Ion exchange chromatography

HPLC: Practical and Industrial Applications, Second Edition

Volumn , Issue , 2000, Pages 213-286

  Swadesh, Joel ^a  

^a Seraf Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; ION CHROMATOGRAPHY; PARTICLE SIZE;

COLUMN PACKINGS; HIGH PERFORMANCE APPLICATIONS; ION-EXCHANGE CHROMATOGRAPHY; REVERSED PHASE LIQUID-CHROMATOGRAPHY; SAMPLE SIZES;

ION EXCHANGE;

EID: 84871492646     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9781420042665     Document Type: Chapter

References (293)

1. Adams, B. A. and Holmes, E. L., Absorptive properties of synthetic resins. Part I., J. Soc. Chem. Ind. Trans. Comm., 54, 1, 1935.
2. Small, H., Ion Chromatography, Plenum Press, New York, 1989.
3. Horvath, C. G., Preiss, B. A., and Lipsky, S. R., Fast liquid chromatography: an investigation of operating parameters and the separation of nucleotides on pellicular ion exchangers, Anal Chem., 39, 1422, 1967.
4. Hamilton, P. B., Ion exchange chromatography of amino acids. A single column, high resolving, fully automatic procedure, Anal. Chem., 35, 2055, 1963.
5. Benson, Jr., J. V. and Patterson, J. A., Accelerated automatic chromatographic analysis of amino acids on a spherical resin, Anal. Chem., 37, 1108, 1965.
6. Kirkland, J. J., Techniques for high-performance liquid-liquid and ion exchange chromatography with controlled surface porosity column packings, J. Chromatogr. Sci., 7, 361, 1969.
7. Schmuckler, G., High-performance liquid ion-exchange chromatography, J. Liq. Chromatogr., 10, 1887, 1987.
8. Sellergren, B. and Shea, K. J., Chiral ion-exchange chromatography. Correlation between solute retention and a theoretical ion-exchange model using imprinted polymers, J. Chromatogr. A, 654, 17, 1993.
9. Fritz, J. S., Principles and applications of ion-exclusion chromatography, J. Chromatogr., 546, 111, 1991.
10. Yamamoto, A., Hayakawa, K., Matsunaga, A., Mizukami, E., and Miyazaki, M., Retention model of multiple eluent ion chromatography. A priori estimations of analyte capacity factor and peak intensity, J. Chromatogr., 627, 17, 1992.
11. Law, B. and Weir, S., Quantitative structure-retention relationships for secondary interactions in cation-exchange liquid chromatography, J. Chromatogr. A, 657, 17, 1993.
12. Jandera, P. and Churáček, J., Gradient elution in liquid chromatography. I. The influence of the composition of the mobile phase on the capacity ratio (retention volume, band width, and resolution) in isocratic elution — theoretical considerations, J. Chromatogr., 91, 207, 1974.
13. Gjerde, D. T., Schmuckler, G., and Fritz, J. S., Anion chromatography with low-conductivity eluents. II, J. Chromatogr., 187, 25, 1980.
14. Renn, C.N. and Synovec, R.E., Refractive index gradient detector of biopolymers separated by high-temperature liquid chromatography, J. Chromatogr., 536, 289, 1991.
15. Kissinger, P. T. and Radzik, D. M., Liquid chromatography/electrochemistry in pharmaceutical analysis, in HPLC in the Pharmaceutical Industry, Fong, G. W. and Lam, S. K., Eds., Marcel Dekker, New York, 1991, chap. 4.
16. Rocklin, R. D., Electrochemical detection, in A Practical Guide to HPLC Detection, Parriott, D., Ed., Academic Press, San Diego, 1993, chap. 6.
17. Wang, J., Electrochemical detection for liquid chromatography, in HPLC Detection: Newer Methods, Patonay, G., Ed., VCH Publishers, New York, 1992, chap. 5.
18. Walton, H. F. and Rocklin, R. D., Ion Exchange in Analytical Chemistry, CRC Press, Boca Raton, FL, 1990, chap. 4.
19. Kissinger, P. T., Biomedical applications of liquid chromatography-electrochemistry, J. Chromatogr., 488, 31, 1989.
20. Rothbart, H. L., Ion exchange separation processes, in An Introduction to Separation Science, Karger, B. L., Snyder, L. R., and Horváth, Cs., Eds., Wiley- Interscience, New York, 1973, chap. 12.
21. Strazhesko, D. N., Strelko, V. B., Belyakov, V. M., and Rubanik, S.C., Mechanism of cation exchange on silica gels, J. Chromatogr., 102, 191, 1974.
22. Chicz, R. M., Shi, Z., and Regnier, F. E., Preparation and evaluation of inorganic anion-exchange sorbents not based on silica, J. Chromatogr., 359, 121, 1986.
23. Huhn, G. and Müller, H., Polymer-coated cation exchangers in high-performance ion chromatography: preparation and application, J. Chromatogr., 640, 57, 1993.
24. Kutsuna, H., Ohtsu, Y., and Yamaguchi, M., Synthesis and characterization of highly stable polymer-coated aminosilica packing material for high-performance liquid chromatography, J. Chromatogr., 635, 187, 1993.
25. Small, H., Twenty years of ion chromatography, J. Chromatogr., 546, 3, 1991.
26. Arshady, R., Beaded polymer supports and gels. I. Manufacturing techniques, J. Chromatogr., 586, 181, 1991.
27. Kim, H.-B., Hayashi, M., Nakatani, K., Kitamura, N., Sasaki, K., Hotta, J.-I., and Masuhara, H., In situ measurements of ion exchange processes in single polymer particles: laser trapping microspectroscopy and confocal fluorescence microspectroscopy, Anal. Chem., 68, 409, 1996.
28. Wu, S.-L., Benedek, K., and Karger, B. L., Thermal behavior of proteins in high-performance hydrophobic-interaction chromatography, J. Chromatogr., 359, 3, 1986.
29. Velayudhan, A. and Horváth, Cs., On the stoichiometric model of electrostatic interaction chromatography for biopolymers, J. Chromatogr., 367, 160, 1986.
30. Rounds, M. A. and Regnier, F. E., Evaluation of a retention model for highperformance ion-exchange chromatography using two different displacing salts, J. Chromatogr., 283, 37, 1984.
31. Drager, R. R. and Regnier, F. E., Application of the stoichiometric displacement model of retention to anion-exchange chromatography of nucleic acids, J. Chromatogr., 359, 147, 1986.
32. Ståhlberg, J., Jönsson, B., and Horváth, Cs., Theory for electrostatic interaction chromatography of proteins, Anal. Chem., 63, 1867, 1991.
33. Manning, J., Limiting laws and counterion condensation in polyelectrolyte solutions I. Colligative properties, J. Chem. Phys., 51, 924, 1969.
34. Mazsaroff, I., Vàrady, L., Mouchawar, G. A., and Regnier, F. E., Thermodynamic model for electrostatic-interaction chromatography of proteins, J. Chromatogr., 499, 63, 1990.
35. Majors, R. E., New chromatography columns and accessories at the 1992 Pittsburgh conference, Part I, LC-GC, 10(3), 188, 1992.
36. Majors, R. E., New chromatography columns and accessories at the 1994 Pittsburgh conference, Part II, LC-GC, 12(4), 278, 1994.
37. Afeyan, N. B., Fulton, S. P., and Regnier, F. E., Perfusion chromatography packings for proteins and peptides, J. Chromatogr., 544, 267, 1991.
38. Yang, M.-H., Chang, K.-C., and Lin, J.-Y., Multifunctional ion-exchange stationary phases for high-performance liquid chromatography, J. Chromatogr. A, 722, 87, 1996.
