-
1
-
-
3042845655
-
PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates
-
DOI 10.1038/nature02677
-
Lu, X., Borchers, A. G., Jolicoeur, C., Rayburn, H., Baker, J. C., and Tessier-Lavigne, M. (2004) PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 430, 93-98 (Pubitemid 38915231)
-
(2004)
Nature
, vol.430
, Issue.6995
, pp. 93-98
-
-
Lu, X.1
Borchers, A.G.M.2
Jolicoeur, C.3
Rayburn, H.4
Baker, J.C.5
Tessier-Lavigne, M.6
-
2
-
-
69549098206
-
PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation
-
Yen, W. W., Williams, M., Periasamy, A., Conaway, M., Burdsal, C., Keller, R., Lu, X., and Sutherland, A. (2009) PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation. Development 136, 2039-2048
-
(2009)
Development
, vol.136
, pp. 2039-2048
-
-
Yen, W.W.1
Williams, M.2
Periasamy, A.3
Conaway, M.4
Burdsal, C.5
Keller, R.6
Lu, X.7
Sutherland, A.8
-
3
-
-
78650905901
-
Protein-tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling
-
Puppo, F., Thomé, V., Lhoumeau, A. C., Cibois, M., Gangar, A., Lembo, F., Belotti, E., Marchetto, S., Lécine, P., Prébet, T., Sebbagh, M., Shin, W. S., Lee, S. T., Kodjabachian, L., and Borg, J. P. (2011) Protein-tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling. EMBO Rep. 12, 43-49
-
(2011)
EMBO Rep.
, vol.12
, pp. 43-49
-
-
Puppo, F.1
Thomé, V.2
Lhoumeau, A.C.3
Cibois, M.4
Gangar, A.5
Lembo, F.6
Belotti, E.7
Marchetto, S.8
Lécine, P.9
Prébet, T.10
Sebbagh, M.11
Shin, W.S.12
Lee, S.T.13
Kodjabachian, L.14
Borg, J.P.15
-
4
-
-
0034782822
-
The transmembrane protein off-track associates with plexins and functions downstream of semaphorin signaling during axon guidance
-
DOI 10.1016/S0896-6273(01)00446-9
-
Winberg, M. L., Tamagnone, L., Bai, J., Comoglio, P. M., Montell, D., and Goodman, C. S. (2001) The transmembrane protein off-track associates with Plexins and functions downstream of Semaphorin signaling during axon guidance. Neuron 32, 53-62 (Pubitemid 32995889)
-
(2001)
Neuron
, vol.32
, Issue.1
, pp. 53-62
-
-
Winberg, M.L.1
Tamagnone, L.2
Bai, J.3
Comoglio, P.M.4
Montell, D.5
Goodman, C.S.6
-
5
-
-
80052768750
-
PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling
-
Peradziryi, H., Kaplan, N. A., Podleschny, M., Liu, X., Wehner, P., Borchers, A., and Tolwinski, N. S. (2011) PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling. EMBO J. 30, 3729-3740
-
(2011)
EMBO J.
, vol.30
, pp. 3729-3740
-
-
Peradziryi, H.1
Kaplan, N.A.2
Podleschny, M.3
Liu, X.4
Wehner, P.5
Borchers, A.6
Tolwinski, N.S.7
-
6
-
-
0034783983
-
Plexin signaling via Off-track and Rho family GTPases
-
DOI 10.1016/S0896-6273(01)00459-7
-
Whitford, K. L., and Ghosh, A. (2001) Plexin signaling via off-track and rho family GTPases. Neuron 32, 1-3 (Pubitemid 32995882)
-
(2001)
Neuron
, vol.32
, Issue.1
, pp. 1-3
-
-
Whitford, K.L.1
Ghosh, A.2
-
7
-
-
10344247099
-
Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling
-
DOI 10.1038/ncb1193
-
Toyofuku, T., Zhang, H., Kumanogoh, A., Takegahara, N., Yabuki, M., Harada, K., Hori, M., and Kikutani, H. (2004) Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling. Nat. Cell Biol. 6, 1204-1211 (Pubitemid 39625119)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.12
, pp. 1204-1211
-
-
Toyofuku, T.1
Zhang, H.2
Kumanogoh, A.3
Takegahara, N.4
Yabuki, M.5
Harada, K.6
Hori, M.7
Kikutani, H.8
-
8
-
-
60849130746
-
PTK7 recruits dsh to regulate neural crest migration
-
Shnitsar, I., and Borchers, A. (2008) PTK7 recruits dsh to regulate neural crest migration. Development 135, 4015-4024
-
(2008)
Development
, vol.135
, pp. 4015-4024
-
-
Shnitsar, I.1
Borchers, A.2
-
9
-
-
79955129269
-
RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure
-
Wehner, P., Shnitsar, I., Urlaub, H., and Borchers, A. (2011) RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure. Development 138, 1321-1327
-
(2011)
Development
, vol.138
, pp. 1321-1327
-
-
Wehner, P.1
Shnitsar, I.2
