Can intake of extra antioxidants delay the development and progression of atherosclerosis?

Atherosclerosis

Volumn 226, Issue 1, 2013, Pages 43-44

  Fuchs, Dietmar ^a   Sperner Unterweger, Barbara ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Antioxidants; Cardiovascular risk; Disease prevention; Food supplements; Immune activation; Macrophages; Oxidative stress

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BENZOIC ACID; BETA CAROTENE; CAROTENOID; LYCOPENE; RETINOL; SODIUM SULFITE; VITAMIN B GROUP;

ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; DISEASE COURSE; FOOD INTAKE; FRUIT; HUMAN; IMMUNE SYSTEM; KAPLAN MEIER METHOD; MORTALITY; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; SUDDEN DEATH; SUPPLEMENTATION; VEGETABLE;

BETA CAROTENE; DEATH, SUDDEN, CARDIAC; HUMANS; MALE;

EID: 84871375291     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.08.019     Document Type: Note

References (15)

1. Libby P., Ridker P.M., Hansson G.K. Progress and challenges in translating the biology of atherosclerosis. Nature 2011, 473:317-325.
2. Conen D., Ridker P.M. Clinical significance of high-sensitivity C-reactive protein in cardiovascular disease. Biomarkers Med 2007, 1:229-241.
3. Schroecksnadel K., Frick B., Winkler C., Fuchs D. Crucial role of interferon-γ and stimulated macrophages in cardiovascular disease. Curr Vasc Pharmacol 2006, 4:205-213.
4. Pedersen E.R., Midttun Ø., Ueland P.M., et al. Systemic markers of interferon-γ-mediated immune activation and long-term prognosis in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol 2011, 31:698-704.
5. Huber C., Batchelor J.R., Fuchs D., et al. Immune response-associated production of neopterin - release from macrophages primarily under control of interferon-gamma. J Exp Med 1984, 160:310-316.
6. Wirleitner B., Reider D., Ebner S., et al. Monocyte-derived dendritic cells release neopterin. J Leukoc Biol 2002, 72:1148-1153.
7. Nathan C.F., Murray H.W., Wiebe M.E., Rubin B.Y. Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med 1983, 158:670-689.
8. Boeing H., Bechthold A., Bub A., et al. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr 2012, 51:637-663.
9. Jenny M., Klieber M., Zaknun D., et al. In vitro testing for anti-inflammatory properties of compounds employing peripheral blood mononuclear cells freshly isolated from healthy donors. Inflamm Res 2011, 60:127-135.
10. Farias M.S., Budni P., Ribeiro C.M., et al. Antioxidant supplementation attenuates oxidative stress in chronic hepatitis C patients. Gastroenterol Hepatol 2012, 35:386-394.
11. Murr C., Winklhofer-Roob B.M., Schroecksnadel K., et al. Inverse association between serum concentrations of neopterin and antioxidants in patients with and without angiographic coronary artery disease. Atherosclerosis 2009, 202:543-549.
12. Karppia J., Laukkanena J.A., Mäkikallio T.H., Ronkainen K., Kurl K. Serum β-carotene and the risk of sudden cardiac death in men: a population-based follow-up study. Atherosclerosis 2013, 226(1):170-175.
13. Campbell D.R., Gross M.D., Martini M.C., Grandits G.A., Slavin J.L., Potter J.D. Plasma carotenoids as biomarkers of vegetable and fruit intake. Cancer Epidemiol Biomarkers Prev 1994, 3:493-500.
14. Kritharides L., Stocker R. The use of antioxidant supplements in coronary heart disease. Atherosclerosis 2002, 164:211-219.
15. Kaliora A.C., Dedoussis G.V., Schmidt H. Dietary antioxidants in preventing atherogenesis. Atherosclerosis 2006, 187:1-17.