39. Saari-Nordhaus, R. and Anderson, Jr., J. M., Ion chromatographic analysis of anions using a solid-phase chemical suppressor, Am. Lab., 26 (January), 28C, 1994.
40. Siriraks, A. and Stillian, J., Determination of anions and cations in concentrated bases and acids by ion chromatography, J. Chromatogr., 640, 151, 1993.
41. Jackson, P. E., Romano, J. P., and Wildman, B. J., Studies on system performance and sensitivity in ion chromatography, J. Chromatogr. A, 706, 3, 1995.
42. Pohl, C. A. and Johnson, E. L., Ion chromatography — the state of the art, J. Chromatogr. Sci., 18, 442, 1980.
43. Polite, L. N., McNair, H. M., and Rocklin, R. D., Linearity in ion chromatography, J. Liq. Chromatogr., 10, 829, 1987.
44. Sjögren A. and Dasgupta, P. K., Two-dimensional conductimetric detection in ion chromatography. Analyte identification, quantitation of very weak acid anions, and universal calibration, Anal. Chem., 67, 2110, 1995.
45. Gunasingham, H. and Fleet, B., Hydrodynamic voltammetry in continuousflow analysis, in Electroanalytical Chemistry: A Series of Advances, Vol. 16, Bard, A. J., Ed., Marcel Dekker, New York, 1989, 89.
46. Brunt, K., Electrochemical detectors for high-performance liquid chromatography and flow analysis systems, Trace Analysis, Vol. 1, Lawrence, J. F., Ed., Academic Press, New York, 1981, 47–120.
47. Rocklin, R. D., Detection in ion chromatography, J. Chromatogr., 546, 175, 1991.
48. Han, S. H., Lee, K. S., Cha, G. S., Liu, D., and Trojanowicz, M., Potentiometric detection in ion chromatography using multi-ionophore membrane electrodes, J. Chromatogr., 648, 283, 1993.
49. Trojánek, A. and De Jong, H. G., Fast scan A. C. voltammetry for better resolution of chromatographically overlapping peaks, Anal. Chim. Acta, 141, 115, 1982.
50. St. Claire, III, R. L. and Jorgenson, J. W., Characterization of an on-column electrochemical detector for open-tubular liquid chromatography, J. Chromatogr. Sci., 23, 186, 1985.
51. Kafil, J. B., Cheng, H.-Y., and Last, T. A., Quantitation of nucleic acids at the picogram level using high-performance liquid chromatography with electrochemical detection, Anal. Chem., 58, 285, 1986.
52. Bollet, C., Oliva, P., and Caude, M., Partial electrolysis electrochemical detector in high-performance liquid chromatography, J. Chromatogr., 149, 625, 1977.
53. Mayer, W. J. and Greenberg, M. S., Determination of some carbamate pesticides by high-performance liquid chromatography with electrochemical detection, J. Chromatogr., 208, 295, 1981.
54. Elrod Jr., L., Schmit, J. L., and Morley, J. A., Determination of isoproteronol sulfate on surfaces using high-performance liquid chromatography with electrochemical detection, J. Chromatogr. A, 723, 235, 1996.
55. Buchberger, W., Trends in the combination of high-performance liquid chromatography and electroanalytical methids, Chromatographia, 30, 577, 1990.
56. Krull, I. S., Ding, X.D., Selavka, C., and Nelson, R., Electrochemical detection in HPLC, LC Mag., 2(3), 214, 1984.
57. Johnson, D. C., Dobberpuhl, D., Roberts, R., and Vandeberg, P., Pulsed amperometric detection of carbohydrates, amines and sulfur species in ion chromatography — the current state of research, J. Chromatogr., 640, 79, 1993.
58. Weber, S. G., The dependence of current on flow rate in thin-layer electrochemical detectors used in liquid chromatography. A clarification, J. Electroanal. Chem., 145, 1, 1983.
59. Roe, D. K., Comparison of amperometric electrochemical detectors for HPLC through a figure of merit, Anal. Letts., 16, 613, 1983.
60. Kordorouba, V. and Pelletier, M., Ion chromatography using an electrochemical detector: response to non-electroactive anions, J. Liq. Chromatogr., 11, 2271, 1988.
61. Fenn, R. J., Siggia, S., and Curran, D. J., Liquid chromatography detector based on single and twin electrode thin-layer electrochemistry: application to the determination of catecholamines in blood plasma, Anal. Chem., 50, 1067, 1978.
62. Chen, Q., Wang, J., Rayson, G., Tian, B., and Lin, Y., Sensor array for carbohydrates and amino acids based on electrocatalytic modified electrodes, Anal. Chem., 65, 251, 1993.
63. Hoogvliet, J. C., Reijn, J. M., and van Bennekom, W. P., Multichannel amperometric detection system for liquid chromatography and flow inhection analysis, Anal. Chem., 63, 2418, 1991.
64. Thannhauser, T. W., McWherter, C. A., and Scheraga, H. A., Peptide mapping of bovine pancreatic ribonuclease A by reverse-phase high-performance liquid chromatography. II. A two-dimensional technique for determination of disulfide pairings using a continuous-flow disulfide detection system, Anal. Biochem., 149, 322, 1985.
65. Henderson, S. K. and Henderson, D. E., Enhanced UV detection on sugar phosphates by addition of a metal complex to the HPLC mobile phase, J. Chromatogr. Sci., 23, 222 (1985)
66. Yamauchi, S., Nakai, C., Nimura, N., Kinoshita, T., and Hanai, T., Highly sensitive detection of nonreducing carbohydrates by liquid chromatography, Analyst, 118, 769, 1993.
67. Yamauchi, S., Nakai, C., Nimura, N., Kinoshita, T., and Hanai, T., Development of a highly sensitive fluorescence reaction detection system for liquid chromatographic analysis of reducing carbohydrates, Analyst, 118, 773, 1993.
68. Blau, K. and Dodge, C.S., Continuous nephelometric monitoring of glycosaminoglycans eluted from chromatographic columns, Anal. Biochem., 58, 650, 1974.
69. Dollinger, G., Cunico, B., Kunitani, M., Johnson, D., and Jones, R., Practical on-line determination of biopolymer molecular weights by high-performance liquid chromatography with classical light-scattering detection, J. Chromatogr., 592, 215, 1992.
70. Hagel, L., Interferometric concentration determination of dextran after gel chromatography, Anal. Chem., 50, 569, 1978.
71. Petrie, L. M., Jakel, M. E., Brandvig, R. L., and Kroenig, J. G., Ion chromatography of sulfur dioxide, sulfate ion, and dithionate ion in aqueous mineral leachates, Anal. Chem., 65, 952, 1993.
72. Buchholz, A. E., Verplough, C. I., and Smith, J. L., A method for the simultaneous measurement of less than a part-per-million of chloride, nitrate, and sulfate in aqueous samples by nonsuppressed ion chromatography, J. Chromatogr. Sci., 20, 499, 1982.
73. Kadnar, R. and Rieder, J., Determination of anions in oilfield waters by ion chromatography, J. Chromatogr. A, 706, 301, 1995.
74. Kadnar, R. and Rieder, J., Determination of anions in amine solutions for sour gas treatment, J. Chromatogr. A, 706, 339, 1995
75. Hu, W. and Haraguchi, H., New approach for controlling the partitioning of analyte ions in ion chromatography witha water mobile phase, J. Chromatogr. A, 723, 251, 1996.
76. Rocklin, R. D., Pohl, C. A., and Schibler, J. A., Gradient elution in ion chromatography, J. Chromatogr., 411, 107, 1987.