Urlaub, H.3
Borchers, A.4
-
10
-
-
79954542163
-
PTK7. A cell polarity receptor with multiple facets
-
Lhoumeau, A. C., Puppo, F., Prébet, T., Kodjabachian, L., and Borg, J. P. (2011) PTK7. A cell polarity receptor with multiple facets. Cell Cycle 10, 1233-1236
-
(2011)
Cell Cycle
, vol.10
, pp. 1233-1236
-
-
Lhoumeau, A.C.1
Puppo, F.2
Prébet, T.3
Kodjabachian, L.4
Borg, J.P.5
-
11
-
-
0037069745
-
Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNA
-
DOI 10.1016/S0167-4781(02)00536-5, PII S0167478102005365
-
Jung, J. W., Ji, A. R., Lee, J., Kim, U. J., and Lee, S. T. (2002) Organization of the human PTK7 gene encoding a receptor protein-tyrosine kinase-like molecule and alternative splicing of its mRNA. Biochim. Biophys. Acta 1579, 153-163 (Pubitemid 35341437)
-
(2002)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1579
, Issue.2-3
, pp. 153-163
-
-
Jung, J.-W.1
Ji, A.-R.2
Lee, J.3
Kim, U.-J.4
Lee, S.-T.5
-
12
-
-
0028880074
-
Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family
-
Mossie, K., Jallal, B., Alves, F., Sures, I., Plowman, G. D., and Ullrich, A. (1995) Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family. Oncogene 11, 2179-2184
-
(1995)
Oncogene
, vol.11
, pp. 2179-2184
-
-
Mossie, K.1
Jallal, B.2
Alves, F.3
Sures, I.4
Plowman, G.D.5
Ullrich, A.6
-
13
-
-
12844276658
-
Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization
-
DOI 10.1002/gcc.20136
-
Gorringe, K. L., Boussioutas, A., and Bowtell, D. D. (2005) Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization. Genes Chromosomes Cancer 42, 247-259 (Pubitemid 40171189)
-
(2005)
Genes Chromosomes and Cancer
, vol.42
, Issue.3
, pp. 247-259
-
-
Gorringe, K.L.1
Boussioutas, A.2
Bowtell, D.D.L.3
-
14
-
-
1542608359
-
Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction
-
DOI 10.1200/JCO.2004.04.109
-
Endoh, H., Tomida, S., Yatabe, Y., Konishi, H., Osada, H., Tajima, K., Kuwano, H., Takahashi, T., and Mitsudomi, T. (2004) Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction. J. Clin. Oncol. 22, 811-819 (Pubitemid 41103592)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 811-819
-
-
Endoh, H.1
Tomida, S.2
Yatabe, Y.3
Konishi, H.4
Osada, H.5
Tajima, K.6
Kuwano, H.7
Takahashi, T.8
Mitsudomi, T.9
-
15
-
-
12144289595
-
High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets
-
DOI 10.1158/1078-0432.CCR-0954-03
-
Müller-Tidow, C., Schwäble, J., Steffen, B., Tidow, N., Brandt, B., Becker, K., Schulze-Bahr, E., Halfter, H., Vogt, U., Metzger, R., Schneider, P. M., Büchner, T., Brandts, C., Berdel, W. E., and Serve, H. (2004) High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets. Clin. Cancer Res. 10, 1241-1249 (Pubitemid 38365213)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.4
, pp. 1241-1249
-
-
Muller-Tidow, C.1
Schwable, J.2
Steffen, B.3
Tidow, N.4
Brandt, B.5
Becker, K.6
Schulze-Bahr, E.7
Halfter, H.8
Vogt, U.9
Metzger, R.10
Schneider, P.M.11
Buchner, T.12
Brandts, C.13
Berdel, W.E.14
Serve, H.15
-
16
-
-
0030970669
-
Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma
-
DOI 10.1002/(SICI)1097-0215(19970611)71:6<1061::AID-IJC24>3.0.CO;2- F
-
Easty, D. J., Mitchell, P. J., Patel, K., Flørenes, V. A., Spritz, R. A., and Bennett, D. C. (1997) Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma. Int. J. Cancer 71, 1061-1065 (Pubitemid 27252891)
-
(1997)
International Journal of Cancer
, vol.71
, Issue.6
, pp. 1061-1065
-
-
Easty, D.J.1
Mitchell, P.J.2
Patel, K.3
FlOOrenes, V.A.4
Spritz, R.A.5
Bennett, D.C.6
-
17
-
-
79955495142
-
Undetectable and decreased expression of KIAA1949 (Phostensin) encoded on chromosome 6p21.33 in human breast cancers revealed by transcriptome analysis
-
Su, Y. A., Yang, J., Tao, L., Nguyen, H., and He, P. (2010) Undetectable and decreased expression of KIAA1949 (Phostensin) encoded on chromosome 6p21.33 in human breast cancers revealed by transcriptome analysis. J. Cancer 1, 38-50
-
(2010)
J. Cancer
