Gold-catalyzed domino cycloisomerization/pictet-spengler reaction of 2-(4-aminobut-1-yn-1-yl)anilines with aldehydes: Synthesis of tetrahydropyrido[4,3-b ]indole scaffolds

Journal of Organic Chemistry

Volumn 77, Issue 24, 2012, Pages 11355-11361

  Subba Reddy, B V ^a   Swain, Manisha ^a   Reddy, S Madhusudana ^a   Yadav, J S ^a   Sridhar, B ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC SYSTEM; CYCLOISOMERIZATIONS; INDOLE DERIVATIVES;

ALDEHYDES; ANILINE; ORGANIC COMPOUNDS; SCAFFOLDS;

CYCLIZATION;

1 (2 BROMOPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (2 FLUOROPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (2,4 DICHLOROPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 (3,4 DIMETHOXYPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO [4,3 B]INDOLE; 1 (3,5 DIMETHYLPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 (4 BROMOPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (4 CHLOROPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (4 FLUOROPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (4 METHOXYPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 (4 NITROPHENYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (NAPHTHALEN 1 YL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B] INDOLE; 1 (NAPHTHALEN 2 YL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4, 3 B] INDOLE; 1 (O TOLYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 (P CHLOROPHENYL) 8 METHOXY 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDOL[4,3 B]INDOLE; 1 (P TOLYL) 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 CYCLOHEXYL 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 PHENYL 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 1 STYRYL 2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOLE; 2 (4 AMINOBUT 1 YN 1 YL)ANILINE; 2 BROMO 4 (2 TOSYL 2,3,4,5 TETRAHYDRO 1H PYRIDO[4,3 B]INDOL 1 YL)PHENOL; ALDEHYDE; ANILINE DERIVATIVE; INDOLE; INDOLE DERIVATIVE; N (2 (1H INDOL 2 YL)ETHYL) 4 METHYLBENZENESULFONAMIDE; N (4 (2 AMINO 5 METHOXYPHENYL)BUT 3 YN 1 YL) 4 METHYL BENZENESULFONAMIDE; N (BUT 3 YN 1 YL) 4 METHYLBENZENESULFONAMIDE; TETRAHYDROPYRIDO[4,3 B]INDOLE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERIZATION;

ALDEHYDES; ANILINE COMPOUNDS; CATALYSIS; CHEMISTRY TECHNIQUES, SYNTHETIC; CYCLIZATION; GOLD; INDOLES; ISOMERISM;

EID: 84871587865     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo302068e     Document Type: Article

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