77. Dabek-Zlotorzynska, E. and Dlouhy, J. F., Simultaneous determination of alkali, alkaline-earth metal cations and ammonium ion environmental samples by gradient ion chromatography, J. Chromatogr., 638, 35, 1993.
78. Klancke, J. W., Determination of monovalent and divalent cations and chloride in the carbacephalosporin loracarbef by ion chromatography, J. Chromatogr., 637, 63, 1993.
79. Smith, R. E., Yourtee, D., Bean, T., and McQuarrie, R. A., Ion chromatography on a new moderate capacity anion exchange column, J. Chromatogr. Sci., 31, 366, 1993.
80. Amey, M. D. H. and Bridle, D. H., Application and development of ion chromatography for the analysis of transition metal cations in the primary coolants of light water reactors, J. Chromatogr., 640, 323, 1993.
81. Jensen, D., Weiss, J., Rey, M. A., and Pohl, C. A., Novel weak acid cationexchange column, J. Chromatogr., 640, 65, 1993.
82. Nair, L. M., Saari-Nordhaus, R., and Anderson, Jr., J. M., Simultaneous separation of alkali and alkaline-earth cations on polybudaiene-maleic acid-coated stationary phase by mineral acid eluents, J. Chromatogr., 640, 41, 1993.
83. Lee, D. P., A new anion exchange phase for ion chromatography, J. Chromatogr. Sci., 22, 327, 1984.
84. Xianren, Q., Chong-yu, X., and Baeyens, W., Computer-assisted predictions of resolution, peak height and retention time for the separation of inorganic anions by ion chromatography, J. Chromatogr., 640, 3, 1993.
85. Benson, J. R. and Woo, D. J., Polymeric columns for liquid chromatography, J. Chromatogr. Sci., 22, 386, 1984.
86. Brenman, L. and Schmuckler, G., Quantitative determination of anions in fertilizers using ion chromatography, LC-GC, 11(4), 298, 1993.
87. Fujiwara, M., Matsushita, T., Kobayashi, T., Yamashoji, Y., and Tanaka, M., Preparation of an anion-exchange resin with quaternary phosphonium chloride and its adsorption behavior for noble metal ions, Anal. Chim. Acta, 274, 293, 1993.
88. Michigami, Y., Kuroda, Y., Ueda, K., and Yamamoto, Y., Determination of urinary fluoride by ion chromatography, Anal. Chim. Acta, 274, 299, 1993.
89. Cassidy, R. M. and Elchuk, S., Dynamic and fixed-site ion-exchange columns with conductimetric detection for the separation of inorganic ions, J. Chrom. Sci., 21, 454, 1983.
90. Cassidy, R. M. and Sun, L., Optimization of the anion-exchange separation of metal-oxalate complexes, J. Chromatogr. A, 654, 105, 1993.
91. Janoš, P., Separation of some metals as their anionic oxalate complexes by reversed-phase ion-interaction chromatography, J. Chromatogr., 635, 257, 1993.
92. Buldini, P. L., Sharma, J. L., and Mevoli, A., Determination of inorganic ions in carboxylic acids by ion chromatography, J. Chromatogr. A, 654, 123, 1993.
93. Buldini, P. L., Sharma, J. L., and Sharma, S., Ion-chromatographic determination of inorganic anions and cations in some reagents used in the electronics industry, J. Chromatogr. A, 654, 113, 1993.
94. Smith, R. E., Ion chromatography in the manufacture of multilayer circuit boards, J. Chromatogr., 546, 369, 1991.
95. Pereira, C. F., Application of ion chromatography to the determination of inorganic ions in foodstuffs, J. Chromatogr., 624, 457, 1992.
96. Frenzel, W., Schepers, D., and Schulze, G., Simultaneous ion chromatographic determination of anions and cations by series conductivity and flame photometric detection, Anal. Chim. Acta, 277, 103, 1993.
97. Krokhin, O. V., Smolenkov, A. D., Svintsova, N. V., Obrezkov, O. N., and Shpigun, O. A., Modified silica as a stationary phase for ion chromatography, J. Chromatogr. A, 706, 93, 1995.
98. Läubli, M. W. and Kampus, B., Cation analysis on a new poly(butadienemaleic acid)-based column, J. Chromatogr. A, 706, 99, 1995.
99. Bettmer, J., Cammann, K., and Robecke, M., Determination of organic ionic lead and mercury species with high-performance liquid chromatography using sulphur reagents, J. Chromatogr., 654, 177, 1993.
100. Janoš, P., Determination of stability constants of metal complexes from ion chromatographic measurements, J. Chromatogr., 641, 229, 1993.
101. Dasgupta, P. K., Ion chromatography: the state of the art, Anal. Chem., 64, 775A, 1992.
102. Marchetto, A., Mosello, R., Tartari, G. A., Muntau, H., Bianchi, M., Geiss, H., Serrini, G. and Lanza, G. S., Precision of ion chromatographic analyses compared with that of other analytical techniques through intercomparison exercises, J. Chromatogr. A, 706, 13, 1995.
103. Rowland, A. P., Woods, C., and Kennedy, V. H., Control of errors in anion chromatography applied to environmental research, J. Chromatogr. A, 706, 229, 1995.
104. Debowski, J. K. and Wilde, N. D., Determination of isocyanuric acid, ammeline, and melamine in crude isocyanuric acid by ion chromatography, J. Chromatogr., 639, 338, 1993.
105. Cox, G. B., Loscombe, C. R., Slucutt, M. J., Sugden, K., and Upfield, J. A., The preparation, properties and some applications of bonded ion-exchange packings based on microparticulate silica gel for high-performance liquid chromatography, J. Chromatogr., 117, 269, 1976.
106. Green, J. C. and Donaldson, R. M., The role played by ion chromatography in the assessment of amines for two-phase erosion corrosion control in nuclear electric’s steam-water circuits, J. Chromatogr., 640, 303, 1993.
107. Krol, J., Alden, P. G., Morawski, J., and Jackson, P. E., Ion chromatography of alkylamines and alkanolamines using conductivity detection, J. Chromatogr., 626, 165, 1992.
108. Perry, T. L. and Schroeder, W. A., The occurrence of amines in human urine: determination by combined ion exchange and paper chromatography, J. Chromatogr., 12, 358, 1963.
109. Tanaka, K., Ishizuka, T., and Sunahara, H., Chromatography of aliphatic amines on an anion-exchange resin, J. Chromatogr., 172, 484, 1979.
110. Dumont, P. J., Fritz, J. S., and Schmidt, L. W., Cation exchange chromatography in nonaqueous solvents, J. Chromatogr. A, 706, 109, 1995.
111. Adler, H., Margoshes, M., Snyder, L. R., and Spitzer, C., Rapid chromatographic method to determine polyamines in urine and whole blood, J. Chromatogr., 143, 125, 1977.
112. Villanueva, V. R. and Adlakha, R., Automated analysis of common basic amino acids, mono-, di-, and polyamine phenolic amines, and indoleamines in crude biological samples, Anal. Biochem., 91, 264, 1978.
113. Gehrke, C. W., Kuo, K. C., Ellis, R. L., and Waalkes, T.P., Polyamines — an improved automated ion-exchange method, J. Chromatogr., 143, 345, 1977.
114. Watanabe, S., Sato, S., Nagase, S., Tomita, M., Saito, T., and Ishizu, H., Automated quantitation of polyamines by improved cation-exchange high-performance liquid chromatography using a pump equipped with a plunger washing system, J. Liq. Chromatogr., 16, 619, 1993.