, vol.1
, pp. 38-50
-
-
Su, Y.A.1
Yang, J.2
Tao, L.3
Nguyen, H.4
He, P.5
-
18
-
-
0035159881
-
Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysis
-
Piao, Z., Lee, K. S., Kim, H., Perucho, M., and Malkhosyan, S. (2001) Identification of novel deletion regions on chromosome arms 2q and 6p in breast carcinomas by amplotype analysis. Genes Chromosomes Cancer 30, 113-122 (Pubitemid 32044592)
-
(2001)
Genes Chromosomes and Cancer
, vol.30
, Issue.2
, pp. 113-122
-
-
Piao, Z.1
Lee, K.S.2
Kim, H.3
Perucho, M.4
Malkhosyan, T.S.5
-
19
-
-
0034019515
-
An isochromosome 6p in a primary meningeal malignant melanoma
-
Baudrier-Régnier, A., Bodenant, C., Proust, F., Delangre, T., Hemet, J., and Laquerrière, A. (2000) An isochromosome 6p in a primary meningeal malignant melanoma. Cancer Genet Cytogenet 119, 80-82
-
(2000)
Cancer Genet Cytogenet
, vol.119
, pp. 80-82
-
-
Baudrier-Régnier, A.1
Bodenant, C.2
Proust, F.3
Delangre, T.4
Hemet, J.5
Laquerrière, A.6
-
20
-
-
63149117373
-
Role of ADAMs in cancer formation and progression
-
Duffy, M. J., McKiernan, E., O'Donovan, N., and McGowan, P. M. (2009) Role of ADAMs in cancer formation and progression. Clin. Cancer Res. 15, 1140-1144
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1140-1144
-
-
Duffy, M.J.1
McKiernan, E.2
O'Donovan, N.3
McGowan, P.M.4
-
21
-
-
0028969678
-
The metzincins-topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc peptidases
-
Stocker, W., Grams, F., Baumann, U., Reinemer, P., Gomis-Ruth, F. X., McKay, D. B., and Bode, W. (1995) The metzincins-topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc peptidases. Protein Sci. 4, 823-840
-
(1995)
Protein Sci.
, vol.4
, pp. 823-840
-
-
Stocker, W.1
Grams, F.2
Baumann, U.3
Reinemer, P.4
Gomis-Ruth, F.X.5
McKay, D.B.6
Bode, W.7
-
22
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad, M., and Werb, Z. (2002) New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2, 161-174 (Pubitemid 37328786)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.3
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
23
-
-
28444454893
-
MT1-MMP: A potent modifier of pericellular microenvironment
-
DOI 10.1002/jcp.20431
-
Itoh, Y., and Seiki, M. (2006) MT1-MMP. A potent modifier of pericellular microenvironment. J. Cell Physiol. 206, 1-8 (Pubitemid 41740711) ????????????????start here????????????????????
-
(2006)
Journal of Cellular Physiology
, vol.206
, Issue.1
, pp. 1-8
-
-
Itoh, Y.1
Seiki, M.2
-
24
-
-
70349335653
-
Matrix metalloproteinase proteomics. Substrates, targets, and therapy
-
Morrison, C. J., Butler, G. S., Rodríguez, D., and Overall, C. M. (2009) Matrix metalloproteinase proteomics. Substrates, targets, and therapy. Curr. Opin. Cell Biol. 21, 645-653
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 645-653
-
-
Morrison, C.J.1
Butler, G.S.2
Rodríguez, D.3
Overall, C.M.4
-
25
-
-
77149164774
-
Matrix metalloproteinases. What do they not do? New substrates and biological roles identified by murine models and proteomics
-
Rodríguez, D., Morrison, C. J., and Overall, C. M. (2010) Matrix metalloproteinases. What do they not do? New substrates and biological roles identified by murine models and proteomics. Biochim. Biophys. Acta 1803, 39-54
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 39-54
-
-
Rodríguez, D.1
Morrison, C.J.2
Overall, C.M.3
-
26
-
-
33749350351
-
A cancer cell metalloprotease triad regulates the basement membrane transmigration program
-
DOI 10.1101/gad.1451806
-
Hotary, K., Li, X. Y., Allen, E., Stevens, S. L., and Weiss, S. J. (2006) A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes Dev. 20, 2673-2686 (Pubitemid 44498378)
-
(2006)
Genes and Development
, vol.20
, Issue.19
, pp. 2673-2686
-
-
Hotary, K.1
Li, X.-Y.2
Allen, E.3
Stevens, S.L.4
Weiss, S.J.5
-
27
-
-
0038784546
-
Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix
-
DOI 10.1016/S0092-8674(03)00513-0
-
