Transient Features in Nanosecond Pulsed Electric Fields Differentially Modulate Mitochondria and Viability

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Beebe, Stephen J ^a   Chen, Yeong Jer ^a   Sain, Nova M ^a   Schoenbach, Karl H ^a,b   Xiao, Shu ^a,b  

^a OLD DOMINION UNIVERSITY   (United States)

^b Old Dominion University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; EGTAZIC ACID; TETRAMETHYLRHODAMINE ETHYL ESTER;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARCINOMA CELL; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONTROLLED STUDY; INTRACELLULAR TRANSPORT; LIGHT SCATTERING; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE; NANOPORE; PULSED ELECTRIC FIELD;

CALCIUM; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; EGTAZIC ACID; ELECTRICITY; HUMANS; LIGHT; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; ORGANOMETALLIC COMPOUNDS; SCATTERING, RADIATION; TIME FACTORS;

EID: 84871357844     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051349     Document Type: Article

References (37)

1. Schoenbach KH, Beebe SJ, Buescher ES, (2001) Intracellular effect of ultrashort electrical pulses. Bioelectromagnetics 22: 440-448.
2. Stewart DA, Gowrishankar TR, Weaver JC, (2004) Transport lattice approach to describing cell electroporation: use of a local asymptotic model. IEEE Trans Plasma Sci 32: 1696-1708.
3. Gowrishankar TR, Esser AT, Vasilkoski Z, Smith KC, Weaver JC, (2006) Microdosimetry for conventional and supra-electroporation in cells with organelles. Biochem Biophys Res Commun 341: 1266-1276.
4. Beebe SJ, Fox PM, Rec LJ, Buescher ES, Somers K, et al. (2002) Nanosecond Pulsed Electric Field (nsPEF) Effects on Cells and Tissues: Apoptosis Induction and Tumor Growth Inhibition. IEEE Trans Plasma Sci 30: 286-292.
5. Beebe SJ, Fox PM, Rec LJ, Willis EL, Schoenbach KH, (2003) Nanosecond, high-intensity pulsed electric fields induce apoptosis in human cells. FASEB J 17: 1493-1495.
6. Vernier PT, Aimin L, Marcu L, Craft CM, Gundersen MA, (2003) Ultrashort pulsed electric fields induce membrane phospholipid translocation and caspase activation: differential sensitivities of Jurkat T lymphoblasts and rat glioma C6 cells. IEEE Trans Dielect Electr Insul 10: 795-809.
7. Chen X, Kolb JF, Swanson RJ, Schoenbach KH, Beebe SJ, (2010) Apoptosis initiation and angiogenesis inhibition: melanoma targets for nanosecond pulsed electric fields. Pigment Cell Melanoma Res 23: 554-563.
8. Chen X, Zhuang J, Kolb JF, Schoenbach KH, Beebe SJ, (2012) Long Term Survival of Mice with Hepatocellular Carcinoma after Pulse Power Ablation with Nanosecond Pulsed Electric Fields. Tech Can Res Treat 11: 83-93.
9. Kotnik T, Miklavcic D, (2006) Theoretical evaluation of voltage inducement on internal membranes of biological cells exposed to electric fields. Biophys J 90: 480-491.
10. Pakhomov AG, Bowman AM, Ibey BL, Andre FM, Pakhomova ON, et al. (2009) Lipid nanopores can form a stable, ion channel-like conduction pathway in cell membrane. Biochem Biophys Res Commun 385: 181-186.
11. Weaver JC, Smith KC, Esser AT, Son RS, Gowrishankar TR, (2012) A brief overview of electroporation pulse strength-duration space: A region where additional intracellular effects are expected. Bioelectrochemistry 2012 87: 236-243.
12. Schoenbach KH (2010) Bioelectric Effect of Intense Nanosecond Pulses. In: Pakhomov AG, Miklavcic D, and Markov MS, editors. Advanced Electroporation Techniques in Biology and Medicine. CRC Press/Taylor and Francis Group. pp. 19-50.
13. Foster HR, Schwan HP (1995) Dielectric Properties of Tissues. In: Polk C and Postow E, editors. Handbook of Biological Effects of Electromagnetic Fields. Boca Racon: CRC Press. 90 p.