115. Moore, S. and Stein, W. H., Photometric ninhydrin method for use in the chromatography of amino acids, J. Biol. Chem., 176, 367, 1954.
116. Hirs, C. H. W., Stein, W. H., and Moore, S., The amino acid composition of ribonuclease, J. Biol. Chem., 211, 941, 1954.
117. Benedek, K. and Swadesh, J. K., HPLC of proteins and peptides in the pharmaceutical industry, in HPLC in the Pharmaceutical Industry, Vol. 47, Fong, G. W. and Lam, S. K., Eds., Marcel Dekker, New York, 1991, chap. 11.
118. Stone, K. L. and Williams, K. R., High-performance liquid chromatographic peptide mapping and amino acid analysis in the subnanomole range, J. Chromatogr., 359, 203, 1986.
119. Beecher, G. R., Design and assembly of an inexpensive, automated, microbore amino acid analyzer: separation and quantitation of amino acids in physiological fluids, Adv. Exp. Med. Biol., 105, 827, 1978.
120. Udenfriend, S., Stein, S., Böhlen, P., Dairman, W., Leimgruber, W., and Weigele, M., Fluorescamine: a reagent for assay of amino acids, peptides, proteins, and primary amines in the picomole range, Science, 178, 871, 1972.
121. Benson, J. R. and Hare, P. E., o-Phthalaldehyde: fluorogenic detection of primary amines in the picomole range: comparison with fluorescamine and ninhydrin, Proc. Natl. Acad. Sci. U.S.A., 72, 619, 1975.
122. Dong, M. W., Gant, J. R., and Benson, J. R., Characterization and performance of a high speed amino acid analysis column, Am. Biotech. Lab., 3, 34, 1985.
123. Hadžija, O. and Keglević, D., Simple method for the separation of amino acids, amino sugars, and amino alcohols related to the peptidoglycan components on a standard amino acid analyzer, J. Chromatogr., 138, 458, 1977.
124. Gorbics, L., Urge, L., Otvos-Papp, E., and Otvos, Jr., L., Determination of amino sugars in synthetic glycopeptides during the conditions of amino acid analysis utilizing precolumn derivatization and high-performance liquid chromatographic analysis, J. Chromatogr., 637, 43, 1993.
125. Yamada, H., Moriya, H., and Tsugita, A., Development of an acid hydrolysis method with high recoveries of tryptophan and cysteine for microquantities of protein, Anal. Biochem., 198, 1, 1991.
126. Hartkopf, J. and Erbersdobler, H. F., Stability of furosine during ion-exchange chromatography in comparison with reversed-phase high-performance liquid chromatography, J. Chromatogr., 635, 151, 1993.
127. Kedenburg, C.-P., A lithium buffer system for accelerated single-column amino acid analysis in physiological fluids, Anal. Biochem., 40, 35, 1971.
128. Murayama, K. and Shindo, N., Recommended method for the analysis of amino acids in biological materials, J. Chromatogr., 143, 137, 1977.
129. Ishimitsu, S., Fujimoto, S., and Ohara, A., Quantitative analysis of the isomers of hydroxyphenylalanine by ion-exchange chromatography, Chem. Pharm Bull., 24, 2556, 1976.
130. Houpert, Y., Tarallo, P., and Siest, G., Amino acid analysis by ion-exchange chromatography using a lithium elution gradient. Influence of methanol concentration and sample pH, J. Chromatogr., 115, 33, 1975.
131. Chin, C. C. Q., Ion-exchange chromatography of some amino acid derivatives found in proteins, Meth. Enzymol., 106, 17, 1984.
132. Atkin, G. E., and Ferdinand, W., Accelerated amino acid analysis: studies on the use of lithium citrate buffers and the effect of n-propanol, in the analysis of physiological fluids and protein hydrolyzates, Anal. Biochem., 38, 313, 1970.
133. Murren, C., Stelling, D., and Felstead, G., An improved buffer system for use in single-column gradient-elution ion-exchange chromatography of amino acids, J. Chromatogr., 115, 236, 1975.
134. Lou, M. F., A split stream ion exchange chromatographic method for isolating amino acids and peptides, Anal. Biochem., 55, 51, 1973.
135. Rahm, J., Analytical separation of amino acids on a cation-exchange resin cross-linked with m-divinylbenzene, J. Chromatogr., 115, 455, 1975.
136. Vandeberg, P. J. and Johnson, D. C., Pulsed electrochemical detection of cysteine, cystine, methionine, and glutathione at gold electrodes following their separation by liquid chromatography, Anal. Chem., 65, 2713, 1993.
137. Fung, Y.-S. and Mo, S.-Y., Determination of amino acids and proteins by dualelectrode detection in a flow system, Anal. Chem., 67, 1121, 1995.
138. Skelly, N. E., Gradient elution in the separation of chlorophenols by ion exchange, Anal. Chem., 33, 271, 1961.
139. Small, H., Stevens, T. S., and Bauman, W. C., Novel ion exchange chromatographic method using conductimetric detection, Anal. Chem., 47, 1801, 1975.
140. Mayer, W. J. and Greenberg, M. S., A comparison of differential pulse and D. C. amperometric detection modes for the liquid chromatographic determination of oxalic acid, J. Chromatogr. Sci., 17, 614, 1979.
141. Kasai, Y., Tanimura, T., Tamura, Z., Tanimura, T., and Ozawa, Y., Automated determination of carboxylic acids by anion-exchange chromatography with specific color reaction, Anal. Chem., 49, 655, 1977.
142. Goudie, A. J., and Rieman, W., Chromatographic separation and determination of fruit acids, Anal. Chim. Acta, 26, 419, 1962.
143. Hirayama, N., Maruo, M., and Kuwamoto, T., Determination of dissociation constants of aromatic carboxylic acids by ion chromatography, J. Chromatogr., 639, 333, 1993.
144. Leubolt, R. and Klein, H., Determination of sulphite and ascorbic acid by high-performance liquid chromatography withe electrochemical detection, J. Chromatogr., 640, 271, 1993.
145. Chiu, G., Analysis of mixtures of cyanovaleric and other carboxylic acids by liquid chromatography, J. HRC&CC, 9, 57, 1986.
146. Chiu, G., Separation of carboxylic acids by temperature programmed liquid chromatography, J. HRC&CC, 9, 410, 1986.
147. Grosjean, D. J., Van Neste, A., and Parmar, S. S., Analysis of atmospheric carboxylic acids using single column ion exclusion chromatography with ultraviolet detection, J. Liq. Chromatogr., 12, 3007, 1989.
148. Stinson, E. A., Subers, M. H., Petty, J., and White, Jr., J. W., The composition of honey. V. Separation and identification of the organic acids, Arch. Biochem. Biophys., 89, 6, 1960.
149. Jahangir, L. M. and Samuelson, O., Cation-exchange resins and non-ionic cross-linked polymers in analysis of aqueous solutions for organic contaminants, Anal. Chim. Acta, 100, 53, 1978.
150. Lange, H.W. and Hempel, K., Automated chromatography of aromatic acids, aldehydes, and alcohols with an amino acid analyzer, J. Chromatogr., 59, 53, 1971.
151. Peldszus, S., Huck, P. M., and Andrews, S. A., Determination of short-chain aliphatic, oxo- and hydroxy acids in drinking water at low microgram per liter concentrations, J. Chromatogr. A, 723, 27, 1996.
152. Lee, H. K. and Hoffman, N. E., Effect of temperature on the retention of simple organic compounds in ion-exchange HPLC, J. Chromatogr. Sci., 32, 97, 1994.