Hotary, K. B., Allen, E. D., Brooks, P. C., Datta, N. S., Long, M. W., and Weiss, S. J. (2003) Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. Cell 114, 33-45 (Pubitemid 36859839)
-
(2003)
Cell
, vol.114
, Issue.1
, pp. 33-45
-
-
Hotary, K.B.1
Allen, E.D.2
Brooks, P.C.3
Datta, N.S.4
Long, M.W.5
Weiss, S.J.6
-
28
-
-
0034641107
-
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3
-
DOI 10.1083/jcb.149.6.1309
-
Hotary, K., Allen, E., Punturieri, A., Yana, I., and Weiss, S. J. (2000) Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J. Cell Biol. 149, 1309-1323 (Pubitemid 30399683)
-
(2000)
Journal of Cell Biology
, vol.149
, Issue.6
, pp. 1309-1323
-
-
Hotary, K.1
Allen, E.2
Punturieri, A.3
Yana, I.4
Weiss, S.J.5
-
29
-
-
9444290419
-
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
-
DOI 10.1083/jcb.200408028
-
Sabeh, F., Ota, I., Holmbeck, K., Birkedal-Hansen, H., Soloway, P., Balbin, M., Lopez-Otin, C., Shapiro, S., Inada, M., Krane, S., Allen, E., Chung, D., and Weiss, S. J. (2004) Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J. Cell Biol. 167, 769-781 (Pubitemid 39565156)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.4
, pp. 769-781
-
-
Sabeh, F.1
Ota, I.2
Holmbeck, K.3
Birkedal-Hansen, H.4
Soloway, P.5
Balbin, M.6
Lopez-Otin, C.7
Shapiro, S.8
Inada, M.9
Krane, S.10
Allen, E.11
Chung, D.12
Weiss, S.J.13
-
30
-
-
0035947675
-
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion
-
Belkin, A. M., Akimov, S. S., Zaritskaya, L. S., Ratnikov, B. I., Deryugina, E. I., and Strongin, A. Y. (2001) Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion. J. Biol. Chem. 276, 18415-18422
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18415-18422
-
-
Belkin, A.M.1
Akimov, S.S.2
Zaritskaya, L.S.3
Ratnikov, B.I.4
Deryugina, E.I.5
Strongin, A.Y.6
-
31
-
-
0035947766
-
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration
-
DOI 10.1083/jcb.153.5.893
-
Kajita, M., Itoh, Y., Chiba, T., Mori, H., Okada, A., Kinoh, H., and Seiki, M. (2001) Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J. Cell Biol. 153, 893-904 (Pubitemid 34289231)
-
(2001)
Journal of Cell Biology
, vol.153
, Issue.5
, pp. 893-904
-
-
Kajita, M.1
Itoh, Y.2
Chiba, T.3
Mori, H.4
Okada, A.5
Kinoh, H.6
Seiki, M.7
-
32
-
-
0037155874
-
v subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase
-
v subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase. J. Biol. Chem. 277, 9749-9756
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9749-9756
-
-
Deryugina, E.I.1
Ratnikov, B.I.2
Postnova, T.I.3
Rozanov, D.V.4
Strongin, A.Y.5
-
33
-
-
49249137190
-
Molecular signature of MT1-MMP. Transactivation of the downstream universal gene network in cancer
-
Rozanov, D. V., Savinov, A. Y., Williams, R., Liu, K., Golubkov, V. S., Krajewski, S., and Strongin, A. Y. (2008) Molecular signature of MT1-MMP. Transactivation of the downstream universal gene network in cancer. Cancer Res. 68, 4086-4096
-
(2008)
Cancer Res.
, vol.68
, pp. 4086-4096
-
-
Rozanov, D.V.1
Savinov, A.Y.2
Williams, R.3
Liu, K.4
Golubkov, V.S.5
Krajewski, S.6
Strongin, A.Y.7
-
34
-
-
0038026913
-
Role of pericellular proteolysis by membrane-type 1 matrix metalloproteinase in cancer invasion and angiogenesis
-
DOI 10.1023/A:1023087113214
-
Seiki, M., Koshikawa, N., and Yana, I. (2003) Role of pericellular proteolysis by membrane-type 1 matrix metalloproteinase in cancer invasion and angiogenesis. Cancer Metastasis Rev. 22, 129-143 (Pubitemid 36561053)
-
(2003)
Cancer and Metastasis Reviews
, vol.22
, Issue.2-3
, pp. 129-143
-
-
Seiki, M.1
Koshikawa, N.2
Yana, I.3
-
35
-
-
63349102395
-
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
-
Rowe, R. G., Li, X. Y., Hu, Y., Saunders, T. L., Virtanen, I., Garcia de Herreros, A., Becker, K. F., Ingvarsen, S., Engelholm, L. H., Bommer, G. T., Fearon, E. R., and Weiss, S. J. (2009) Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J. Cell Biol. 184, 399-408
-
(2009)
