Expression profiling of claudins in the human gastrointestinal tract in health and during inflammatory bowel disease

Scandinavian Journal of Gastroenterology

Volumn 48, Issue 1, 2013, Pages 58-69

  Lameris, Anke L ^a   Huybers, Sylvie ^a   Kaukinen, Katri ^b,c   Mäkelä, Tuula H ^b   Bindels, René J ^a   Hoenderop, Joost G ^a   Nevalainen, Pasi I ^b,c  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Claudins; Inflammatory bowel disease; Intestine

Indexed keywords

CLAUDIN; CLAUDIN 15; CLAUDIN 2; CLAUDIN 3; CLAUDIN 4; CLAUDIN 7; CLAUDIN 8; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ENTERITIS; FEMALE; GASTROINTESTINAL TRACT; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH;

ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; CLAUDINS; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

EID: 84871360027     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2012.741616     Document Type: Article

References (34)

1. Mitic LL, Van Itallie CM, Anderson JM. Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: Lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 2000; 279:G250-4.
2. Amasheh S, Fromm M, Gunzel D. Claudins of intestine and nephron - a correlation of molecular tight junction structure and barrier function. Acta Physiol (Oxf) 201:133-40.
3. Will C, Fromm M, Muller D. Claudin tight junction proteins: Novel aspects in paracellular transport. Perit Dial Int 2008;28:577-84.
4. Holmes J, Van Itallie C, Rasmussen J, Anderson J. Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns. Gene Expr Patterns 2006;581-8.
5. Angelow S, Yu AS. Claudins and paracellular transport: An update. Curr Opin Nephrol Hypertens 2007;16:459-64. (Pubitemid 47254697)
6. Fujita H,ChibaH,YokozakiH,Sakai N,SugimotoK,Wada T. Differentialexpressionandsubcellular localizationof claudin-7, -8, -12, -13, and -15 along the mouse intestine. J Histochem Cytochem 2006;54:933-44. (Pubitemid 44106871)
7. Rahner C, Mitic LL, Anderson JM. Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Gastroenterology 2001;411-22. (Pubitemid 32147639)
8. Mankertz J, Schulzke JD. Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications. Curr Opin Gastroenterol 2007;23:379-83. (Pubitemid 46878948)
9. Seidler U, Lenzen H, Cinar A, Tessema T, Bleich A, Riederer B. Molecular mechanisms of disturbed electrolyte transport in intestinal inflammation. AnnNY Acad Sci 2006; 1072:262-75. (Pubitemid 44448459)
10. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista Met al. The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009;55:611-22.
11. Markov AG, Veshnyakova A, Fromm M, Amasheh M, AmashehS. Segmentalexpressionof claudinproteinscorrelates with tight junction barrier properties in rat intestine. J Comp Physiol B 180:591-8.
12. Amasheh S, Milatz S, Krug SM, Bergs M, Amasheh M, Schulzke JD, Fromm M. Na+ absorption defends from paracellular back-leakage by claudin-8 upregulation. Biochem Biophys Res Commun 2009;378:45-50.
13. Tatum R, Zhang Y, Salleng K, Lu Z, Lin JJ, Lu Qet al. Renal salt wasting and chronic dehydration in claudin-7-deficient mice. Am J Physiol Renal Physiol 2010;298:F24-34.
14. Christakos S, Dhawan P, Ajibade D, Benn BS, Feng J, Joshi SS Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D. J Steroid Biochem Mol Biol 2010;121:183-7.
15. Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, UchiyamaYet al.Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell 2008;19:1912-21.
16. Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, Hashimoto Net al. Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol 2003;161: 653-60. (Pubitemid 36578587)
17. Acharya P, Beckel J, Ruiz WG, Wang E, Rojas R, Birder L, Apodaca G Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. Am J Physiol Renal Physiol 2004;287:F305-18. (Pubitemid 38943948)
18. Hou J, Renigunta A, Gomes AS, Hou M, Paul DL, Waldegger S, Goodenough DA Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium. Proc Natl Acad Sci USA 2009;106:15350-5.
19. Hou J, Renigunta A, Konrad M, Gomes AS, Schneeberger EE, Paul DLet al. Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex. J Clin Invest 2008;118:619-28. (Pubitemid 351206551)
20. Tamura A, Kitano Y, Hata M, Katsuno T, Moriwaki K, Sasaki Het al. Megaintestine in claudin-15-deficient mice. Gastroenterology 2008;134:523-34.
21. Tamura A, Hayashi H, Imasato M, Yamazaki Y, Hagiwara A, Wada Met al. Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine. Gastroenterology 140:913-23.
22. Hayashi D, Tamura A, Tanaka H, Yamazaki Y, Watanabe S, Suzuki Ket al. Deficiency of claudin-18 causes paracellular H + leakage, up-regulation of interleukin-1beta, and atrophic gastritis in mice. Gastroenterology.
23. Matsuda M, Sentani K, Noguchi T, Hinoi T, Okajima M, Matsusaki Ket al. Immunohistochemical analysis of colorectal cancer with gastric phenotype: Claudin-18 is associated with poor prognosis. Pathol Int 2010;60:673-80.
24. Jovov B, Van Itallie CM, Shaheen NJ, Carson JL, Gambling TM, Anderson JM, Orlando RC Claudin-18: A dominant tight junction protein in Barrett's esophagus and likely contributor to its acid resistance. Am J Physiol Gastrointest Liver Physiol 2007;293:G1106-13. (Pubitemid 350255034)
25. Das P, Goswami P, Das TK, Nag T, Sreenivas V, Ahuja Vet al. Comparative tight junction protein expressions in colonic Crohn's disease, ulcerative colitis, and tuberculosis: A new perspective. Virchows Arch 460:261-70.
26. Oshima T, Miwa H, Joh T. Changes in the expression of claudins in active ulcerative colitis. J Gastroenterol Hepatol 2008;S146-50.
27. Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Lab Invest 2008;88:1110-20.
28. Zeissig S, Bürgel N, Günzel D, Richter J, Mankertz J, Wahnschaffe Uet al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 2007; 61-72. (Pubitemid 46044890)
29. Amasheh S, Dullat S, Fromm M, Schulzke JD, Buhr HJ, Kroesen AJ Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease. Int J Colorectal Dis 2009;24:1149-56.
30. Burgel N, Bojarski C, Mankertz J, Zeitz M, Fromm M, Schulzke JD Mechanisms of diarrhea in collagenous colitis. Gastroenterology 2002;123:433-43. (Pubitemid 34827187)
31. Prasad S, Mingrino R, Kaukinen K, et al. Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. Lab Invest 2005;1139-62. (Pubitemid 43073987)
32. Geboes K. Histopathology of Crohn's disease and ulcerative colitis. In Satsangi JSL, editor. Inflammatory bowel disease. th ed. Churchill Livingstone; Elsevier: 2003. pp 255-76.
33. Fuss IJ, Heller F, Boirivant M, et al. Nonclassical CD1 d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J Clin Invest 2004; 113:1490-7. (Pubitemid 39071705)
34. Wisner DM, Harris LR 3rd, Green CL, et al. Opposing regulation of the tight junction protein claudin-2 by interferongamma and interleukin-4. J Surg Res 2008;144:1-7. (Pubitemid 350234959)