153. Feibush, B. and Santasania, C. T., Hydrophilic shielding of hydrophobic, cation- and anion-exchange phases for separation of small analytes: direct injection of biological fluids onto high performance chromatographic columns, J. Chromatogr., 544, 41, 1991.
154. Vreeken, R. J., Ghijsen, R. T., Frei, R. W., de Jong, G. J., and Brinkman, U. A. Th., Coupling of ion-pair liquid chromatography and thermospray mass spectrometry via phase-system switching with a polymeric trapping column, J. Chromatogr. A, 654, 65, 1993.
155. Freifelder, D., Molecular Biology, 2nd ed., Jones and Bartlett, Boston, 1987, 60–64.
156. Floyd, T. R., Yu, L. W., and Hartwick, R. A., Use of diluted anion-exchange and hydrophobic properties in separating single-stranded oligodeoxyribonucleotides on mixed-ligand stationary phases, Chromatographia, 21, 402, 1986.
157. Floyd, T. R., Cicero, S.E., Fazio, S. D., Raglione, T. V., Hsu, S.-H., Winkle, S. A., and Hartwick, R. A., Mixed-mode hydrophobic ion exchange for the separation of oligonucleotides and DNA fragments using HPLC, Anal. Biochem., 154, 570, 1986.
158. Basiuk, V. A. and Chuko, A. A., Selectivity of bonded stationary phases containing uracil derivatives for liquid chromatography of nucleic acid components, J. Chromatogr. Sci., 31, 120, 1993.
159. Cohn, W. E., The anion-exchange separation of ribonucleotides, J. Am. Chem. Soc., 72, 1471, 1950.
160. Wade, H. E., The fractionation of phosphate esters on ion-exchange resin by a new system of pH-gradient elution, Biochem. J., 77, 534, 1960.
161. Pal, B. C., Novel application of a sugar-borate complexation for separation of ribo-, 2 ′ -deoxyribo-, and arabinonucleosides on cation exchange resin, J. Chromatogr., 148, 545, 1978.
162. Bates, M. and Avdalović, N., The value of Dowex ® -50 in fractionation of nucleotides from acid-soluble pool. A caution, Anal. Biochem., 61, 508, 1974.
163. Breter, H.-J., Seibert, G., and Zahn, R. K., Single-step separation of major and rare ribonucleosides and deoxyribonucleosides by high-performance liquid cation-exchange chromatography for the determination of the purity of nucleic acid preparations, J. Chromatogr., 140, 251, 1977.
164. Floridi, A., Palmerini, C. A., and Fini, C., Simultaneous analysis of bases, nucleosides, and nucleoside mono- and polyphosphates by high-performance liquid chromatography, J. Chromatogr., 138, 203, 1977.
165. Alonso, J., Nogues, M. V., and Cuchillo, C. M. Separation of RNA derivatives by high-performance anion-exchange liquid chromatography, J. Liq. Chromatogr., 8, 299, 1985.
166. Alpert, A. J. and Regnier, F. E., Preparation of a porous microparticulate anionexchange chromatography support for proteins, J. Chromatogr., 185, 375, 1979.
167. Frenkel, K. and Klein, C. B., Methods used for analyses of “environmentally” damaged nucleic acids, J. Chromatogr., 618, 289, 1993.
168. Köster, H. and Frank, R., Automated chromatography of protected oligonucleotides with high separation efficiency, Chromatographia, 9, 497, 1976.
169. 3+. II. Effect of the physical state of DNA on chromatographic profiles, J. Chromatogr., 53, 580, 1970.
170. +. IV. Effect of protein association on the chromatographic profiles of DNA, J. Chromatogr., 56, 151, 1971.
171. Kothari, R.M., Some aspects of fractionation of DNA on an IR-120 Al 3+. VI. The effect of pH and temperature variation on the chromatographic profiles of DNA, J. Chromatogr., 59, 194, 1971.
172. Shankar, V. and Joshi, P. N., Fractionation of RNA on a metal ion equilibrated cation exchanger. I. Chromatographic profiles of RNA on an Amberlite ® IR- 120 (Al +3) column, J. Chromatogr., 90, 99, 1974.
173. Wulfson, A. N. and Yakimov, S. A., HPLC of nucleotides. II. General methods and their development for analysis and preparative separation: an approach to selectivity control, J. HRC&CC, 7, 442, 1984.
174. Singhal, R. P., Griffin, G. D., and Novelli, G. D., Separation of transfer ribonucleic acids on polystyrene anion exchangers, Biochemistry, 23, 5083, 1976.
175. Müller, W., Fractionation of DNA restriction fragments with ion-exchangers for high-performance liquid chromatography, Eur. J. Biochem., 155, 203, 1986.
176. Ozaki, H., Wada, H., Takeuchi, T., Makino, K., Fukui, T., and Kato, Y., Behaviour of single-stranded oligodeoxyribonucleotides on a DEAE-5PW anionexchange column, J. Chromatogr., 322, 243, 1985.
177. McLaughlin, L. W. and Bischoff, R., Resolution of RNA using high-performance liquid chromatography, J. Chromatogr., 418, 51, 1987.
178. Colpan, M. and Riesner, D., High-performance liquid chromatography of high-molecular-weight nucleic acids on the macroporous ion exchanger, Nucleogen ®, J. Chromatogr., 296, 339, 1984.
179. Coppella, S. J., Acheson, C. M., and Dhurjati, P., Isolation of high-molecularweight nucleic acids for copy number analysis using high-performance liquid chromatography, J. Chromatogr., 402, 189, 1987.
180. Drager, R. R. and Regnier, F. E., High-performance anion-exchange chromatography of oligonucleotides, Anal. Biochem., 145, 47, 1985.
181. Garon, C. F. and Peterson, L. L., An improved method for the isolation of supercoiled DNA molecules using ion-exchange column chromatography, Gene Anal. Technol., 4, 5, 1987.
182. Sawai, H., Analysis and purification of synthetic large oligodeoxyribonucleotides by HPLC on RPC-5 like resin, Nucleic Acids Res., 17, 113, 1986.
183. Baba, Y., Prediction of the behavior of oligonucleotides in high-performance liquid chromatography and capillary electrophoresis, J. Chromatogr., 618, 41, 1993.
184. Baba, Y., Fukuda, M., and Yoza, N., Computer-assisted retention prediction system for oligonucleotides in gradient anion-exchange chromatography, J. Chromatogr., 458, 385, 1988.
185. Bourque, A. J. and Cohen, A. S., Quantitative analysis of phosphorothioate oligonucleotides in biological fluids using fast anion-exchange chromatography, J. Chromatogr., 617, 43, 1993.
186. Murray, Jr., E. D. and Clarke, S., Synthetic peptide substrates for the erythrocyte protein carboxyl methyltransferase, J. Biol. Chem., 259, 10722, 1984.
187. Bonnerjea, J., Oh, S., Hoare, M., and Dunnill, P., Protein purification: the right step at the right time, BioTechnology, 4, 954, 1986.
188. Siezen, R. J., Kaplan, E. D., and Anello, R. D., Superior resolution of γ -crystallins from microdissected eye lens by cation-exchange high-performance liquid chromatography, Biochem. Biophys. Res. Comm., 127, 153, 1985.
189. Hatch, R. G., Very-high-speed anion-exchange chromatography of proteins using monodisperse nonporous polymer particles, J. Chromatogr. Sci., 31, 469 1993.
190. Mikeš, O., Š trop, P., Hostomská, Z., Smrž, M., Slováková, S., andČ oupek, J., Ion-exchange derivatives of Spheron. V. Sulphate and sulpho derivatives, J. Chromatogr., 301, 93, 1984.