14. Pakhomov AG, Kolb JF, White JA, Joshi RP, Xiao S, et al. (2007) Long-lasting plasma membrane permeabilization in mammalian cells by nanosecond pulsed electric field (nsPEF). Bioelectromagnetics 28: 655-663.
15. Davalos RV, Mir IL, Rubinsky B, (2005) Tissue ablation with irreversible electroporation. Ann Biomed Eng 33: 223-31.
16. Ford WE, Ren W, Blackmore PF, Schoenbach KH, Beebe SJ, (2010) Nanosecond pulsed electric fields stimulate apoptosis without release of pro-apoptotic factors from mitochondria in B16f10 melanoma. Arch Biochem Biophys 497: 82-89.
17. Ren W, Beebe SJ, (2011) An apoptosis targeted stimulus with nanosecond pulsed electric fields (nsPEFs) in E4 squamous cell carcinoma. Apoptosis 16: 382-393.
18. Batista Napotnik TB, Wu YH, Gundersen MA, Miklavčič D, Vernier PT, (2012) Nanosecond electric pulses cause mitochondrial membrane permeabilization in Jurkat cells. Bioelectromagnetics 33: 257-264.
19. Vernier PT, Sun Y, Marcu L, Salemi S, Craft CM, et al. (2003) Calcium bursts induced by nanosecond electric pulses. Biochem Biophys Res Commun 310: 286-295.
20. Buescher ES, Smith RR, Schoenbach KH, (2004) Submicrosecond intense pulsed electric field effects on intracellular free calcium: mechanisms and effects. IEEE Trans Plasma Sci 32: 1563-1572.
21. White JA, Blackmore PF, Schoenbach KH, Beebe SJ, (2004) Stimulation of capacitative calcium entry in HL-60 cells by nanosecond pulsed electric fields. J Biol Chem 279: 22964-22972.
22. Zhang J, Blackmore PF, Hargrave BY, Xiao S, Beebe SJ, et al. (2008) Nanosecond pulsed electric field (nanopulse): a novel non-ligand agonist for platelet activation. Arch Biochem Biophys 471: 240-8.
23. Wang S, Chen J, Chen MT, Vernier PT, Gundersen MA, et al. (2009) Cardiac myocyte excitation by ultrashort high-field pulses. Biophys J 96: 1640-1648.
24. Duchen MR, (2000) Mitochondria and calcium: from cell signaling to cell death J Physiol. 529: 57-68.
25. Festjens N, Vanden Berghe T, Vandenabeele P, (2006) Necrosis, a well-orchestrated form of cell demise: signaling cascades, important mediators and concomitant immune response. Biochim Biophys Acta 1757: 1371-87.
26. Galluzzi L, Kroemer G, (2008) Necroptosis: a specialized pathway of programmed necrosis. Cell 135: 1161-1163.
27. Pakhomova ON, Gregory BW, Khorokhorina VA, Bowman AM, Xiao S, et al. (2011) Electroporation-induced electrosensitization. PLoS One 6: e17100.
28. Bowman AM, Nesin OM, Pakhomova ON, Pakhomov AG, (2010) Analysis of plasma membrane integrity by fluorescent detection of Tl(+) uptake. J Membr Biol 236: 15-26.
29. André FM, Rassokhin RA, Bowman AM, Pakhomov AG, (2010) Gadolinium blocks membrane permeabilization induced by nanosecond electric pulses and reduces cell death. Bioelectrochemistry 79: 95-100.
30. De Stefani D, Raffaello A, Teardo E, Szabò I, Rizzuto R, (2011) A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476: 336-40.
31. Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, et al. (2011) Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476: 341-345.
32. Grimm S, (2012) The ER-mitochondria interface: the social network of cell death. Biochim Biophys Acta 1823: 327-334.
33. Nicotera P, Orrenius S, (1998) The role of calcium in apoptosis. Cell Calcium 23: 173-80.
34. Eguchi Y, Shimizu S, Tsujimoto Y, (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57: 1835-1840.
35. Weaver JC, (2003) Electroporation of biological membranes from multicellular to nano scales. IEEE Trans Dielect Elect Insulation 10: 754-768.
36. Zhivotovsky B, Orrenius S, (2011) Calcium and cell death mechanisms: a perspective from the cell death community. Cell Calcium 50: 211-221.
37. Long G, Shires P, Plescia D, Beebe SJ, Kolb JF, et al. (2011) Targeted tissue ablation with nanosecond pulses. IEEE Trans on Biomed Eng 99: 1-7.