Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation

Prostate

Volumn 73, Issue 2, 2013, Pages 133-145

  Yu, Chia Chun ^a   Wu, Ping Jung ^a   Hsu, Jui Ling ^a   Ho, Yunn Fang ^a   Hsu, Lih Ching ^a   Chang, Yu Jia ^b   Chang, Hsun Shuo ^c   Chen, Ih Sheng ^c   Guh, Jih Hwa ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

AIF; ardisianone; ER stress; mitochondrial damage stress; survivin

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; ARDISIANONE; BENZOQUINONE DERIVATIVE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SURVIVIN; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BENZOQUINONES; CELL LINE, TUMOR; DOWN-REGULATION; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 84871610611     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22548     Document Type: Article

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