191. Atassi, M. Z., Perlstein, M. T., Rosenblatt, M. C., and Rocek, P., Fully automated simple analytical peptide chromatography on the amino acid analyzer at the 10 –8 mole level, Anal. Biochem., 49, 164, 1972.
192. Hartley, R. W., Peptide analysis and preparation with an amino acid analyzer, Anal. Biochem., 46, 676, 1972.
193. Dizdaroglu, M., Krutzsch, H. C., and Simic, M. G., Separation of angiotensins by high-performance liquid chromatography on a weak anion-exchange bonded phase, Anal. Biochem., 123, 190, 1982.
194. Crimmins, D. L., Gorka, J., Thoma, R. S., and Schwartz, B. D., Peptide characterization with a sulfoethyl aspartamide column, J. Chromatogr., 443, 63, 1988.
195. Bennett, H. P. J., Use of ion-exchange Sep-Pak ® cartridges in the batch fractionation of pituitary peptides, J. Chromatogr., 359, 383, 1986.
196. Weber, S. G., Tsai, H., and Sandberg, M., Electrochemical detection of dipeptides with selectivity against amino acids, J. Chromatogr., 638, 1, 1993.
197. Takahashi, N., Takahashi, Y., Ishioka, N., Blumberg, B., and Putnam, F. W., Application of an automated tandem high-performance liquid chromatographic system to peptide mapping of genetic variants of human serum albumin, J. Chromatogr., 359, 181, 1986.
198. Randall, C. S., Malefyt, T. R., and Sternson, L. A., Approaches in the analysis of peptides, in Peptide and Protein Drug Delivery, Lee, V. H. L., Ed., Marcel Dekker, New York, 1991, chap. 5.
199. Vanacek, G. and Regnier, F. E., Macroporous high-performance anion-exchange supports for proteins, Anal. Biochem., 121, 156, 1982.
200. Kato, Y., Nakamura, K., and Hashimoto, T., New high-performance cation exchanger for the separation of proteins, J. Chromatogr., 294, 207, 1984.
201. Weinbrenner, W. F. and Etzel, M. R., Competitive adsorption of α -lactalbumin and bovine serum albumin to a sulfopropyl ion-exchange membrane, J. Chromatogr. A, 662, 414, 1994.
202. Kato, Y., Nakamura, K., Yamazaki, Y., and Hashimoto, T., Comparison of highperformance ion-exchange chromatography and gel electrophoresis in protein separations, J. Chromatogr., 318, 358, 1985.
203. Boulias, C., Pang, H., Mastronardi, F., and Moscarello, M. A., The isolation and characterization of four myelin basic proteins from the unbound fraction during CM52 chromatography, Arch. Biochem. Biophys., 322, 174, 1995.
204. Huisman, T. H. J. and Dozy, A. M., Studies on the heterogeneity of hemoglobin. IV. Chromatographic behavior of different human hemoglobins on anionexchange cellulose (DEAE-cellulose), J. Chromatogr., 7, 180, 1962.
205. Gooding, K. M., Lu, K.-C., and Regnier, F. E., High-performance liquid chromatography of hemoglobins. I. Determination of hemoglobin A 2, J. Chromatogr., 164, 506, 1979.
206. Alpert, A. J., Cation-exchange high-performance liquid chromatography of proteins on poly(aspartic acid)-silica, J. Chromatogr., 266, 23, 1983.
207. Burke, D. J., Duncan, J. K., Siebert, C., and Ott, G. S., Rapid cation-exchange chromatography of hemoglobins and other proteins, J. Chromatogr., 359, 533, 1986.
208. Narum, D. L., Welling, G. W., and Thomas, A. W., Ion-exchange-immunoaffinity purification of a recombinant baculovirus Plasmodium falciparum apical membrane antigen, PF83/AMA-1, J. Chromatogr. A, 657, 357, 1993.
209. Yang, Y.-B., Harrison, K., and Kindsvater, J., Characterization of a novel stationary phase derived from a hydrophilic polystyrene-based resin for protein cation-exchange high-performance liquid chromatography, J. Chromatogr. A, 723, 1, 1996.
210. Kaltenbrunner, O., Tauer, C., Brunner, J., and Jungbauer, A., Isoprotein analysis by ion-exchange chromatography using a linear pH gradient combined with a salt gradient, J. Chromatogr., 639, 41, 1993.
211. Greve, K. F., Hughes, D. E., Richberg, P., Kats, M., and Karger, B. L., Liquid chromatographic and capillary electrophoretic examination of intact and degraded fusion protein CTLA4Ig and kinetics of conformational transition, J. Chromatogr. A, 723, 273, 1996.
212. Mhatre, R., Nashabeh, W., Schmalzing, D., Yao, X., Fuchs, M., Whitney, D., and Regnier, F., Purification of antibody Fab fragments by cation-exchange chromatography and pH gradient elution, J. Chromatogr. A, 707, 225, 1995.
213. Josić, Dj., Hofmann, W., Wieland, B., Nuck, R., and Reutter, W., Anion-exchange high-performance liquid chromatography of membrane proteins from liver and Morris hepatomas, J. Chromatogr., 359, 315, 1986.
214. Imaoka, S. and Funae, Y., Ion-exchange high-performance liquid chromatography of membrane-bound protein cytochrome P-450, J. Chromatogr., 375, 83, 1986.
215. Cacia, J., Quan, C. P., Vasser, M., Sliwkowski, M. B., and Frenz, J., Protein sorting by high-performance liquid chromatography I. Biomimetic interaction chromatography of recombinant human deoxyribonuclease I on polyionic stationary phases, J. Chromatogr., 634, 229, 1993.
216. Kopaciewicz, W. and Regnier, F. E., Mobile phase selection for the high-performance ion-exchange chromatography of proteins, Anal. Biochem., 133, 251, 1983.
217. Roush, D. J., Gill, D. S., and Willson, R. C., Anion-exchange chromatographic behavior of recombinant rat cytochrome b 5. Thermodynamic driving forces and temperature dependence of the stoichiometric displacement parameter Z, J. Chromatogr., 653, 207, 1993.
218. Jungbauer, A., Uhl, K., Schulz, P., Tauer, C., Gruber, G., Steindl, F., Buchacher, A., Schoenhofer, W., and Unterluggauer, F., Displacement effects in large-scale chromatography?, Biotechnol. Bioeng., 39, 579, 1992.
219. Herzig, C. M., Schoeppe, W., and Scherberich, J., Angiotensinase A (aminopeptidase A): properties of chromatographically purified isoforms from human kidney, J. Chromatogr., 625, 73, 1992.
220. Richey, J. S., Optimal pH conditions for ion exchangers on macroporous supports, Meth. Enzymol., 104, 223, 1984.
221. Mazsaroff, I., Bischoff, R., Tice, P. A., and Regnier, F. E., Influence of mobile phase pH on high-performance liquid chromatographic column loading capacity, J. Chromatogr., 437, 429, 1988.
222. Malmquist, G. and Lundell, N., Characterization of the influence of displacing salts on retention in gradient-elution ion-exchange chromatography of peptides and proteins, J. Chromatogr., 627, 107, 1992.
223. Peelen, G. O. H., de Jong, J. G. N., and Wevers, R. A., High-performance liquid chromatography of monosaccharides and oligosaccharides in a complex biological matrix, Anal. Biochem., 198, 334, 1991.
224. Hotchkiss, Jr., A. T., Hicks, K. B., Doner, L. W., and Irwin, P. L., Isolation of oligogalacturonic acids in gram quantities by preparative H.P.L.C., Carb. Res., 215, 81, 1991.
