Invasive African nontyphoidal Salmonella requires high levels of complement for cell-free antibody-dependent killing

Journal of Immunological Methods

Volumn 387, Issue 1-2, 2013, Pages 121-129

  Goh, Yun Shan ^a   MacLennan, Calman A ^a,b  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Complement; Salmonella; Serum bactericidal assay

Indexed keywords

ANTIBODY; COMPLEMENT;

ARTICLE; ASSAY; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; HUMAN; NONHUMAN; NONTYPHOIDAL ISOLATES OF SALMONELLA; PRIORITY JOURNAL; SALMONELLA; SALMONELLA PARATYPHI; SALMONELLA TYPHIMURIUM; SERUM BACTERICIDAL ASSAY;

ADULT; AFRICA; ANIMALS; ANTIBODIES, BACTERIAL; COMPLEMENT SYSTEM PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LIPOPOLYSACCHARIDES; MICROBIAL VIABILITY; RABBITS; SALMONELLA; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; SALMONELLA VACCINES; SERUM BACTERICIDAL ANTIBODY ASSAY; SPECIES SPECIFICITY;

BACTERIA (MICROORGANISMS); BOVINE RESPIRATORY SYNCYTIAL VIRUS; NEGIBACTERIA; ORYCTOLAGUS CUNICULUS; SALMONELLA; SALMONELLA PARATYPHI; SALMONELLA TYPHIMURIUM;

EID: 84871451385     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2012.10.005     Document Type: Article

References (29)