J. Cell Biol.
, vol.184
, pp. 399-408
-
-
Rowe, R.G.1
Li, X.Y.2
Hu, Y.3
Saunders, T.L.4
Virtanen, I.5
Garcia De Herreros, A.6
Becker, K.F.7
Ingvarsen, S.8
Engelholm, L.H.9
Bommer, G.T.10
Fearon, E.R.11
Weiss, S.J.12
-
36
-
-
44349156127
-
MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease
-
DOI 10.1038/sj.onc.1210982, PII 1210982
-
Szabova, L., Chrysovergis, K., Yamada, S. S., and Holmbeck, K. (2008) MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease. Oncogene 27, 3274-3281 (Pubitemid 351733384)
-
(2008)
Oncogene
, vol.27
, Issue.23
, pp. 3274-3281
-
-
Szabova, L.1
Chrysovergis, K.2
Yamada, S.S.3
Holmbeck, K.4
-
37
-
-
2642572799
-
MT1-MMP. A tethered collagenase
-
Holmbeck, K., Bianco, P., Yamada, S., and Birkedal-Hansen, H. (2004) MT1-MMP. A tethered collagenase. J. Cell Physiol. 200, 11-19
-
(2004)
J. Cell Physiol.
, vol.200
, pp. 11-19
-
-
Holmbeck, K.1
Bianco, P.2
Yamada, S.3
Birkedal-Hansen, H.4
-
38
-
-
2142784516
-
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
-
DOI 10.1016/S0092-8674(00)80064-1
-
Holmbeck, K., Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S. A., Mankani, M., Robey, P. G., Poole, A. R., Pidoux, I., Ward, J. M., and Birkedal-Hansen, H. (1999) MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99, 81-92 (Pubitemid 29468632)
-
(1999)
Cell
, vol.99
, Issue.1
, pp. 81-92
-
-
Holmbeck, K.1
Bianco, P.2
Caterina, J.3
Yamada, S.4
Kromer, M.5
Kuznetsov, S.A.6
Mankani, M.7
Gehron, R.P.8
Poole, A.R.9
Pidoux, I.10
Ward, J.M.11
Birkedal-Hansen, H.12
-
39
-
-
34147105872
-
ADAMs in cancer cell proliferation and progression
-
DOI 10.1111/j.1349-7006.2007.00434.x
-
Mochizuki, S., and Okada, Y. (2007) ADAMs in cancer cell proliferation and progression. Cancer Sci. 98, 621-628 (Pubitemid 46563436)
-
(2007)
Cancer Science
, vol.98
, Issue.5
, pp. 621-628
-
-
Mochizuki, S.1
Okada, Y.2
-
40
-
-
63649128433
-
Regulation of the proteolytic disintegrin metalloproteinases, the "Sheddases."
-
Murphy, G. (2009) Regulation of the proteolytic disintegrin metalloproteinases, the "Sheddases." Semin. Cell Dev. Biol. 20, 138-145
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 138-145
-
-
Murphy, G.1
-
41
-
-
84860641102
-
The ADAMs family of proteases. New biomarkers and therapeutic targets for cancer?
-
Duffy, M. J., Mullooly, M., O'Donovan, N., Sukor, S., Crown, J., Pierce, A., and McGowan, P. M. (2011) The ADAMs family of proteases. New biomarkers and therapeutic targets for cancer? Clin. Proteomics 8, 9
-
(2011)
Clin. Proteomics
, vol.8
, pp. 9
-
-
Duffy, M.J.1
Mullooly, M.2
O'Donovan, N.3
Sukor, S.4
Crown, J.5
Pierce, A.6
McGowan, P.M.7
-
42
-
-
77049113770
-
The tissue inhibitors of metalloproteinases (TIMPs). An ancient family with structural and functional diversity
-
Brew, K., and Nagase, H. (2010) The tissue inhibitors of metalloproteinases (TIMPs). An ancient family with structural and functional diversity. Biochim. Biophys. Acta 1803, 55-71
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 55-71
-
-
Brew, K.1
Nagase, H.2
-
43
-
-
79958014429
-
Potential relation of aberrant proteolysis of human protein-tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects
-
Golubkov, V. S., Aleshin, A. E., and Strongin, A. Y. (2011) Potential relation of aberrant proteolysis of human protein-tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects. J. Biol. Chem. 286, 20970-20976
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20970-20976
-
-
Golubkov, V.S.1
Aleshin, A.E.2
Strongin, A.Y.3
-
44
-
-
78149234115
-
The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase. Implications in cancer and embryogenesis
-
Golubkov, V. S., Chekanov, A. V., Cieplak, P., Aleshin, A. E., Chernov, A. V., Zhu, W., Radichev, I. A., Zhang, D., Dong, P. D., and Strongin, A. Y. (2010) The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase. Implications in cancer and embryogenesis. J. Biol. Chem. 285, 35740-35749
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35740-35749
-
-
Golubkov, V.S.1
Chekanov, A.V.2
Cieplak, P.3
Aleshin, A.E.4
Chernov, A.V.5
Zhu, W.6
Radichev, I.A.7
Zhang, D.8
Dong, P.D.9
Strongin, A.Y.10
-
45
-
-
74049133907
-
Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells
-
Sounni, N. E., Rozanov, D. V., Remacle, A. G., Golubkov, V. S., Noel, A., and Strongin, A. Y. (2010) Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells. Int. J. Cancer 126, 1067-1078