225. Yamauchi, S., Nimura, N., and Kinoshita, T., Protamine-coated silica gel as packing material for high performance liquid chromatography of carbohydrates, Analyst, 118, 161, 1993.
226. Kragten, E. A., Kamerling, J. P., and Vliegenthart, J. F. G., Composition analysis of carboxymethlcellulose by high-pH anion-exchange chromatography with pulsed amperometric detection, J. Chromatogr., 623, 49, 1992.
227. De Ruiter, G. A., Schols, H. A., Voragen, A. G. J., and Rombouts, F. M., Carbohydrate analysis of water-soluble uronic acid-containing polysaccharides with high-performance anion-exchange chromatography using methanolysis combined with TFA hydrolysis is superior to four other methods, Anal. Biochem., 207, 176, 1992.
228. Martens, D.A. and Frankenberger, Jr., W. T., Determination of glycuronic acids by high-performance anion chromatography with pulsed amperometric detection, Chromatographia, 30, 651, 1990.
229. Martens, D.A. and Frankenberger, Jr., W. T., Determination of saccharides by high-performance anion-exchange chromatography with pulsed amperometric detection, Chromatographia, 29, 7, 1990.
230. Reddy, G. P., Hayat, U., Abeygunawardana, C., Fox, C, Wright, A. C., Maneval, D., Bush, C. A., and Morris, Jr., J. G., Purification and determination of the structure of capsular polysaccharide of Vibrio vulnificus M06-24, J. Bacteriol., 174, 2620, 1992.
231. Paskach, T. J., Lieker, H.-P., Reilly, P. J., and Thielecke, K., High-performance anion-exchange chromatography of sugars and sugar alcohols on quaternary ammonium resins under alkaline conditions, Carb. Res., 215, 1, 1991.
232. Kynaston, J. A., Fleming, S. C., Laker, M. F. and Pearson, A. D. J., Simultaneous quantification of mannitol, 3-O-methyl glucose and lactulose in urine by HPLC with pulsed electrochemical detection, for use in studies of intestinal permeability, Clin. Chem., 39, 453, 1993.
233. Pastore, P., Lavagnini, I., and Versini, G., Ion chromatographic determination of monosaccharides from trace amounts of glycosides isolated from grape musts, J. Chromatogr., 634, 47, 1993.
234. van Riel, J. and Olieman, C., Selectivity control in the anion-exchange chromatographic determination of saccharides in dairy products using pulsed amperometric detection, Carb Res., 215, 39, 1991.
235. Tabata, S. and Dohi, Y., An assay for oligo-(1 → 4) → (1 → 4)-glucantransferase activity in the glycogen debranching enzyme system by using HPLC with a pulsed amperometric detector, Carb. Res., 230,179, 1992.
236. LaCourse, W. R. and Johnson, D. C., Optimization of waveforms for pulsed amperometric detection (P.A.D.) of carbohydrates following separation by liquid chromatography, Carb. Res., 215, 159, 1991.
237. Palu, M. and Samuelson, O., Influence of aromatic compounds in sugar chromatography on anion-exchange resins, Talanta, 24, 264, 1977.
238. Tomiya, N., Suzuki, T., Awaya, J., Mizuno, K., Matsubara, A., Nakano, K., and Kurono, M., Determination of monosaccharides and sugar alcohols in tissues from diabetic rats by high-performance liquid chromatography with pulsed amperometric detection, Anal. Biochem., 206, 98, 1992.
239. Togami, D. W., Poulsen, B. J., Batalao, C. W., and Rolls, W. A., Separation of carbohydrates and carbohydrate derivatives by HPLC with cation-exchange columns at high pH, BioTechniques, 10, 650, 1991.
240. Scobell, H. D. and Brobst, K. M., Rapid high-resolution separation of oligosaccharides on silver form cation-exchange resins, J. Chromatogr., 212, 51, 1981.
241. Blanken, W. M., Bergh, M. L. E., Koppen, P. L., and van den Eijnden, D.H., High-pressure liquid chromatography of neutral oligosaccharides: effects of structural parameters, Anal. Biochem., 145, 322, 1985.
242. Kunitani, M. and Kresin, L., High-performance liquid chromatographic analysis of carbohydrate mass composition in glycoproteins, J. Chromatogr., 632, 19 1993.
243. Lampio, A. and Finne, J., Sugar analysis of glycoproteins and glycolipids after methanolysis by high-performance liquid chromatography with pulsed amperometric detection, Anal. Biochem., 197, 132, 1991.
244. Stefansson, M. and Westerlund, D., Ion-pair LC of carbohydrates at alkaline pH. Separation and retention behavior of glycoconjugates, Chromatographia, 35, 55, 1993.
245. Ogawa, H. K., Takeuchi, Y., Uchibori, H., Matsumoto, I., and Seno, N., Determination of N-acetylneuraminic acid and N-glycolylneuraminic acid in glycoproteins by high-performance liquid chromatography without derivatization, J. Chromatogr., 612, 145, 1993.
246. Mrochek, J. E., Dinsmore, S. R., Tormey, D. C., and Waalkes, T. P., Proteinbound carbohydrates in breast cancer, liquid-chromatographic analysis for mannose, galactose, fucose, and sialic acid in serum, Clin. Chem., 22, 1516, 1976.
247. Ishihara, K., Kameyama, J. -I., and Hotta, K., Development of an HPLC method to estimate hexosamines and its application to determine mucin content in rat and human gastric mucosa, Comp. Biochem. Physiol., 104B, 781, 1993.
248. Hicks, K. B., Advances in Carbohydrate Chemistry and Biochemistry, Vol. 46, Tipson, R. S. and Horton, D., Eds., Academic Press, New York, 1988, 17.
249. Ammeraal, R. N., Delgado, G. A. Tenbarge, F. L., and Friedman, R. B., Highperformance anion-exchange chromatography with pulsed amperometric detection of linear and branched glucose oligosaccharides, Carb. Res., 215, 179, 1991.
250. van der Hoeven, R. A. M., Niessen, W. M. A., Schols, H. A., Bruggink, C., Voragen, A. G. J., and van der Greef, J., Characterization of sugar oligomers by on-line high-performance anion-exchange chromatography-thermospray mass spectrometry, J. Chromatogr., 627, 63, 1992.
251. Townsend, R. R., Atkinson, P. H., and Trimble, R. B., Separation of high-mannose isomers from yeast and mammalian sources using high pH anion-exchange chromatography, Carb. Res., 215, 211. 1991.
252. Hardy, M. R. and Townsend, R. R., Separation of positional isomers of oligosaccharides and glycopeptides by high-performance anion-exchange chromatography with pulsed amperometric detection, Proc. Natl. Acad. Sci. U.S.A., 85, 3289, 1988.
253. Kamerling, J. P., Gruter, M., Hoffman, R. A., Kragten, E. A., and Vliegenthart, J. F. G., A useful fractionation method in the characterization of bacterial exopolysaccharides, arabinoxylans, and substituted celluloses, Carb. Neth ., 9, 27, 1993.
254. Niessen, W. M. A., van der Hoeven, R. A. M., van der Greef, J., Schols, H. A, Voragen, A. G. J., and Bruggink, C., Recent progress in high-performance anion-exchange chromatography-thermospray mass spectrometry of oligosaccharides, J. Chromatogr., 647, 319, 1993.
255. Holmbeck, S. and Lerner, L., Separation of hyaluronan oligosaccharides by the use of anion-exchange HPLC, Carb. Res., 239, 239, 1993.
256. Watson, E., Bhide, A., Kenney, W. C., and Lin, F.-K., High-performance anionexchange chromatography of asparagine-linked oligosaccharides, Anal. Biochem., 205, 90, 1992.
