Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: Methanolic extracts of novel plants for the management of sickle cell anemia disease

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Afolabi, Israel Sunmola ^a   Osikoya, Iyanuoluwa Olubukola ^a   Fajimi, Oluwabukunmi Dorcas ^a   Usoro, Priscilla Ibanga ^a   Ogunleye, Damilola Olufunlayo ^a   Bisi Adeniyi, Tolulope ^a   Adeyemi, Alaba O ^a   Adekeye, Bosede Temitope ^a  

^a College of Science and Technology Biochemistry Unit ^*  (Nigeria)

Author keywords

Antisickling; Health; Management; Plants; Sickle cell disease; Underutilized

Indexed keywords

ANTIANEMIC AGENT; CARICA PAPAYA EXTRACT; CATALASE; GLUTATHIONE; HEMOGLOBIN; IPOMOEA INVOLUCRATA EXTRACT; LACTATE DEHYDROGENASE; PLANT EXTRACT; SOLENOSTEMON MONOSTACHYUS EXTRACT; UNCLASSIFIED DRUG; VEGETABLE OIL; VERNONIA AMYGDALINA EXTRACT;

ARTICLE; BLOOD CELL; BLOOD SAMPLING; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; GYMNANTHEMUM AMYGDALINUM; HEMATOCRIT; HUMAN; IN VITRO STUDY; IPOMOEA INVOLUCRATA; MALE; MEDICINAL PLANT; NUTRITIONAL STATUS; PAPAYA; PLANT SEED; POLYMERIZATION; SICKLE CELL ANEMIA; SOLENOSTEMON MONOSTACHYUS;

ANEMIA, SICKLE CELL; ANTISICKLING AGENTS; CARICA; CATALASE; ERYTHROCYTES; FEMALE; GLUTATHIONE; HEMOGLOBINS; HUMANS; IPOMOEA; L-LACTATE DEHYDROGENASE; LAMIACEAE; MALE; PLANT EXTRACTS; PLANT OILS; VERNONIA;

EID: 84871366510     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-262     Document Type: Article

References (44)

