Modification of TiO2 nanotube surfaces by electro-spray deposition of amoxicillin combined with PLGA for bactericidal effects at surgical implantation sites

Acta Odontologica Scandinavica

Volumn 71, Issue 1, 2013, Pages 168-174

  Lee, Jung Hwan ^a   Moon, Seung Kyun ^a   Kim, Kwang Mahn ^a   Kim, Kyoung Nam ^a  

^a Yonsei University College of Dentistry   (South Korea)

Author keywords

Amoxicillin; Electro spray deposition; Implant surface coating; PLGA

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; BIOMATERIAL; LACTIC ACID; NANOTUBE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TITANIUM; TITANIUM DIOXIDE;

ANIMAL; ARTICLE; BONE PLATE; CELL ADHESION; CELL PROLIFERATION; CELL STRAIN 3T3; DRUG COMBINATION; DRUG EFFECT; INFRARED SPECTROSCOPY; METHODOLOGY; MICROBIOLOGY; MOUSE; OSTEOBLAST; SPECTROPHOTOMETRY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SURFACE PROPERTY; TOOTH IMPLANT; TOOTH IMPLANTATION;

3T3 CELLS; AMOXICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; BONE PLATES; CELL ADHESION; CELL PROLIFERATION; COATED MATERIALS, BIOCOMPATIBLE; DENTAL IMPLANTATION, ENDOSSEOUS; DENTAL IMPLANTS; DRUG COMBINATIONS; LACTIC ACID; MICE; NANOTUBES; OSTEOBLASTS; POLYGLYCOLIC ACID; SPECTROPHOTOMETRY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SURFACE PROPERTIES; TITANIUM;

EID: 84871485661     PISSN: 00016357     EISSN: 15023850     Source Type: Journal    
DOI: 10.3109/00016357.2011.654256     Document Type: Article

References (19)

1. Communications ADo. Dental implants-An option for replacing missing teeth. J Am Dent Assoc 2005;136:255.
2. Darouiche RO. Current concepts-. Treatment of infections associated with surgical implants. N Engl J Med 2004; 350:1422-9.
3. Geisler S. Orally administered amoxicillin decreases the risk of implant failures. J Am Dent Assoc 2009;140:1294-6.
4. Moulari B, Lboutounne H, Chaumont JP, Guillaume Y, Millet J, Pellequer Y. Potentiation of the bactericidal activity of Harungana madagascariensis Lam. ex Poir. (Hypericaceae) leaf extract against oral bacteria using poly (D, L-lactide-coglycolide) nanoparticles: in vitro study. Acta Odontol Scand 2006;64:153-8.
5. Lee SY, Koak JY, Heo SJ, Kim SK, Lee SJ, Nam SY. Osseointegration of anodized titanium implants coated with poly(lactide-co-glycolide)/basic fibroblast growth factor by electrospray. Int J Oral Maxillofac Implants 2010; 25:315-20.
6. Anderson JM, Shive MS. Biodegradation and biocompatibility of PLA and. PLGA microspheres. Adv Drug Deliv Rev 1997;28:5-24.
7. Ali G, Chen C, Yoo SH, Kum JM, Cho SO. Fabrication of complete titania nanoporous structures via electrochemical anodization of Ti. Nanoscale Res Letts 2011;6:332
8. Westergard R, Hogmark S, Vuoristo P. Tribological properties of sprayed alumina coatings sealed by electro-deposition of Cu. Wear 2004;256:1163-75.
9. Moogooee M, Ramezanzadeh H, Jasoori S, Omidi Y, Davaran S. Synthesis and in vitro studies of cross-linked hydrogel nanoparticles containing amoxicillin. J Pharm Sci 2011;100:1057-66.
10. Astete CE, Sabliov CM. Synthesis and characterization of PLGA nanoparticles. J Biomater Sci Polym Ed 2006;17:247-89.
11. Drugs.com [Internet]. Maryland: The American Society of Health-System Pharmacists, Inc.; 20814 [updated 2008 May]. Available online at http://www.drugs.com/monograph/amoxicillin.html.Accessed 27 July 2011.
12. Bebu A, Szabo L, Leopold N, Berindean C, David L. IR, Raman, SERS and DFT study of amoxicillin. J Mol Struct 2011;993:52-6.
13. Fan YB, Xiu KH, Dong X, Zhang M. The influence of mechanical loading on osseointegration: an animal study. Sci China C Life Sci 2009;52:579-86.
14. Kronstrom M, Svenson B, Hellman M, Persson GR. Early implant failures in patients treated with Branemark system titanium dental implants: a retrospective study. Int J Oral Maxillofac Implants 2001;16:201-7.
15. Song D-H, Uhm S-H, Lee S-B, Han J-G, Kim K-N. Antimicrobial silver-containing titanium oxide nanocomposite coatings by a reactive magnetron sputtering. Thin Solid Films 2011;519:7079-85.
16. Kim W-H, Lee S-B, Lee Y-K, Kim K-N, Kim K-M. The drug release and antibacterial effects on titanium surface according to biodegradable polymer coating with antibiotics. Korea Res Soc Den Mater 2010;37:39-46.
17. Nablo BJ, Rothrock AR, Schoenfisch MH. Nitric oxidereleasing sol-gels as antibacterial coatings for orthopedic implants. Biomaterials 2005;26:917-24.
18. Siegel SJ, Kahn JB, Metzger K,Winey KI, Werner K, Dan N. Effect of drug type on the degradation rate of PLGA matrices. Eur J Pharm Biopharm 2006;64:287-93.
19. Lu L, Peter SJ, LymanMD, LaiHL, Leite SM,Tamada JA, et al. In vitro and in vivo degradation of porous poly(DL-lactic-coglycolic acid) foams. Biomaterials 2000;21:1837-45.