High c-erbB-3 protein expression is associated with shorter survival in advanced non-small cell lung carcinomas. Mod Pathol 10:142-148 (Pubitemid 27110039)
    • (1997) Modern Pathology , vol.10 , Issue.2 , pp. 142-148
    • Yi, E.S.1    Harclerode, D.2    Gondo, M.3    Stephenson, M.4    Brown, R.W.5    Younes, M.6    Cagle, P.T.7
  • 40
    • 3042797636 scopus 로고    scopus 로고
    • Her2/neu is not a commonly expressed therapeutic target in melanoma - A large cohort tissue microarray study
    • DOI 10.1097/01.cmr.0000130874.33504.2f
    • Kluger HM, DiVito K, Berger AJ, Halaban R, Ariyan S, Camp RL, Rimm DL (2004) Her2/neu is not a commonly expressed therapeutic target in melanoma - a large cohort tissue microarray study. Melanoma Res 14:207-210 (Pubitemid 38879583)
    • (2004) Melanoma Research , vol.14 , Issue.3 , pp. 207-210
    • Kluger, H.M.1    Divito, K.2    Berger, A.J.3    Halaban, R.4    Ariyan, S.5    Camp, R.L.6    Rimm, D.L.7
  • 41
    • 44949117528 scopus 로고    scopus 로고
    • Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells
    • DOI 10.1002/ijc.23465
    • Ueno Y, Sakurai H, Tsunoda S, Choo MK, Matsuo M, Koizumi K, Saiki I (2008) Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells. Int J Cancer 123:340-347 (Pubitemid 351842018)
    • (2008) International Journal of Cancer , vol.123 , Issue.2 , pp. 340-347
    • Ueno, Y.1    Sakurai, H.2    Tsunoda, S.3    Choo, M.-K.4    Matsuo, M.5    Koizumi, K.6    Saiki, I.7
  • 44
    • 3042563755 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: Appraisal of an animal model of cholangiocarcinoma
    • Jan YY, Yeh TS, Yeh JN, Yang HR, Chen MF (2004) Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma. Ann Surg 240:89-94
    • (2004) Ann Surg , vol.240 , pp. 89-94
    • Jan, Y.Y.1    Yeh, T.S.2    Yeh, J.N.3    Yang, H.R.4    Chen, M.F.5
  • 45
    • 21344438897 scopus 로고    scopus 로고
    • Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers
    • DOI 10.1002/path.1779
    • Nakazawa K, Dobashi Y, Suzuki S, Fujii H, Takeda Y, Ooi A (2005) Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol 206:356-365 (Pubitemid 40903200)
    • (2005) Journal of Pathology , vol.206 , Issue.3 , pp. 356-365
    • Nakazawa, K.1    Dobashi, Y.2    Suzuki, S.3    Fujii, H.4    Takeda, Y.5    Ooi, A.6
  • 48
    • 37049013090 scopus 로고    scopus 로고
    • Cetuximab plus gemcitabine-oxaliplatin (GEMOX) in patients with refractory advanced intrahepatic cholangiocarcinomas
    • DOI 10.1159/000111117
    • Paule B, Herelle MO, Rage E, Ducreux M, Adam R, Guettier C, Bralet MP (2007) Cetuximab plus gemcitabine-oxaliplatin (GEMOX) in patients with refractory advanced intrahepatic cholangiocarcinomas. Oncology 72:105-110 (Pubitemid 350249137)
    • (2007) Oncology , vol.72 , Issue.1-2 , pp. 105-110
    • Paule, B.1    Herelle, M.-O.2    Rage, E.3    Ducreux, M.4    Adam, R.5    Guettier, C.6    Bralet, M.-P.7
  • 51
    • 0036124041 scopus 로고    scopus 로고
    • C-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma
    • DOI 10.1046/j.1365-2559.2002.00353.x
    • Aishima SI, Taguchi KI, Sugimachi K, Shimada M, Tsuneyoshi M (2002) c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma. Histopathology 40:269-278 (Pubitemid 34227118)
    • (2002) Histopathology , vol.40 , Issue.3 , pp. 269-278
    • Aishima, S.-I.1    Taguchi, K.-I.2    Sugimachi, K.3    Shimada, M.4    Sugimachi, K.5    Tsuneyoshi, M.6
  • 53
    • 0028869784 scopus 로고
    • Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract
    • Chow NH, Huang SM, Chan SH, Mo LR, Hwang MH, Su WC (1995) Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract. Anticancer Res 15:1055-1059
    • (1995) Anticancer Res , vol.15 , pp. 1055-1059
    • Chow, N.H.1    Huang, S.M.2    Chan, S.H.3    Mo, L.R.4    Hwang, M.H.5    Su, W.C.6
  • 54
    • 0036322129 scopus 로고    scopus 로고
    • ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions
    • DOI 10.1053/jhep.2002.34435
    • Endo K, Yoon BI, Pairojkul C, Demetris AJ, Sirica AE (2002) ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions. Hepatology 36:439-450 (Pubitemid 34810365)
    • (2002) Hepatology , vol.36 , Issue.2 , pp. 439-450
    • Endo, K.1    Yoon, B.-I.2    Pairojkul, C.3    Demetris, A.J.4    Sirica, A.E.5
  • 56
    • 0036623359 scopus 로고    scopus 로고
    • Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry
    • DOI 10.1016/S0168-8278(02)00057-0, PII S0168827802000570
    • Ukita Y, Kato M, Terada T (2002) Gene amplification and mRNA and protein overexpression of c-erbB-2 (HER-2/neu) in human intrahepatic cholangiocarcinoma as detected by fluorescence in situ hybridization, in situ hybridization, and immunohistochemistry. J Hepatol 36:780-785 (Pubitemid 35177407)
    • (2002) Journal of Hepatology , vol.36 , Issue.6 , pp. 780-785
    • Ukita, Y.1    Kato, M.2    Terada, T.3
  • 57
    • 0024843763 scopus 로고
    • Oncogene expression in cholangiocarcinoma and in normal hepatic development
    • Voravud N, Foster CS, Gilbertson JA, Sikora K, Waxman J (1989) Oncogene expression in cholangiocarcinoma and in normal hepatic development. Hum Pathol 20:1163-1168 (Pubitemid 20034145)
    • (1989) Human Pathology , vol.20 , Issue.12 , pp. 1163-1168
    • Voravud, N.1    Foster, C.S.2    Gilbertson, J.A.3    Sikora, K.4    Waxman, J.5
  • 61
    • 0035312199 scopus 로고    scopus 로고
    • Differing rates of loss of Dpc4 expression and of p53 overexpression among carcinomas of the proximal and distal bile ducts evidence for a biologic distinction
    • DOI 10.1002/1097-0142(20010401)91:7<1332::AID-CNCR1136>3.0.CO;2-4
    • Argani P, Shaukat A, Kaushal M, Wilentz RE, Su GH, Sohn TA, Yeo CJ, Cameron JL, Kern SE, Hruban RH (2001) Differing rates of loss of DPC4 expression and of p53 overexpression among carcinomas of the proximal and distal bile ducts. Cancer 91:1332-1341 (Pubitemid 32267045)
    • (2001) Cancer , vol.91 , Issue.7 , pp. 1332-1341
    • Argani, P.1    Shaukat, A.2    Kaushal, M.3    Wilentz, R.E.4    Su, G.H.5    Sohn, T.A.6    Yeo, C.J.7    Cameron, J.L.8    Kern, S.E.9    Hruban, R.H.10


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