1. Acharya I.L., Lowe C.U., Thapa R., Gurubacharya V.L., Shrestha M.B., Cadoz M., Schulz D., Armand J., Bryla D.A., Trollfors B., et al. Prevention of typhoid fever in Nepal with the Vi capsular polysaccharide of Salmonella typhi. A preliminary report. N. Engl. J. Med. 1987, 317:1101.
2. Baumler A.J., Tsolis R.M., Ficht T.A., Adams L.G. Evolution of host adaptation in Salmonella enterica. Infect. Immun. 1998, 66:4579.
3. Berkley J.A., Lowe B.S., Mwangi I., Williams T., Bauni E., Mwarumba S., Ngetsa C., Slack M.P., Njenga S., Hart C.A., Maitland K., English M., Marsh K., Scott J.A. Bacteremia among children admitted to a rural hospital in Kenya. N. Engl. J. Med. 2005, 352:39.
4. Boyle E.C., Bishop J.L., Grassl G.A., Finlay B.B. Salmonella: from pathogenesis to therapeutics. J. Bacteriol. 2007, 189:1489.
5. Brent A.J., Oundo J.O., Mwangi I., Ochola L., Lowe B., Berkley J.A. Salmonella bacteremia in Kenyan children. Pediatr. Infect. Dis. J. 2006, 25:230.
6. Bronzan R.N., Taylor T.E., Mwenechanya J., Tembo M., Kayira K., Bwanaisa L., Njobvu A., Kondowe W., Chalira C., Walsh A.L., Phiri A., Wilson L.K., Molyneux M.E., Graham S.M. Bacteremia in Malawian children with severe malaria: prevalence, etiology, HIV coinfection, and outcome. J. Infect. Dis. 2007, 195:895.
7. Dulaney A.D. Complement activity of human serum with especial reference to malaria. Fed. Proc. 1947, 6:425.
8. Everest P., Wain J., Roberts M., Rook G., Dougan G. The molecular mechanisms of severe typhoid fever. Trends Microbiol. 2001, 9:316.
9. Frasch C.E., Borrow R., Donnelly J. Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease. Vaccine 2009, 27(Suppl. 2):B112-B116.
10. Gat O., Galen J.E., Tennant S., Simon R., Blackwelder W.C., Silverman D.J., Pasetti M.F., Levine M.M. Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines. PLoS Negl. Trop. Dis. 2011, 5:e1373.
11. Graham S.M. Salmonellosis in children in developing and developed countries and populations. Curr. Opin. Infect. Dis. 2002, 15:507.
12. Graham S.M. Nontyphoidal salmonellosis in Africa. Curr. Opin. Infect. Dis. 2010, 23:409.
13. Graham S.M., Hart C.A., Molyneux E.M., Walsh A.L., Molyneux M.E. Malaria and Salmonella infections: cause or coincidence?. Trans. R. Soc. Trop. Med. Hyg. 2000, 94:227.
14. Ho D.K., Jarva H., Meri S. Human complement factor H binds to outer membrane protein rck of Salmonella. J. Immunol. 2010, 185:1763.
15. Hohmann E.L. Nontyphoidal salmonellosis. Clin. Infect. Dis. 2001, 32:263.
16. Hoiseth S.K., Stocker B.A. Aromatic-dependent Salmonella Typhimurium are non-virulent and effective as live vaccines. Nature 1981, 291:238.
17. Jimenez-Lucho V.E., Joiner K.A., Foulds J., Frank M.M., Leive L. C3b generation is affected by the structure of the O-antigen polysaccharide in lipopolysaccharide from salmonellae. J. Immunol. 1987, 139:1253.
18. Kingsley R.A., Msefula C.L., Thomson N.R., Kariuki S., Holt K.E., Gordon M.A., Harris D., Clarke L., Whitehead S., Sangal V., Marsh K., Achtman M., Molyneux M.E., Cormican M., Parkhill J., MacLennan C.A., Heyderman R.S., Dougan G. Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res. 2009, 19:2279.
19. Lieberman M.M., Frank W.J., Brady A.V. Protective mechanism of the immune response to a ribosomal vaccine from Pseudomonas aeruginosa. II. In vitro bactericidal and opsonophagocytic studies with specific antiserum. J. Surg. Res. 1988, 44:251.
20. MacLennan C.A., Gondwe E.N., Msefula C.L., Kingsley R.A., Thomson N.R., White S.A., Goodall M., Pickard D.J., Graham S.M., Dougan G., Hart C.A., Molyneux M.E., Drayson M.T. The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children. J. Clin. Invest. 2008, 118:1553.
21. Mastroeni P., Villarreal-Ramos B., Hormaeche C.E. Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells. Infect. Immun. 1993, 61:3981.
22. McSorley S.J., Jenkins M.K. Antibody is required for protection against virulent but not attenuated Salmonella enterica serovar Typhimurium. Infect. Immun. 2000, 68:3344.
23. Mirza S.H., Beeching N.J., Hart C.A. Multi-drug resistant typhoid: a global problem. J. Med. Microbiol. 1996, 44:317.
24. Pulickal A.S., Gautam S., Clutterbuck E.A., Thorson S., Basynat B., Adhikari N., Makepeace K., Rijpkema S., Borrow R., Farrar J.J., Pollard A.J. Kinetics of the natural, humoral immune response to Salmonella enterica serovar typhi in Kathmandu, Nepal. Clin. Vaccine Immunol. 2009, 16:1413.
25. Rychlik I., Gregorova D., Hradecka H. Distribution and function of plasmids in Salmonella enterica. Vet. Microbiol. 2006, 112:1.
26. Siddique M.E., Ahmed S. Serum complement C4 levels during acute malarial infection and post-treatment period. Indian J. Pathol. Microbiol. 1995, 38:335.
27. Siggins M.K., Cunningham A.F., Marshall J.L., Chamberlain J.L., Henderson I.R., MacLennan C.A. Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody. J. Immunol. 2011, 186:2365.
28. Tsai C.M., Frasch C.E. A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. Anal. Biochem. 1982, 119:115.
29. Zollinger W.D., Mandrell R.E. Importance of complement source in bactericidal activity of human antibody and murine monoclonal antibody to meningococcal group B polysaccharide. Infect. Immun. 1983, 40:257.