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1067-1078
-
-
Sounni, N.E.1
Rozanov, D.V.2
Remacle, A.G.3
Golubkov, V.S.4
Noel, A.5
Strongin, A.Y.6
-
46
-
-
21644469164
-
Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability
-
DOI 10.1074/jbc.M502779200
-
Golubkov, V. S., Boyd, S., Savinov, A. Y., Chekanov, A. V., Osterman, A. L., Remacle, A., Rozanov, D. V., Doxsey, S. J., and Strongin, A. Y. (2005) Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability. J. Biol. Chem. 280, 25079-25086 (Pubitemid 40934599)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 25079-25086
-
-
Golubkov, V.S.1
Boyd, S.2
Savinov, A.Y.3
Chekanov, A.V.4
Osterman, A.L.5
Remacle, A.6
Rozanov, D.V.7
Doxsey, S.J.8
Strongin, A.Y.9
-
47
-
-
33751288188
-
Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells
-
DOI 10.1158/0008-5472.CAN-06-2997
-
Golubkov, V. S., Chekanov, A. V., Savinov, A. Y., Rozanov, D. V., Golubkova, N. V., and Strongin, A. Y. (2006) Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells. Cancer Res. 66, 10460-10465 (Pubitemid 44799767)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10460-10465
-
-
Golubkov, V.S.1
Chekanov, A.V.2
Savinov, A.Y.3
Rozanov, D.V.4
Golubkova, N.V.5
Strongin, A.Y.6
-
48
-
-
79952220937
-
PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways
-
Kveiborg, M., Instrell, R., Rowlands, C., Howell, M., and Parker, P. J. (2011) PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways. PLoS One 6, e17168
-
(2011)
PLoS One
, vol.6
-
-
Kveiborg, M.1
Instrell, R.2
Rowlands, C.3
Howell, M.4
Parker, P.J.5
-
49
-
-
65549120390
-
ADAM-10-mediated N-cadherin cleavage is protein kinase Cα dependent and promotes glioblastoma cell migration
-
Kohutek, Z. A., diPierro, C. G., Redpath, G. T., and Hussaini, I. M. (2009) ADAM-10-mediated N-cadherin cleavage is protein kinase Cα dependent and promotes glioblastoma cell migration. J. Neurosci. 29, 4605-4615
-
(2009)
J. Neurosci.
, vol.29
, pp. 4605-4615
-
-
Kohutek, Z.A.1
DiPierro, C.G.2
Redpath, G.T.3
Hussaini, I.M.4
-
50
-
-
10944243611
-
Regulation of ADAM12 cell-surface expression by protein kinase C ε
-
DOI 10.1074/jbc.M403753200
-
Sundberg, C., Thodeti, C. K., Kveiborg, M., Larsson, C., Parker, P., Albrechtsen, R., and Wewer, U. M. (2004) Regulation of ADAM12 cell-surface expression by protein kinase Cε. J. Biol. Chem. 279, 51601-51611 (Pubitemid 40017911)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.49
, pp. 51601-51611
-
-
Sundberg, C.1
Thodeti, C.K.2
Kveiborg, M.3
Larsson, C.4
Parker, P.5
Albrechtsen, R.6
Wewer, U.M.7
-
51
-
-
0242413280
-
Regulated Cell Surface Pro-EGF Ectodomain Shedding Is a Zinc Metalloprotease-dependent Process
-
DOI 10.1074/jbc.M307745200
-
Le Gall, S. M., Auger, R., Dreux, C., and Mauduit, P. (2003) Regulated cell surface pro-EGF ectodomain shedding is a zinc metalloprotease-dependent process. J. Biol. Chem. 278, 45255-45268 (Pubitemid 37432660)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45255-45268
-
-
Le, G.S.M.1
Auger, R.2
Dreux, C.3
Mauduit, P.4
-
52
-
-
78951481235
-
Role of Notch and its oncogenic signaling crosstalk in breast cancer
-
Guo, S., Liu, M., and Gonzalez-Perez, R. R. (2011) Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim. Biophys. Acta 1815, 197-213
-
(2011)
Biochim. Biophys. Acta
, vol.1815
, pp. 197-213
-
-
Guo, S.1
Liu, M.2
Gonzalez-Perez, R.R.3
-
53
-
-
0032815883
-
Adamalysins. A family of metzincins including TNF-α converting enzyme (TACE)
-
DOI 10.1111/j.1749-6632.1999.tb07701.x
-
Killar, L., White, J., Black, R., and Peschon, J. (1999) Adamalysins. A family of metzincins including TNF-α converting enzyme (TACE). Ann. N.Y. Acad. Sci. 878, 442-452 (Pubitemid 29353587)
-
(1999)
Annals of the New York Academy of Sciences
, vol.878
, pp. 442-452
-
-
Killar, L.1
White, J.2
Black, R.3
Peschon, J.4
-
54
-
-
79953174990
-
Membrane proteases and tetraspanins
-
Yañez-Mó, M., Sánchez-Madrid, F., and Cabañas, C. (2011) Membrane proteases and tetraspanins. Biochem. Soc. Trans. 39, 541-546
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 541-546
-
-
Yañez-Mó, M.1
Sánchez-Madrid, F.2
Cabañas, C.3
-
55
-
-
79955663580
-
Regulated intramembrane proteolysis. Lessons from amyloid precursor protein processing
-
Lichtenthaler, S. F., Haass, C., and Steiner, H. (2011) Regulated intramembrane proteolysis. Lessons from amyloid precursor protein processing. J. Neurochem. 117, 779-796
-
(2011)
