Personalization of antimicrobial dosing regimens: Indicators of performance

Italian Journal of Public Health

Volumn 9, Issue 4, 2012, Pages

  Pea, Federico ^a   Cojutti, Piergiorgio ^a   Dose, Lucia ^a   Furian, Cristina ^a   Guarrera, Giovanni ^a   Furlanut, Mario ^a  

^a SANTA MARIA DELLA MISERICORDIA UNIVERSITY HOSPITAL   (Italy)

Author keywords

Clinical pharmacological advice; Personalized antimicrobial therapy; Therapeutic drug monitoring

Indexed keywords

EID: 84871599160     PISSN: 17237815     EISSN: None     Source Type: Journal    
DOI: 10.2427/8668     Document Type: Article

References (12)

1. Birkett D, Brosen K, Cascorbi I, et al. Clinical pharmacology in research, teaching and health care: Considerations by IUPHAR, the International Union of Basic and Clinical Pharmacology. Basic Clin Pharmacol Toxicol 2010; 107(1): 531-559
2. Llorente Fernandez E, Pares L, Ajuria I, et al. State of the art in therapeutic drug monitoring. Clin Chem Lab Med 2010; 48(4): 437-46
3. Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008; 34(1): 17-60
4. Roberts JA, Norris R, Paterson DL, et al. Therapeutic drug monitoring of antimicrobials. Br J Clin Pharmacol 2012;73(1): 27-36
5. Daniels R. Surviving the first hours in sepsis: getting the basics right (an intensivist's perspective). J Antimicrob Chemother 2011; 66 Suppl 2: ii11-ii23
6. Alvarez-Lerma F, Grau S. Management of antimicrobial use in the intensive care unit. Drugs 2012; 72(4): 447-70
7. Udy AA, Varghese JM, Altukroni M, et al. Subtherapeutic initial beta-lactam concentrations in select critically ill patients: association between augmented renal clearance and low trough drug concentrations. Chest. 2012; 142(1): 30-9
8. Pea F, Viale P. The antimicrobial therapy puzzle: could pharmacokinetic-pharmacodynamic relationships be helpful in addressing the issue of appropriate pneumonia treatment in critically ill patients? Clin Infect Dis 2006; 42(12): 1764-71
9. Pea F, Viale P. Bench-to-bedside review: Appropriate antibiotic therapy in severe sepsis and septic shock--does the dose matter? Crit Care 2009; 13(3): 214
10. Roberts JA, Hope WW, Lipman J. Therapeutic drug monitoring of beta-lactams for critically ill patients: unwarranted or essential? Int J Antimicrob Agents 2010; 35(5): 419-20
11. Touw DJ, Neef C, Thomson AH, et al. Costeffectiveness of therapeutic drug monitoring: a systematic review. Ther Drug Monit 2005; 27(1): 10-7
12. Dellit TH, Owens RC, McGowan JE Jr., et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007; 44(2): 159-77