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Volumn 10, Issue 1, 2013, Pages 5-6

Skin cancer: Targeted therapy for melanoma: Is double hitting a home run?

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE INHIBITOR; DABRAFENIB; TRAMETINIB; VEMURAFENIB; ANTINEOPLASTIC AGENT; B RAF KINASE; BRAF PROTEIN, HUMAN; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

EID: 84871611623     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2012.215     Document Type: Note
Times cited : (10)

References (10)
  • 1
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    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman, P. B. et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364, 2507-316 (2011).
    • (2011) N. Engl. J. Med , vol.364 , pp. 2507-3316
    • Chapman, P.B.1
  • 2
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
    • Hauschild, A. et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 380, 358-365 (2012).
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1
  • 3
    • 84862908097 scopus 로고    scopus 로고
    • RAS Mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors
    • Su, F. et al. RAS Mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N. Engl. J. Med. 366, 207-215 (2012).
    • (2012) N. Engl. J. Med , vol.366 , pp. 207-215
    • Su, F.1
  • 4
    • 77953276524 scopus 로고    scopus 로고
    • Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy
    • Paraiso, K. H. et al. Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy. Br. J. Cancer 102, 1724-1730 (2010).
    • (2010) Br. J. Cancer , vol.102 , pp. 1724-1730
    • Paraiso, K.H.1
  • 5
    • 84863673204 scopus 로고    scopus 로고
    • Improved survival with MEK inhibition in BRAF-mutated melanoma
    • Flaherty, K. T. et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N. Engl. J. Med. 367, 107-114 (2012).
    • (2012) N. Engl. J. Med , vol.367 , pp. 107-114
    • Flaherty, K.T.1
  • 6
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
    • Flaherty, K. T. et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N. Engl. J. Med. 367, 1694-1703 (2012).
    • (2012) N. Engl. J. Med , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1
  • 7
    • 84871611106 scopus 로고    scopus 로고
    • Development of colonic adenomas and gastric polyps in BRAF mutant melanoma patients treated with vemurafenib [abstract]
    • Chapman, P. B. et al. Development of colonic adenomas and gastric polyps in BRAF mutant melanoma patients treated with vemurafenib [abstract]. Pigment Cell Melanoma Res. 25, 847 (2012).
    • (2012) Pigment Cell Melanoma Res , vol.25 , pp. 847
    • Chapman, P.B.1
  • 8
    • 84871037064 scopus 로고    scopus 로고
    • Progression of RAS-mutant leukemia during RAF inhibitor treatment
    • doi:10.1056/NEJMoa1208958
    • Callahan, M. et al. Progression of RAS-mutant leukemia during RAF inhibitor treatment. N. Engl. J. Med. doi:10.1056/NEJMoa1208958.
    • N. Engl. J. Med
    • Callahan, M.1
  • 9
    • 84871611114 scopus 로고    scopus 로고
    • Colorectal cancer promoted in a melanoma patient receiving dabrafenib (GSK2118436) in combination with MEK1/2 inhibitor trametinib (GSK1120212) [abstract]
    • Andrews, M. et al. Colorectal cancer promoted in a melanoma patient receiving dabrafenib (GSK2118436) in combination with MEK1/2 inhibitor trametinib (GSK1120212) [abstract]. Pigment Cell Melanoma Res. 25, 842 (2012).
    • (2012) Pigment Cell Melanoma Res , vol.25 , pp. 842
    • Andrews, M.1
  • 10
    • 84857073184 scopus 로고    scopus 로고
    • Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438)
    • Margolin, K. A. et al. Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438). Clin. Cancer Res. 18, 1129-1137 (2012).
    • (2012) Clin. Cancer Res. , vol.18 , pp. 1129-1137
    • Margolin, K.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.