1. Okpuzor J, Adebesin O, Ogbunugafor H, Amadi I. The potential of medicinal plants in sickle cell disease control: a review. Int J Biomed Health Sci 2008, 4(2):47-55.
2. WHO Guidelines on developing consumer on proper use of traditional, complementary and alternative medicine. The report of WHO Consultation on Proper Use of Traditional Medicine and Complementary Medicine by Consumers held at Milan, Italy, 1-3 December 2003. Edited by WHO, vol. 1, First edn. Milan (Italy) 2004, 87. Milan (Italy): World Health Organisation (WHO), 1, WHO.
3. Elujoba AA, Odeleye OM, Ogunyemi CM. Traditional medicine development for medical and dental primary health care delivery system in Africa. Afr J Tradit Complement Altern Med 2005, 2:46-61.
4. Dapa D, Gil T. Sickle cell disease in Africa. Curr Opinin Haematol 2002, 9:111-116.
5. Mpiana PT, Ngbolua KN, Mudogo V, Tshibangu DST, Atibu EK, Tshilanda DD, Misengabu NM. Anti sickle erythrocytes haemolysis properties and inhibitory effect of anthocyanins extracts of Trema orientalis (Ulmaceae) on the aggregation of human deoxyhemoglobin S in vitro. J Med Sci 2011, 11:129-137.
6. Iyamu EW, Ernest A, Toshio A. Niprisan (Nix-0699) improves the survival rates of transgenic sickle cell mice under acute severe hypoxic conditions. Br J Haematol 2003, 122:1001-1008. 10.1046/j.1365-2141.2003.04536.x, 12956772.
7. Brugnara C, De Franceshi L, Alper SL. Inhibition of Ca2+ dependent K+ transport and cell dehydration in sickle erythryocytes by CLT and other imidazole derivatives. J Clin Invest 1993, 92:520-526. 10.1172/JCI116597, 293641, 8326017.
8. Ekeke GI, Uwakwe AA, Nwaoguikpe R. The action of ripe fruit juices on hemoglobin polymerization, Fe2+/Fe3+ ratio and lactate dehydrogenase activity of sickle cell (HbSS) blood. Nig J Biochem Mol Biol 2001, 16(1):31-35.
9. Nwaoguikpe RN, Braide W. Some fruit juices as environmental sickling agents. World J Med Sci 2010, 5:98-104.
10. Nwaoguike RN, Uwakwe AA. The antisickling effects of dried fish (tilapia) and dried prawn (Astacus red). J Appl Sci Environ Manage 2005, 9:115-119.
11. Afolabi IS, Akuiyibo SM, Rotimi SO, Adeyemi AO. In vivo evaluation of lipid and antioxidants qualities of Carica papaya seed oil. J Nat Prod 2011, 4:125-135.
12. Afolabi IS, Ofobrukweta K. Physicochemical and nutritional qualities of Carica papaya seed products. JMPR 2011, 5(14):3115-3117.
13. Okoko T, Ere D. Antioxidant activities of Solenostemon monostachyus leaf extract using in vitro methods. Sci Res Assays 2012, 7:621.
14. Yeap SK, Ho WY, Beh BK, Liang WS, Ky H, Yousr AHN, Alitheen NB. Vernonia amygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bioactivities. JMPR 2010, 4(25):2787-2812.
15. Ogunyemi CM, Elujoba AA, Durosinmi MA. Antisickling properties of Carica papaya Linn. J Nat Prod 2008, 1:56-66.
16. Sinha KA. Colorimetric assay of Catalase. Anal Biochem 1972, 47:389-394. 10.1016/0003-2697(72)90132-7, 4556490.
17. Wever R, Hamers M, Weening R, Roos D. Characterization of the peroxidase in human eosinophils. Eur J Biochem 1980, 108:491-505. 10.1111/j.1432-1033.1980.tb04746.x, 6250833.
18. Garner C, Tatu T, Reittie JE, Littlewood T, Darley J, Cervino S, Farrall M, Kelly P, Spector TD, Thein SL. Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood 2000, 95(1):342-346.
19. Akinnuga AM, Bamidele O, Chukwuebuka IC. Correlation between packed cell volume and body mass index in hypertensive and normotensive subjects. Ann Biol Res 2011, 2(2):65-71.
20. Tirlapur VG, Gicheru K, Charalambous BM, Evans PJ, Mir MA. Packed cell volume, haemoglobin, and oxygen saturation changes in healthy smokers and non-smokers. Thorax 1983, 38:785-787. 10.1136/thx.38.10.785, 459657, 6648858.
21. McCurdy PR, Mahmood L, Sherman AS. Red cell life span in sickle cell-hemoglobin C disease with a note about sickle cell-hemoglobin O ARAB. Blood 1975, 45:273-279.
22. Milner PF, Charache S. Life span of carbamylated red cells in sickle cell anemia. J Clin Invest 1973, 52(12):3161-3171. 10.1172/JCI107516, 302592, 4750447.
23. Shimizu H, Tamam M, Soemantri A, Ishida T. Glucose-6-phosphate dehydrogenase deficiency and Southeast Asian ovalocytosis in asymptomatic plasmodium carriers in Sumba island, Indonesia. J Hum Genet 2005, 50:420-424. 10.1007/s10038-005-0271-7, 16059744.
