Spectrum of physiological and pathological cardiac and pericardial uptake of FDG in oncology PET-CT

Clinical Radiology

Volumn 68, Issue 1, 2013, Pages

  Lobert, P ^a   Brown, R K J ^a   Dvorak, R A ^a   Corbett, J R ^a   Kazerooni, E A ^a   Wong, K K ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

CANCER STAGING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC IMAGING; DRUG UPTAKE; FATTY ACID METABOLISM; GLUCOSE UTILIZATION; HEART MUSCLE; HUMAN; LYMPHOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PERICARDIUM; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; SOLID TUMOR; TREATMENT RESPONSE;

ADIPOSE TISSUE, BROWN; ARTIFACTS; CARDIOMYOPATHIES; FLUORODEOXYGLUCOSE F18; HEART ATRIA; HEART DISEASES; HEART VENTRICLES; HUMANS; LEUKEMIA; LYMPHOMA; MYOCARDIUM; ORGAN SPECIFICITY; PAPILLARY MUSCLES; PERICARDITIS; PERICARDIUM; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; SARCOIDOSIS;

EID: 84871318671     PISSN: 00099260     EISSN: 1365229X     Source Type: Journal    
DOI: 10.1016/j.crad.2012.09.007     Document Type: Review

References (93)

1. G. Del Rocio Estrada-Sanchez, J. Altamirano-Ley, and F.J. Ochoa-Carrillo Normal variants and frequent pitfalls with (18)FDG PET/CT study Cir Cir 75 2007 491 497
2. K. Fukuchi, H. Ohta, and K. Matsumura Benign variations and incidental abnormalities of myocardial FDG uptake in the fasting state as encountered during routine oncology positron emission tomography studies Br J Radiol 80 2007 3 11
3. W. Makis, A. Ciarallo, and M. Hickeson Spectrum of malignant pleural and pericardial disease on FDG PET/CT AJR Am J Roentgenol 198 2012 678 685
4. 18F FDG uptake at oncologic PET/CT RadioGraphics 31 2011 1287 1305
5. F.M. Bengel, T. Higuchi, and M.S. Javadi Cardiac positron emission tomography J Am Coll Cardiol 54 2009 1 15
6. N. Ghosh, O.E. Rimoldi, and R.S. Beanlands Assessment of myocardial ischaemia and viability: role of positron emission tomography Eur Heart J 31 2010 2984 2995
7. L. Lalonde, M.C. Ziadi, and R. Beanlands Cardiac positron emission tomography: current clinical practice Cardiol Clin 27 2009 237 255
8. G.D. Lopaschuk, and W.C. Stanley Glucose metabolism in the ischemic heart Circulation 95 1997 313 315
9. 18F-FDG PET/CT J Nucl Med 48 2007 1662 1669
10. R.J. Gropler, B.A. Siegel, and K.J. Lee Nonuniformity in myocardial accumulation of fluorine-18-fluorodeoxyglucose in normal fasted humans J Nucl Med 31 1990 1749 1756
11. 18F-FDG uptake during PET: a randomized controlled trial J Nucl Cardiol 17 2010 286 291
12. 18F-FDG uptake by preparing patients with a high-fat, low-carbohydrate diet AJR Am J Roentgenol 190 2008 W151 W156
13. M. Yamanouchi, K. Yoshida, and H. Niwayama Effect of the duration of fasting on myocardial fluorine-18-fluorodeoxyglucose positron emission tomography images in normal males Jpn Circ J 60 1996 319 327
14. M. de Groot, A.P. Meeuwis, and P.J. Kok Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut Eur J Nucl Med Mol Imaging 32 2005 98 101
15. T. Kaneta, T. Hakamatsuka, and K. Takanami Evaluation of the relationship between physiological FDG uptake in the heart and age, blood glucose level, fasting period, and hospitalization Ann Nucl Med 20 2006 203 208
16. A.P. Viljanen, A. Karmi, and R. Borra Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults Am J Cardiol 103 2009 1721 1726
17. 18F-FDG PET-CT in the detection of cardiac sarcoidosis J Nucl Cardiol 16 2009 801 810
18. 18F-Fluoro-2- deoxyglucose positron emission tomography in cardiac sarcoidosis Eur J Nucl Med Mol Imaging 38 9 2011 1773 1783
19. 18F-FDG PET in identification of cardiac sarcoidosis J Nucl Med 45 2004 1989 1998
20. H. Ohira, I. Tsujino, and T. Sato Early detection of cardiac sarcoid lesions with (18)F-fluoro-2-deoxyglucose positron emission tomography Intern Med 50 2011 1207 1209
21. J.A. Fallavollita, A.J. Luisi Jr., and E. Yun An abbreviated hyperinsulinemic-euglycemic clamp results in similar myocardial glucose utilization in both diabetic and non-diabetic patients with ischemic cardiomyopathy J Nucl Cardiol 17 2010 637 645
22. 18F-fluorodeoxyglucose gated PET cardiac imaging: comparative results Nucl Med Commun 19 1998 867 874
