Morphometric analysis of postoperative corneal neovascularization after high-risk keratoplasty: Herpetic versus non-herpetic disease

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 250, Issue 11, 2012, Pages 1663-1671

  Altenburger, Amadeus E ^a   Bachmann, Björn ^a   Seitz, Berthold ^b   Cursiefen, Claus ^a,c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Angiogenic stimulus; Corneal neovascularization; Herpes simplex virus; Herpes stromal keratitis; High risk keratoplasty

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORNEA NEOVASCULARIZATION; FEMALE; HERPES SIMPLEX KERATITIS; HUMAN; KERATOPLASTY; MALE; MORPHOMETRICS; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RISK FACTOR; SURGICAL RISK;

ADULT; AGED; AGED, 80 AND OVER; CORNEAL NEOVASCULARIZATION; CORNEAL STROMA; FEMALE; HUMANS; INCIDENCE; KERATITIS, HERPETIC; KERATOPLASTY, PENETRATING; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84871461531     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-012-1988-6     Document Type: Article

References (42)

1. Streilein JW, Dana MR, Ksander BR (1997) Immunity causing blindness: five different paths to herpes stromal keratitis. Immunol Today 18:443-449
2. Liesegang TJ (2001) Herpes simplex virus epidemiology and ocular importance. Cornea 20:1-13
3. Deshpande S, Banerjee K, Biswas PS, Rouse BT (2004) Herpetic eye disease: immunopathogenesis and therapeutic measures. Expert Rev Mol Med 6:1-14
4. Biswas PS, Rouse BT (2005) Early events in HSV keratitis - setting the stage for a blinding disease. Microbes Infect 7:799-810
5. Russell RG, Nasisse MP, Larsen HS, Rouse BT (1984) Role of Tlymphocytes in the pathogenesis of herpetic stromal keratitis. Invest Ophthalmol Vis Sci 25:938-944
6. Thomas J, Rouse BT (1997) Immunopathogenesis of herpetic ocular disease. Immunol Res 16:375-386
7. Lepisto AJ, Frank GM, Hendricks RL (2007) How herpes simplex virus type 1 rescinds corneal privilege. Chem Immunol Allergy 92:203-212
8. Sottile J (2004) Regulation of angiogenesis by extracellular matrix. Biochim Biophys Acta 1654:13-22
9. Kaye S, Choudhary A (2006) Herpes simplex keratitis. Prog Retin Eye Res 25:355-380
10. Cursiefen C, Kruse FE (2006) New aspects of angiogenesis in the cornea. In: Reinhard T, Larkin F (eds) Cornea and external eye disease (Essentials in ophthalmology). Springer, Heidelberg
11. Zheng M, Deshpande S, Lee S, Ferrara N, Rouse BT (2001) Contribution of vascular endothelial growth factor in the neovascularization process during the pathogenesis of herpetic stromal keratitis. J Virol 75:9828-9835
12. Zheng M, Schwarz MA, Lee S, Kumaraguru U, Rouse BT (2001) Control of stromal keratitis by inhibition of neovascularization. Am J Pathol 159:1021-1029
13. Hayashi K, Hooper LC, Chin MS, Nagineni CN, Detrick B, Hooks JJ (2006) Herpes simplex virus 1 (HSV-1) DNA and immune complex (HSV-1-human IgG) elicit vigorous interleukin 6 release from infected corneal cells via Toll-like receptors. J Gen Virol 87:2161-2169
14. Shimomura Y, Deai T, Fukuda M, Higaki S, Hooper LC, Hayashi K (2007) Corneal buttons obtained from patients with HSK harbor high copy numbers of the HSV genome. Cornea 26:190-193
15. Hayashi K, Hooper LC, Detrick B, Hooks JJ (2009) HSV immune complex (HSV-IgG: IC) and HSV-DNA elicit the production of angiogenic factor VEGF and MMP-9. Arch Virol 154:219-226
16. Cursiefen C, Chen L, Dana MR, Streilein JW (2003) Corneal lymphangiogenesis: evidence, mechanisms, and implications for corneal transplant immunology. Cornea 22:273-281
17. Shtein RM, Elner VM (2010) Herpes simplex virus keratitis: histopathology and corneal allograft outcomes. Expert Rev Ophthalmol 5:129-134
18. Maguire MG, Stark WJ, Gottsch JD, Stulting RD, Sugar A, Fink NE, Schwartz A (1994) Risk factors for corneal graft failure and rejection in the collaborative corneal transplantation studies. Collaborative Corneal Transplantation Studies Research Group. Ophthalmology 101:1536-1547
19. Shtein RMGD, Mush DC, Elner VM (2008) HSV keratitis: histopathologic predictors of corneal allograft complications. Trans Am Ophthalmol Soc 106:161-170
