Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines

Journal of Ethnopharmacology

Volumn 145, Issue 1, 2013, Pages 146-151

  Chang, Jung San ^a,b   Wang, Kuo Chih ^a   Yeh, Chia Feng ^a   Shieh, Den En ^c   Chiang, Lien Chai ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAJEN UNIVERSITY   (Taiwan)

Author keywords

Plaque assay; Respiratory syncytial virus; Respiratory tract infection; Ribavirin

Indexed keywords

BETA INTERFERON; GINGER EXTRACT;

ANTIVIRAL ACTIVITY; ARTICLE; BOVINE RESPIRATORY SYNCYTIAL VIRUS INFECTION; CELL LINE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; RESPIRATORY TRACT MUCOSA; VIRUS ATTACHMENT;

ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GINGER; HUMANS; INTERFERON-BETA; MICROBIAL SENSITIVITY TESTS; PLANT EXTRACTS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RESPIRATORY SYSTEM; TUMOR NECROSIS FACTOR-ALPHA; VIRAL PLAQUE ASSAY; WATER;

HUMAN RESPIRATORY SYNCYTIAL VIRUS; HYDRANGEA RINGSPOT VIRUS; RESPIRATORY SYNCYTIAL VIRUS; ZINGIBER OFFICINALE;

EID: 84871347325     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.043     Document Type: Article

References (13)

1. B.H. Ali, G. Blunden, M.O. Tanira, and A. Nemmar Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research Food and Chemical Toxicology 46 2008 409 420
2. J.S. Chang, K.C. Wang, D.E. Shieh, F.F. Hsu, and L.C. Chiang Ge-Gen-Tang has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines Journal of Ethnopharmacology 139 2012 305 310
3. L.C. Chiang, W. Chiang, M.Y. Chang, L.T. Ng, and C.C. Lin Antiviral activity of Plantago major extracts and related compounds in vitro Antiviral Research 55 2002 53 62
4. S. Chrubasik, M.H. Pittler, and B.D. Roufogalis Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles Phytomedicine 12 2005 684 701
5. C.V. Denyer, P. Jackson, D.M. Loakes, M.R. Ellis, and D.A. Young Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale) Journal of Natural Products 57 1994 658 662
6. R. Dolin Common viral respiratory infections D.L. Longo, A.S. Fauci, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo, Harrison's Principles of Internal Medicine 1 2012 McGraw-Hill New York 1485 1492
7. A.R. Falsey, P.A. Hennessey, M.A. Formica, C. Cox, and E.E. Walsh Respiratory syncytial virus infection in elderly and high-risk adults New England Journal of Medicine 352 2005 1749 1759
8. S.D. Jolad, R.C. Lantz, G.J. Chen, R.B. Bates, and B.N. Timmermann Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production Phytochemistry 66 2005 1614 1635
9. 2 production Phytochemistry 65 2004 1937 1954
10. C. Koch, J. Reichling, J. Schneele, and P. Schnitzler Inhibitory effect of essential oils against herpes simplex virus type 2 Phytomedicine 15 2008 71 78
11. P. Schnitzler, C. Koch, and J. Reichling Susceptibility of drug-resistant clinical herpes simplex virus type 1 strains to essential oils of ginger, thyme, hyssop, and sandalwood Antimicrobial Agents and Chemotherapy 51 2007 1859 1862
12. K. Sookkongwaree, M. Geitmann, S. Roengsumran, A. Petsom, and U.H. Danielson Inhibition of viral proteases by Zingiberaceae extracts and flavones isolated from Kaempferia parviflora Pharmazie 61 2006 717 721
13. K.C. Wang, J.S. Chang, L.C. Chiang, and C.C. Lin Sheng-Ma-Ge-Gen-Tang (Shomakakkon-to) inhibited cytopathic effect of human respiratory syncytial virus in cell lines of human respiratory tract Journal of Ethnopharmacology 135 2011 538 544