Linezolid use in ventilator-associated pneumonia: Look at the body weight of your patient!

Minerva Anestesiologica

Volumn 78, Issue 12, 2012, Pages 1418-1419

  De Pascale, G ^a   Fortuna, S ^a   Navarra, P ^a   Antonelli, M ^a  

^a FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LINEZOLID; VANCOMYCIN;

AREA UNDER THE CURVE; BODY MASS; DISEASE ASSOCIATION; HUMAN; INTENSIVE CARE; LETTER; LIQUID CHROMATOGRAPHY; LUNG LAVAGE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MINIMUM INHIBITORY CONCENTRATION; OBESITY; VENTILATOR ASSOCIATED PNEUMONIA;

ACETAMIDES; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; BODY WEIGHT; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; OBESITY; OXAZOLIDINONES; PNEUMONIA, VENTILATOR-ASSOCIATED; STAPHYLOCOCCAL INFECTIONS;

EID: 84871494027     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (4)

1. Wunderink RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A et al. Linezolid in methicillin-resistant staphylococcus aureus nosocomial pneumonia: a randomized, controlled study. Clin Infect Dis 2012;54:621-9.
2. Pea F, Furlanut M, Cojutti P, Cristini F, Z amparini E, Franceschi L et al. Therapeutic drug monitoring of linezolid: a retrospective monocentric analysis. Antimicrob Agents Chemother 2010;54:4605-10.
3. Boselli E, Breilh D, Rimmelé T, Djabarouti S, Toutain J, Chassard D et al. Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia. Crit Care Med 2005;33:1529-3.
4. Dryden MS. Linezolid pharmacokinetics and pharmacodynamics in clinical treatment. J Antimicrob Chemother 2011;66:iv7-iv15.