20. Dana MR, Streilein JW (1996) Loss and restoration of immune privilege in eyes with corneal neovascularization. Invest Ophthalmol Vis Sci 37:2485-2494
21. Bachmann BO, Bock F,Wiegand SJ,Maruyama K, DanaMR, Kruse FE, Luetjen-Drecoll E, Cursiefen C (2008) Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation. Arch Ophthalmol 126:71-77
22. Foster CS, Duncan J (1981) Penetrating keratoplasty for herpes simplex keratitis. Am J Ophthalmol 92:336-343
23. Nicholls SM, Shimeld C, Easty DL, Hill TJ (1996) Recurrent herpes simplex after corneal transplantation in rats. Invest Ophthalmol Vis Sci 37:425-435
24. Hill JC (2002) High risk corneal grafting. Br J Ophthalmol 86:945
25. Garcia DD, Shtein RM, Musch DC, Elner VM (2009) Herpes simplex virus keratitis: histopathologic neovascularization and corneal allograft failure. Cornea 28:963-965
26. Cursiefen C, Cao J, Chen L, Liu Y, Maruyama K, Jackson D, Kruse FE, Wiegand SJ, Dana MR, Streilein JW (2004) Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. Invest Ophthalmol Vis Sci 45:2666-2673
27. Cursiefen C, Martus P, Nguyen NX, Langenbucher A, Seitz B, Kuchle M (2002) Corneal neovascularization after nonmechanical versus mechanical corneal trephination for non-high-risk keratoplasty. Cornea 21:648-652
28. Lam VM, Nguyen NX, Martus P, Seitz B, Kruse FE, Cursiefen C (2006) Surgery-related factors influencing corneal neovascularization after low-risk keratoplasty. Am J Ophthalmol 141:260-266
29. Cursiefen C, Wenkel H, Martus P, Langenbucher A, Nguyen NX, Seitz B, Kuchle M, Naumann GO (2001) Impact of short-term versus long-term topical steroids on corneal neovascularization after non-high-risk keratoplasty. Graefes Arch Clin Exp Ophthalmol 239:514-521
30. Cursiefen C, Wenkel H, Martus P, Langenbucher A, Seitz B, Kuchle M (2001) Standardized semiquantitative analysis of corneal neovascularization using projected corneal photographs-pilot study after perforating corneal keratoplasty before immune reaction. Klin Monatsbl Augenheilkd 218:484-491
31. Streilein JW (2003) Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat Rev Immunol 3:879- 889
32. Gerten G (2008) Bevacizumab (avastin) and argon laser to treat neovascularization in corneal transplant surgery. Cornea 27:1195- 1199
33. Bachmann B, Taylor RS, Cursiefen C (2010) Corneal neovascularization as a risk factor for graft failure and rejection after keratoplasty: an evidence-based meta-analysis. Ophthalmology 117:1300- 1305
34. Hayashi K, Hooper LC, Hooks JJ (2008) Who (what) pays toll for the development of herpetic stromal keratitis (HSK). Semin Ophthalmol 23:229-234
35. Remeijer L, Duan R, van Dun JM, Wefers Bettink MA, Osterhaus AD, Verjans GM (2009) Prevalence and clinical consequences of herpes simplex virus type 1 DNA in human cornea tissues. J Infect Dis 200:11-19
36. Remeijer L, Doornenbal P, Geerards AJ, Rijneveld WA, Beekhuis WH (1997) Newly acquired herpes simplex virus keratitis after penetrating keratoplasty. Ophthalmology 104:648-652
37. Rezende RA, Uchoa UB, Raber IM, Rapuano CJ, Laibson PR, Cohen EJ (2004) New onset of herpes simplex virus epithelial keratitis after penetrating keratoplasty. Am J Ophthalmol 137:415-419
38. Kaye SB, Lynas C, Patterson A, Risk JM, McCarthy K, Hart CA (1991) Evidence for herpes simplex viral latency in the human cornea. Br J Ophthalmol 75:195-200
39. Biswas S, Suresh P, Bonshek RE, Corbitt G, Tullo AB, Ridgway AE (2000) Graft failure in human donor corneas due to transmission of herpes simplex virus. Br J Ophthalmol 84:701-705
40. Cleator GM, Klapper PE, Dennett C, Sullivan AL, Bonshek RE, Marcyniuk B, Tullo AB (1994) Corneal donor infection by herpes simplex virus: herpes simplex virus DNA in donor corneas. Cornea 13:294-304
41. Garweg JG, Russ CE, Schellhorn M, Bohnke M, Halberstadt M (2003) HSV-1 antigens and DNA in the corneal explant buttons of patients with non-herpetic or clinically atypical herpetic stromal keratitis. Graefes Arch Clin Exp Ophthalmol 241:734- 739
42. Dana MR, Schaumberg DA, Kowal VO, Goren MB, Rapuano CJ, Laibson PR, Cohen EJ (1995) Corneal neovascularization after penetrating keratoplasty. Cornea 14:604-609