24. Ferreira A, Marguti I, Bechmann I, Jeney V, Chora T, Palha NR, Rebelo S, Henri A, Beuzard Y, Soares MP. Sickle hemoglobin confers tolerance to plasmodium infection. Cell 2011, 145(3):398-409. 10.1016/j.cell.2011.03.049, 21529713.
25. Simpore J, Liboudo D, Damintoti K, Sawadogo L, Maria E, Binet S, Nitiema H, Ouedraogo P, Pignatelli S, Nikiema J. Glucose-6-phosphate dehydrogenase deficiency and sickle cell disease in Burkina Faso. Pak J Biol Sci 2007, 10:409-414. 10.3923/pjbs.2007.409.414, 19069510.
26. Ekpenyong EA, Eyo JE. Malaria control and treatment strategies among school children in semi-urban tropical communities. West Indian Med J 2008, 57(5):456-461.
27. Yeshiwondim AK, Gopal S, Hailemariam AT, Dengela DO, Patel HP. Spatial analysis of malaria incidence at the village level in areas with unstable transmission in Ethiopia. Int J Health Geogr 2009, 8:5. 10.1186/1476-072X-8-5, 2646707, 19171051.
28. Ayele DG, Zewotir TT, Mwambi HG. Prevalence and risk factors of malaria in Ethiopia. Malar J 2012, 11:195. 10.1186/1475-2875-11-195, 3473321, 22691364.
29. Capellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet 2008, 371:64-65. 10.1016/S0140-6736(08)60073-2, 18177777.
30. Manganelli G, Fico A, Martini G, Filosa S. Discussion on pharmacogenetic interaction in G6PD deficiency and methods to identify potential hemolytic drugs. Cardiovasc Hematol Disord Drug Targets 2010, 10:143. 10.2174/187152910791292547, 20350285.
31. Osuagwu CG. Mechanism of the antisickling effects of Cajanus cajan and phenylalanine. Nig J Biochem Mol Biol 2010, 25:68-71.
32. Nwaoguikpe RN, Ejele EA. Amino acid profile of some anti-sickling plant extracts and their haemoglobin polymerization inhibition. Nig J Biochem Mol Biol 2010, 25(2):53-59.
33. Diamantino T, Amadeu E, Soaresa M, Guilherminoc L. Lactate dehydrogenase activity as an effect criterion in toxicity tests with Daphnia magna Straus. Chemosphere 2001, 45:553-560. 10.1016/S0045-6535(01)00029-7, 11680751.
34. Hamadah K, Basiouny A, Ghoneim KS. Alterations in the lactate dehydrogenase activity of the desert locust Schistocerca gregaria by the wild plant Fagonia bruguieri (Zygophyllaceae). Egypt Acad J Biol Sci 2010, 3:1-9.
35. Lin JP, Zheng G, Joo J, Cupples LA. Genome-wide linkage and association scans for quantitative trait loci of serum lactate dehydrogenase-The framingham heart study. Hum Genom Proteomics 2010, 2010(Article ID 905237):1-5.
36. Al-Jaleel AA-RA, Hussain MK, AL-Fadal SZS. The effect of sex and BMI on the reference values of serum LDH and ACP activities. Kufa Med J 2009, 12(2):143-148.
37. Manca P, Chisu V. Testosterone attenuates morpho-functional alterations by 2-methoxyastradiol exposure and induces differentiation in C6 cells. J Cell Physiol 2011, 226:1510-1518. 10.1002/jcp.22480, 20945387.
38. Qujeq D, Rezvani T. Catalase (antioxidant enzyme) activity in streptozotocin-induced diabetic rats. Int J Diabetes Metabol 2007, 15:22-24.
39. Barp J, Araújo ASR, Fernandes TRG, Rigatto KV, Llesuy S, Belló-Klein A, Singal P. Myocardial antioxidant and oxidative stress changes due to sex hormones. Braz J Med Biol Res 2002, 35:1075-1081. 10.1590/S0100-879X2002000900008, 12219179.
40. Syed DN, Mukhtar H. Gender bias in skin cancer: role of catalase revealed. J Invest Dermatol 2012, 132:512-514. 10.1038/jid.2011.423, 22327263.
41. Dhahbi JM, Tillman JB, Cao S, Mote PL, Walford RL, Spindler SR. Caloric intake alters the efficiency of catalase mRNA translation in the liver of old female mice. J Gerontol Ser A 1998, 53A(3):B180-B185.
42. Al-Abrash A, Al-Quobaili A, Al-Akhras G. Catalase evaluation in different human diseases associated with oxidative. Saudi Med J 2000, 21(9):827.
43. Milton N. Homocysteine Inhibits Hydrogen Peroxide Breakdown by Catalase. Open Enzym Inhib J 2008, 1:34-41.
44. Kapralov A, Vlasova II, Feng W, Maeda A, Walson K, Tyurin VA, Huang Z, Aneja RK, Carcillo J, Bayi{dotless}r H, et al. Peroxidase activity of hemoglobin-haptoglobin complexes. covalent aggregation and oxidative stress in plasma and macrophages. J Biol Chem 2009, 284(44):30395-30407. 10.1074/jbc.M109.045567, 2781594, 19740759.