Meta-analysis of the alpha/beta ratio for prostate cancer in the presence of an overall time factor: Bad news, good news, or no news?

International Journal of Radiation Oncology Biology Physics

Volumn 85, Issue 1, 2013, Pages 89-94

  Vogelius, Ivan R ^a   Bentzen, Soren M ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFIDENCE INTERVAL; DOSE FRACTIONATION; EXTERNAL BEAM; EXTERNAL BEAM RADIATION THERAPY; META-ANALYSIS; OVERALL TREATMENT TIME; PROSTATE CANCERS; SEPARATE ANALYSIS; TIME FACTORS;

DISEASES; ESTIMATION; UNCERTAINTY ANALYSIS;

FACTOR ANALYSIS;

ANDROGEN DEPRIVATION THERAPY; ARTICLE; CANCER RADIOTHERAPY; CELL PROLIFERATION; EXTERNAL BEAM RADIOTHERAPY; HUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME;

CELL SURVIVAL; CONFIDENCE INTERVALS; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; MALE; PROSPECTIVE STUDIES; PROSTATIC NEOPLASMS; RADIATION TOLERANCE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 84871382056     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.03.004     Document Type: Article

References (20)

1. J.F. Fowler, and M.A. Ritter A rationale for fractionation for slowly proliferating tumors such as prostatic adenocarcinoma Int J Radiat Oncol Biol Phys 32 1995 521 529
2. D.J. Brenner, and E.J. Hall Fractionation and protraction for radiotherapy of prostate carcinoma Int J Radiat Oncol Biol Phys 43 1999 1095 1101 (Pubitemid 29144800)
3. J.Z. Wang, M. Guerrero, and X.A. Li How low is the alpha/beta ratio for prostate cancer? Int J Radiat Oncol Biol Phys 55 2003 194 203 (Pubitemid 36020360)
4. D.J. D'Ambrosio, T. Li, and E.M. Horwitz Does treatment duration affect outcome after radiotherapy for prostate cancer? Int J Radiat Oncol Biol Phys 72 2008 1402 1407
5. H.D. Thames, D. Kuban, and L.B. Levy The role of overall treatment time in the outcome of radiotherapy of prostate cancer: an analysis of biochemical failure in 4839 men treated between 1987 and 1995 Radiother Oncol 96 2010 6 12
6. M. Baumann, T. Holscher, and J. Denham Fractionation in prostate cancer - is it time after all? Radiother Oncol 96 2010 1 5
7. P. Diez, I.S. Vogelius, and S.M. Bentzen A new method for synthesizing radiation dose-response data from multiple trials applied to prostate cancer Int J Radiat Oncol Biol Phys 77 2010 1066 1071
8. S.M. Bentzen, and S.L. Tucker Quantifying the position and steepness of radiation dose-response curves Int J Radiat Biol 71 1997 531 542 (Pubitemid 27229750)
9. I.R. Vogelius, and S.M. Bentzen In response to Dr. Williams Int J Radiat Oncol Biol Phys 80 2010 639 640
10. R. Miralbell, S.A. Roberts, and E. Zubizarreta Dose-fractionation sensitivity of prostate cancer deduced from radiotherapy outcomes of 5969 patients in seven international institutional datasets: alpha/beta = 1.4 (0.9-2.2) Gy Int J Radiat Oncol Biol Phys 82 2012 e17 e24
11. The Cochrane Collaboration Review Manager (RevMan) [computer program] 2008 The Nordic Cochrane Centre Copenhagen
12. G. Arcangeli, B. Saracino, and S. Gomellini A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer Int J Radiat Oncol Biol Phys 78 2010 11 18
13. F. Leborgne, J. Fowler, and J.H. Leborgne Later outcomes and alpha/beta estimate from hypofractionated conformal three-dimensional radiotherapy versus standard fractionation for localized prostate cancer Int J Radiat Oncol Biol Phys 82 2012 1200 1207
14. H. Lukka, C. Hayter, and J.A. Julian Randomized trial comparing two fractionation schedules for patients with localized prostate cancer J Clin Oncol 23 2005 6132 6138
15. R. Valdagni, C. Italia, and P. Montanaro Is the alpha-beta ratio of prostate cancer really low? A prospective, non-randomized trial comparing standard and hyperfractionated conformal radiation therapy Radiother Oncol 75 2005 74 82 (Pubitemid 40616798)
16. E.E. Yeoh, R.J. Botten, J. Butters, A.C. Di Matteo, R.H. Holloway, and J. Fowler Hypofractionated versus conventionally fractionated radiotherapy for prostate carcinoma: final results of phase III randomized trial Int J Radiat Oncol Biol Phys 81 5 2011 December 1 1271 1278
17. J.L. Tang Weighting bias in meta-analysis of binary outcomes J Clin Epidemiol 53 2000 1130 1136
18. C. Proust-Lima, J.M. Taylor, and S. Secher Confirmation of a low alpha/beta ratio for prostate cancer treated by external beam radiation therapy alone using a post-treatment repeated-measures model for PSA dynamics Int J Radiat Oncol Biol Phys 79 2011 195 201
19. S.G. Williams, J.M. Taylor, and N. Liu Use of individual fraction size data from 3756 patients to directly determine the alpha/beta ratio of prostate cancer Int J Radiat Oncol Biol Phys 68 2007 24 33 (Pubitemid 46589844)
20. V.S. Khoo, and D.P. Dearnaley Question of dose, fractionation and technique: ingredients for testing hypofractionation in prostate cancer - the CHHiP trial Clin Oncol (R Coll Radiol) 20 2008 12 14