257. Reddy, G. P. and Bush, C. A., High-performance anion exchange chromatography of neutral milk oligosaccharides and oligosaccharide alditols derived from mucin glycoprotein, Anal. Biochem., 198, 278, 1991.
258. Hernandez, L. M., Ballou, L., and Ballou, C. E., Separation of yeast asparaginelinked oligosaccharides by high-performance anion-exchange chromatography, Carb. Res., 203, 1, 1990.
259. Linhardt, R. J., Gu, K. N, Loganathan, D., and Carter, S. R., Analysis of glycosaminoglycan- derived oligosaccharides using reversed-phase ion-pairing and ion-exchange chromatography with suppressed conductivity detection, Anal. Biochem., 181, 288, 1989.
260. Somlyo, B., Kovats, E., Keler, T., and Nowotny, A., Column liquid chromatography of endotoxins, J. Chromatogr., 525, 329, 1990.
261. Thurl, S., Offermanns, J., Müller-Werner, B., and Sawatzki, G., Determination of neutral oligosaccharide fractions from human milk by gel permeation chromatography, J. Chromatogr., 568, 291, 1991.
262. Ohta, M., Matsuura, F., Kobayashi, Y., Shigeta, S., Ono, K., and Oka, S., Further characterization of allergenically active oligosaccharitols isolated from a sea squirt H-antigen, Arch. Biochem. Biophys., 290, 474, 1991.
263. Heyraud, A. and Leonard, C., Analysis of oligouronates on reversed-phase ion-pair H.P.L.C.: role of the mobile phase, Carb. Res., 215, 105, 1991.
264. Koizumi, K., Okada, Y., and Fukuda, M., High-performance liquid chromatography of mono- and oligo-saccharides on a graphitized carbon column, Carb. Res., 215, 67, 1991.
265. Suzuki-Sawada, J., Umeda, Y., Kondo, A., and Kato, I., Analysis of oligosaccharides by on-line high-performance liquid chromatography and ion-spray spectrometry, Anal. Biochem., 207, 203, 1992.
266. Soga, T., Inoue, Y., and Yamaguchi, K., Determination of carbohydrates by hydrophilic interaction chromatography with pulsed amperometric detection using postcolumn pH adjustment, J. Chromatogr., 625, 151, 1992.
267. Green, E. D. and Baenziger, J. U., Separation of anionic oligosaccharides by high-performance liquid chromatography, Anal. Biochem., 158, 42, 1986.
268. Hotchkiss, Jr., A. T., Haines, R. M., and Hicks, K. B., Improved gram-quantity isolation of malto-oligosaccharides by preparative HPLC, Carb. Res., 242, 1, 1993.
269. Feste, A. S. and Khan, I., Separation of glucooligosaccharides and polysaccharide hydrolysates by gradient elution electrophilic interaction chromatography with pulsed amperometric detection, J. Chromatogr., 630,129, 1993.
270. Takahashi, N., Wada, Y., Awaya, J., Kurono, M., and Tomiya, N., Two-dimensional elution map of GalNAc-containing N-linked oligosaccharides, Anal. Biochem., 208, 96, 1993.
271. Femia, R. E. and Weinberger, R., Determination of reducing and non-reducing carbohydrates in food products by liquid chromatography with post-column catalytic hydrolysis and derivatization: comparison with refractive index detection, J. Chromatogr., 402, 127, 1987.
272. Christ, W., Arndt, G., and Schulze, G., Separation behavior of nicotinamide and thionicotinamide derivatives on Dowex® 1-X8, J. Chromatogr., 106, 418, 1975.
273. Illingworth, D. R. and Portman, O. W., An improved method for separating the products of lecithin and lysolecithin catabolism, J. Chromatogr., 73, 262, 1972.
274. Rindi, G. and De Giuseppe, L., A new chromatographic method for the determination of thiamine and its mono-, di-, and tri-phosphates in animal, Biochem. J., 78, 602, 1961.
275. Fahey, R. C., Newton, G. L., Dorian, R., and Kosower, E. M., Analysis of biological thiols: quantitative determination of thiols at the picomole level based upon derivatization with monobromobimanes and separation by cation-exchange chromatography, Anal. Biochem., 111, 357, 1981.
276. Callmer, K. and Davies, L., Separation and determination of vitamin B1, B2, B6, and nicotinamide in commercial vitamin preparations using high-performance cation-exchange chromatography, Chromatographia, 7, 644, 1974.
277. Virtanen, V. and Lajunen, L. H. J., High-performance liquid chromatographic method for simultaneous determination of clodronate and some clodronate esters, J. Chromatogr., 617, 291, 1993.
278. Shamsi, S. A. and Danielson, N. D., Ion chromatography of polyphosphates and polycarboxylates using a naphthalenetrisulfonate eluent with indirect photometric and conductivity detection, J. Chromatogr. A, 653, 153, 1993.
279. Yokoyama, Y., Kondo, M. and Sato, H., Determination of alkylbenzenesulphonates in environmental water by anion-exchange chromatography, J. Chromatogr., 643, 169, 1993.
280. Pan, N. and Pietrzyk, D. J. Separation of anionic surfactants on anion exchangers, J. Chromatogr., 706, 327, 1995
281. Klein, H. and Leubolt, R., Ion-exchange high-performance liquid chromatography in the brewing industry, J. Chromatogr., 640, 259, 1993.
282. Massardier, V. and Vialle, J., Investigation of liquid chromatographic systems for the separation of sulphonium salts, Anal. Chim. Acta, 281, 391, 1993.
283. Rounds, M.A. and Nielsen, S. S., Anion-exchange high-performance liquid chromatography with post-column detection for the analysis of phytic acid and other inositol phosphates, J. Chromatogr. A, 653, 148, 1993.
284. Jones, N. R. and Burt, J. R., The separation and determination of sugar phosphates, with particular reference to extracts of fish tissue, Analyst, 85, 810, 1960.
285. Rotman, B., Uses of ion exchange resins in microbiology, Bacteriol. Rev., 24, 251, 1960.
286. Budzynski, A. Z., Olexa, S. A., and Sawyer, R. T., Composition of salivary gland extracts from the leech Haementeria ghilianii, Proc. Soc. Exp. Biol. Med., 168, 259, 1981.
287. Budzynski, A. Z., Olexa, S. A., Brizuela, B. S., Sawyer, R. T., and Stent, G. S., Anticoagulant and fibrinolytic properties of salivary proteins from the leech Haementeria ghilianii, Proc. Soc. Exp. Biol. Med., 168, 266, 1981.
288. Kirschbaum, N. E. and Budzynski, A. Z., A unique proteolytic fragment of human fibrinogen containing the Aα COOH-terminal domain of the native molecule, J. Biol. Chem., 265, 13669, 1990.
289. Sawyer, R. T., Munro, R., and Jones, C. P., A novel thrombolytic directed against platelet-rich clots, Thromb. Haem., 65(6), 1191, 1991.
290. Malinconico, S. M., Katz, J. B., and Budzynski, A. Z., Hementin: anticoagulant protease from the salivary gland of the leech Haementeria ghilianii, J. Lab. Clin. Med., 103, 44, 1984.
291. Calbiochem catalog, San Diego, CA, 1994/5.
292. Electricwala, A., Sawyer, R. T., and Atkinson, T., Hementin: a novel anticoagulant from leech, Thromb. Haem., 65(6), 1210, 1991.
293. Swadesh, J. K., Huang, I.-Y., and Budzynski, A. Z., Purification and characterization of hementin, a fibrinogenolytic protease from the leech Haementeria ghilianii, J. Chromatogr., 502, 359, 1990.