J. Neurochem.
, vol.117
, pp. 779-796
-
-
Lichtenthaler, S.F.1
Haass, C.2
Steiner, H.3
-
56
-
-
84855515743
-
Ectdomain shedding and regulated intracellular proteolysis in the central nervous system
-
Montes de Oca-B., P. (2010) Ectdomain shedding and regulated intracellular proteolysis in the central nervous system. Cent. Nerv. Syst. Agents Med. Chem. 10, 337-359
-
(2010)
Cent. Nerv. Syst. Agents Med. Chem.
, vol.10
, pp. 337-359
-
-
Montes De Oca-B, P.1
-
57
-
-
46449089731
-
ADAM proteases. Ligand processing and modulation of the Notch pathway
-
Zolkiewska, A. (2008) ADAM proteases. Ligand processing and modulation of the Notch pathway. Cell Mol. Life Sci. 65, 2056-2068
-
(2008)
Cell Mol. Life Sci.
, vol.65
, pp. 2056-2068
-
-
Zolkiewska, A.1
-
58
-
-
84864106172
-
The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells
-
Na, H. W., Shin, W. S., Ludwig, A., and Lee, S. T. (2012) The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells. J. Biol. Chem. 287, 25001-25009
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 25001-25009
-
-
Na, H.W.1
Shin, W.S.2
Ludwig, A.3
Lee, S.T.4
-
59
-
-
0032502719
-
Lactacystin, proteasome function, and cell fate
-
DOI 10.1074/jbc.273.15.8545
-
Fenteany, G., and Schreiber, S. L. (1998) Lactacystin, proteasome function, and cell fate. J. Biol. Chem. 273, 8545-8548 (Pubitemid 28176125)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.15
, pp. 8545-8548
-
-
Fenteany, G.1
Schreiber, S.L.2
-
60
-
-
0034685834
-
The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3
-
DOI 10.1016/S0014-5793(00)01528-3, PII S0014579300015283
-
Amour, A., Knight, C. G., Webster, A., Slocombe, P. M., Stephens, P. E., Knäuper, V., Docherty, A. J., and Murphy, G. (2000) The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3. FEBS Lett. 473, 275-279 (Pubitemid 30249139)
-
(2000)
FEBS Letters
, vol.473
, Issue.3
, pp. 275-279
-
-
Amour, A.1
Knight, C.G.2
Webster, A.3
Slocombe, P.M.4
Stephens, P.E.5
Knauper, V.6
Docherty, A.J.P.7
Murphy, G.8
-
61
-
-
10744221757
-
Differential Inhibition of Membrane Type 3 (MT3)-Matrix Metalloproteinase (MMP) and MT1-MMP by Tissue Inhibitor of Metalloproteinase (TIMP)-2 and TIMP-3 Regulates Pro-MMP-2 Activation
-
DOI 10.1074/jbc.M308708200
-
Zhao, H., Bernardo, M. M., Osenkowski, P., Sohail, A., Pei, D., Nagase, H., Kashiwagi, M., Soloway, P. D., DeClerck, Y. A., and Fridman, R. (2004) Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation. J. Biol. Chem. 279, 8592-8601 (Pubitemid 38295913)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 8592-8601
-
-
Zhao, H.1
Bernardo, M.M.2
Osenkowski, P.3
Sohail, A.4
Pei, D.5
Nagase, H.6
Kashiwagi, M.7
Soloway, P.D.8
DeClerck, Y.A.9
Fridman, R.10
-
62
-
-
79953126754
-
The role of ADAMTSs in arthritis
-
Lin, E. A., and Liu, C. J. (2010) The role of ADAMTSs in arthritis. Protein Cell 1, 33-47
-
(2010)
Protein Cell
, vol.1
, pp. 33-47
-
-
Lin, E.A.1
Liu, C.J.2
-
63
-
-
77956644315
-
Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5. Biological and structural implications
-
Lim, N. H., Kashiwagi, M., Visse, R., Jones, J., Enghild, J. J., Brew, K., and Nagase, H. (2010) Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5. Biological and structural implications. Biochem. J. 431, 113-122
-
(2010)
Biochem. J.
