Reversible left ventricular dysfunction and acute kidney injury in a patient with nonamyloid light chain deposition disease

Clinical Nephrology

Volumn 78, Issue 6, 2012, Pages 501-505

  Wadhwa, Nand K ^a   Kamra, Amit ^a   Skopicki, Hal A ^a   Richard, Shambavi ^a   Miller, Frederick ^a   Nord, Edward P ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Acute kidney injury; Autologous stem cell transplant; Left ventricular dysfunction; Nephrotic syndrome; Non amyloid light chain deposition disease

Indexed keywords

BETA 2 MICROGLOBULIN; BORTEZOMIB; CREATININE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; FUROSEMIDE; METOPROLOL SUCCINATE; QUINAPRIL; SPIRONOLACTONE;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BONE MARROW BIOPSY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; LIGHT CHAIN DEPOSITION DISEASE; NON AMYLOID LIGHT CHAIN DEPOSITION DISEASE; PERIPHERAL BLOOD STEM CELL; PROTEIN BLOOD LEVEL; PROTEINURIA; TRANSTHORACIC ECHOCARDIOGRAPHY; TREATMENT RESPONSE; UREA NITROGEN BLOOD LEVEL;

ACUTE KIDNEY INJURY; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; MIDDLE AGED; PARAPROTEINEMIAS; TRANSPLANTATION, AUTOLOGOUS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84871564235     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CN107347     Document Type: Article

References (11)

1. Weichman K, Dember LM, Prokaeva T, Wright DG, Quillen K, Rosenzweig M, Skinner M, Seldin DC, Sanchorawala V. Clinical and molecular characteristics of patients with non-amyloid light chain deposition disorders, and outcome following treatment with high-dose melphalan and autologous stem cell transplantation. Bone Marrow Transplant. 2006; 38: 339-343.
2. Lin J, Markowitz GS, Valeri AM, Kambham N, Sherman WH, Appel GB, D'Agati VD. Renal monoclonal immunoglobulin deposition disease: the disease spectrum. J Am Soc Nephrol. 2001; 12: 1482-1492.
3. Pozzi C, D'Amico M, Fogazzi GB, Curioni S, Ferrario F, Pasquali S, Quattrocchio G, Rollino C, Segagni S, Locatelli F. Light chain deposition disease with renal involvement: clinical characteristics and prognostic factors. Am J Kidney Dis. 2003; 42: 1154-1163.
4. Royer B, Arnulf B, Martinez F, Roy L, Flageul B, Etienne I, Ronco P, Brouet J-C, Fermand J-P. High dose chemotherapy in light chain or light and heavy chain deposition disease. Kidney Int. 2004; 65: 642-648.
5. Nakamura M, Satoh M, Kowada S, Satoh H, Tashiro A, Sato F, Masuda T, Hiramori K. Reversible restrictive cardiomyopathy due to light-chain deposition disease. Mayo Clin Proc. 2002; 77: 193-196.
6. Fabbian F, Stabellini N, Sartori S, Tombesi P, Aleotti A, Bergami M, Uggeri S, Galdi A, Molino C, Catizone L. Light chain deposition disease presenting as paroxysmal atrial fibrillation: a case report. J Med Case Reports. 2007; 1: 187.
7. Firkin F, Hill PA, Dwyer K, Gock H. Reversal of dialysis-dependent renal failure in light-chain deposition disease by autologous peripheral blood stem cell transplantation. Am J Kidney Dis. 2004; 44: 551-555. PubMed
8. Kastritis E, Migkou M, Gavriatopoulou M, Zirogiannis P, Hadjikonstantinou V, Dimopoulos MA. Treatment of light chain deposition disease with bortezomib and dexamethasone. Haematologica. 2009; 94: 300-302.
9. Toor AA, Ramdane BA, Joseph J, Thomas M, O'Hara C, Barlogie B, Walker P, Joseph L. Cardiac nonamyloidotic immunoglobulin deposition disease. Mod Pathol. 2006; 19: 233-237.
10. Lorenz EC, Gertz MA, Fervenza FC, Dispenzieri A, Lacy MQ, Hayman SR, Gastineau DA, Leung N. Long-term outcome of autologous stem cell transplantation in light chain deposition disease. Nephrol Dial Transplant. 2008; 23: 2052-2057.
11. Petrakis I, Stylianou K, Mavroeidi V, Vardaki E, Stratigis S, Stratakis S, Xylouri I, Perakis C, Petraki C, Nakopoulou L, Daphnis E. Biopsy-proven resolution of renal light-chain deposition disease after autologous stem cell transplantation. Nephrol Dial Transplant. 2010; 25: 2020-2023.