Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43527-43532

  Gottschalk, Aaron J ^a   Trivedi, Rushi D ^a,b   Conaway, Joan W ^a,b   Conaway, Ronald C ^a,b  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADP-RIBOSE; ALLOSTERIC EFFECTORS; FOOTPRINTING; NUCLEOSOME REMODELING; NUCLEOSOMES; POLY(ADP-RIBOSE);

BIOCHEMISTRY;

BIOLOGY;

AMPLIFIED IN LIVER CANCER 1 PROTEIN; DNA BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; ENZYME ACTIVITY; MOLECULAR STABILITY; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA HELICASES; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; NAD; NUCLEOSOMES; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES;

EID: 84871605560     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.401141     Document Type: Article

References (15)

1. Ma, N. F., Hu, L., Fung, J. M., Xie, D., Zheng, B. J., Chen, L., Tang, D. J., Fu, L., Wu, Z., Chen, M., Fang, Y., and Guan, X. Y. (2008) Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. Hepatology 47, 503-510 (Pubitemid 351280718)
2. Chen, M., Huang, J. D., Hu, L., Zheng, B. J., Chen, L., Tsang, S. L., and Guan, X. Y. (2009) Transgenic CHD1L expression in mouse induces spontaneous tumors. PLoS ONE 4, e6727
3. Brockschmidt, A., Chung, B., Weber, S., Fischer, D. C., Kolatsi-Joannou, M., Christ, L., Heimbach, A., Shtiza, D., Klaus, G., Simonetti, G. D., Konrad, M., Winyard, P., Haffner, D., Schaefer, F., and Weber, R. G. (2012) CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT). Nephrol. Dial. Transplant. 27, 2355-2364
4. Ahel, D., Horejsí, Z., Wiechens, N., Polo, S. E., Garcia-Wilson, E., Ahel, I., Flynn, H., Skehel, M., West, S. C., Jackson, S. P., Owen-Hughes, T., and Boulton, S. J. (2009) Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science 325, 1240-1243
5. Chen, L., Chan, T. H., Yuan, Y. F., Hu, L., Huang, J., Ma, S., Wang, J., Dong, S. S., Tang, K. H., Xie, D., Li, Y., and Guan, X. Y. (2010) CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J. Clin. Invest. 120, 1178-1191
6. Gottschalk, A. J., Timinszky, G., Kong, S. E., Jin, J., Cai, Y., Swanson, S. K., Washburn, M. P., Florens, L., Ladurner, A. G., Conaway, J. W., and Conaway, R. C. (2009) Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proc. Natl. Acad. Sci. U.S.A. 106, 13770-13774
7. Owen-Hughes, T., Utley, R. T., Steger, D. J., West, J. M., John, S., Côté, J., Havas, K. M., and Workman, J. L. (1999) Analysis of nucleosome disruption by ATP-driven chromatin remodeling complexes. Methods Mol. Biol. 119, 319-331
8. Gutiérrez, J. L., Chandy, M., Carrozza, M. J., and Workman, J. L. (2007) Activation domains drive nucleosome eviction by SWI/SNF. EMBO J. 26, 730-740
9. Purnell, M. R., and Whish, W. J. (1980) Novel inhibitors of poly(ADP-ribose) synthetase. Biochem. J. 185, 775-777
10. D'Amours, D., Desnoyers, S., D'Silva, I., and Poirier, G. G. (1999) Poly-(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342, 249-268 (Pubitemid 29425344)
11. + into a nuclear signal. Genes Dev. 19, 1951-1967
12. Miwa, M., Tanaka, M., Matsushima, T., and Sugimura, T. (1974) Purification and properties of glycohydrolase from calf thymus splitting ribose-ribose linkages of poly(adenosine diphosphate ribose). J. Biol. Chem. 249, 3475-3482
13. Kim, I. K., Kiefer, J. R., Ho, C. M., Stegeman, R. A., Classen, S., Tainer, J. A., and Ellenberger, T. (2012) Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element. Nat. Struct. Mol. Biol. 19, 653-656
14. +-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell 119, 803-814
15. Timinszky, G., Till, S., Hassa, P. O., Hothorn, M., Kustatscher, G., Nijmeijer, B., Colombelli, J., Altmeyer, M., Stelzer, E. H., Scheffzek, K., Hottiger, M. O., and Ladurner, A. G. (2009) A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat. Struct. Mol. Biol. 16, 923-929