, vol.431
, pp. 113-122
-
-
Lim, N.H.1
Kashiwagi, M.2
Visse, R.3
Jones, J.4
Enghild, J.J.5
Brew, K.6
Nagase, H.7
-
64
-
-
70449707207
-
ADAM17 co-purifies with TIMP-3 and modulates endothelial invasion responses in three-dimensional collagen matrices
-
Kwak, H. I., Mendoza, E. A., and Bayless, K. J. (2009) ADAM17 co-purifies with TIMP-3 and modulates endothelial invasion responses in three-dimensional collagen matrices. Matrix Biol. 28, 470-479
-
(2009)
Matrix Biol.
, vol.28
, pp. 470-479
-
-
Kwak, H.I.1
Mendoza, E.A.2
Bayless, K.J.3
-
65
-
-
21644449866
-
ADAMTS proteinases: A multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis
-
DOI 10.1186/ar1783
-
Jones, G. C., and Riley, G. P. (2005) ADAMTS proteinases. A multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis. Arthritis Res. Ther. 7, 160-169 (Pubitemid 40936607)
-
(2005)
Arthritis Research and Therapy
, vol.7
, Issue.4
, pp. 160-169
-
-
Jones, G.C.1
Riley, G.P.2
-
66
-
-
18444388856
-
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs
-
DOI 10.1016/S0014-5793(02)03047-8, PII S0014579302030478
-
Amour, A., Knight, C. G., English, W. R., Webster, A., Slocombe, P. M., Knäuper, V., Docherty, A. J., Becherer, J. D., Blobel, C. P., and Murphy, G. (2002) The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett. 524, 154-158 (Pubitemid 34804852)
-
(2002)
FEBS Letters
, vol.524
, Issue.1-3
, pp. 154-158
-
-
Amour, A.1
Knight, C.G.2
English, W.R.3
Webster, A.4
Slocombe, P.M.5
Knauper, V.6
Docherty, A.J.P.7
Becherer, J.D.8
Blobel, C.P.9
Murphy, G.10
-
67
-
-
0035328844
-
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase a via efficient inhibition of membrane type 1-matrix metalloproteinase
-
Bigg, H. F., Morrison, C. J., Butler, G. S., Bogoyevitch, M. A., Wang, Z., Soloway, P. D., and Overall, C. M. (2001) Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase. Cancer Res. 61, 3610-3618 (Pubitemid 32694971)
-
(2001)
Cancer Research
, vol.61
, Issue.9
, pp. 3610-3618
-
-
Bigg, H.F.1
Morrison, C.J.2
Butler, G.S.3
Bogoyevitch, M.A.4
Wang, Z.5
Soloway, P.D.6
Overall, C.M.7
-
68
-
-
18144384702
-
Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: Fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-α-converting enzyme
-
DOI 10.1074/jbc.M500897200
-
Lee, M. H., Rapti, M., and Murphy, G. (2005) Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting. Fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-α- converting enzyme. J. Biol. Chem. 280, 15967-15975 (Pubitemid 40616720)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 15967-15975
-
-
Lee, M.-H.1
Rapti, M.2
Murphy, G.3
-
69
-
-
33745791118
-
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer
-
DOI 10.1016/j.ccr.2006.05.024, PII S1535610806001802
-
Zhou, B. B., Peyton, M., He, B., Liu, C., Girard, L., Caudler, E., Lo, Y., Baribaud, F., Mikami, I., Reguart, N., Yang, G., Li, Y., Yao, W., Vaddi, K., Gazdar, A. F., Friedman, S. M., Jablons, D. M., Newton, R. C., Fridman, J. S., Minna, J. D., and Scherle, P. A. (2006) Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell 10, 39-50 (Pubitemid 44018087)
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 39-50
-
-
Zhou, B.-B.S.1
Peyton, M.2
He, B.3
Liu, C.4
Girard, L.5
Caudler, E.6
Lo, Y.7
Baribaud, F.8
Mikami, I.9
Reguart, N.10
Yang, G.11
Li, Y.12
Yao, W.13
Vaddi, K.14
Gazdar, A.F.15
Friedman, S.M.16
Jablons, D.M.17
Newton, R.C.18
Fridman, J.S.19
Minna, J.D.20
Scherle, P.A.21
more..
-
70
-
-
34250167944
-
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer
-
DOI 10.1158/1078-0432.CCR-06-2116
-
Fridman, J. S., Caulder, E., Hansbury, M., Liu, X., Yang, G., Wang, Q., Lo, Y., Zhou, B. B., Pan, M., Thomas, S. M., Grandis, J. R., Zhuo, J., Yao, W., Newton, R. C., Friedman, S. M., Scherle, P. A., and Vaddi, K. (2007) Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer. Clin. Cancer Res. 13, 1892-1902 (Pubitemid 46952960)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1892-1902
-
-
Fridman, J.S.1
Caulder, E.2
Hansbury, M.3
Liu, X.4
Yang, G.5
Wang, Q.6
Lo, Y.7
Zhou, B.-B.8
Pan, M.9
Thomas, S.M.10
Grandis, J.R.11
Zhuo, J.12
Yao, W.13
Newton, R.C.14
Friedman, S.M.15
Scherle, P.A.16
Vaddi, K.17
|