23. G.D. Vitale, R.A. deKemp, and T.D. Ruddy Myocardial glucose utilization and optimization of (18)F-FDG PET imaging in patients with non-insulin-dependent diabetes mellitus, coronary artery disease, and left ventricular dysfunction J Nucl Med 42 2001 1730 1736
24. L. Le Meunier, R. Maass-Moreno, and J.A. Carrasquillo PET/CT imaging: effect of respiratory motion on apparent myocardial uptake J Nucl Cardiol 13 2006 821 830
25. 18F]fluoro-d-glucose myocardial uptake: effect of respiratory motion Mol Imaging Biol 5 2003 57 64
26. A. Bass, M. Stejskalova, and B. Ostadal Differences between atrial and ventricular energy-supplying enzymes in five mammalian species Physiol Res 42 1993 1 6
27. H. Fujii, M. Ide, and S. Yasuda Increased FDG uptake in the wall of the right atrium in people who participated in a cancer screening program with whole-body PET Ann Nucl Med 13 1999 55 59
28. M. Meka, E.G. Depuey, and P. Bhargava Focal FDG activity in the region of right atrium: coregistered CT identifies three benign etiologies Radiol Case Rep [Online] 3 2008 120
29. G.K. von Schulthess Clinical molecular anatomic imaging G.K. von Schulthess, Normal PET and PET/CT body scans: imaging pitfalls and artifacts 2002 Lippincott, Williams & Wilkins Baltimore, MD 252 270
30. 18F fluorodeoxyglucose positron emission tomography/CT Chest 128 2005 3888 3893
31. C.M. Fan, A.J. Fischman, and B.H. Kwek Lipomatous hypertrophy of the interatrial septum: increased uptake on FDG PET AJR Am J Roentgenol 184 2005 339 342
32. P.S. Gerard, H. Finestone, and R. Lazzaro Intermittent FDG uptake in lipomatous hypertrophy of the interatrial septum on serial PET/CT scans Clin Nucl Med 33 2008 602 605
33. S. Kim, Y.G. Ding, and B.R. Krynyckyi Increased F-18 FDG uptake in the right auricle of a displaced heart: potential cause of a false-positive pathologic mediastinal node Clin Nucl Med 30 2005 97 99
34. B.D. Nguyen PET demonstration of left atrial appendage in chronic atrial fibrillation Clin Nucl Med 30 2005 177 179
35. I. Biancheri, R. Zsigmond, and O. Angoue F-18 FDG PET identification of right atrium metastasis from a vesical carcinoma Clin Nucl Med 32 2007 812 815
36. J.R. Garcia, M. Simo, and M. Huguet Usefulness of 18-fluorodeoxyglucose positron emission tomography in the evaluation of tumor cardiac thrombus from renal cell carcinoma Clin Transl Oncol 8 2006 124 128
37. Y. Lu, and G. Ulaner FDG PET/CT demonstration of right atrium metastasis overlooked on contrast-enhanced CT Clin Nucl Med 36 2011 405 406
38. M.V. Orcurto, A.B. Delaloye, and I. Letovanec Detection of an asymptomatic right-ventricle cardiac metastasis from a small-cell lung cancer by F-18-FDG PET/CT J Thorac Oncol 4 2009 127 130
39. E.C. Lin Isolated papillary muscle uptake on FDG PET/CT Clin Nucl Med 32 2007 76 78
40. R. Kluge, H. Barthel, and H. Pankau Different mechanisms for changes in glucose uptake of the right and left ventricular myocardium in pulmonary hypertension J Nucl Med 46 2005 25 31
41. T.C. Yeo, K.S. Dujardin, and C. Tei Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension Am J Cardiol 81 1998 1157 1161
42. M.T. Truong, J.J. Erasmus, and R.F. Munden Focal FDG uptake in mediastinal brown fat mimicking malignancy: a potential pitfall resolved on PET/CT AJR Am J Roentgenol 183 2004 1127 1132
43. W. Sureshbabu, and O. Mawlawi PET/CT imaging artifacts J Nucl Med Technol 33 2005 156 161 quiz 163-154
44. P. Ghafarian, S.M. Aghamiri, and M.R. Ay Is metal artefact reduction mandatory in cardiac PET/CT imaging in the presence of pacemaker and implantable cardioverter defibrillator leads? Eur J Nucl Med Mol Imaging 38 2011 252 262
45. C. Altehoefer LBBB: challenging our concept of metabolic heart imaging with fluorine-18-FDG and PET? J Nucl Med 39 1998 263 265
46. P.G. Masci, M. Marinelli, and M. Piacenti Myocardial structural, perfusion, and metabolic correlates of left bundle branch block mechanical derangement in patients with dilated cardiomyopathy: a tagged cardiac magnetic resonance and positron emission tomography study Circ Cardiovasc Imaging 3 2010 482 490
47. K. Thompson, G. Saab, and D. Birnie Is septal glucose metabolism altered in patients with left bundle branch block and ischemic cardiomyopathy? J Nucl Med 47 2006 1763 1768
48. P. Zanco, A. Desideri, and G. Mobilia Effects of left bundle branch block on myocardial FDG PET in patients without significant coronary artery stenoses J Nucl Med 41 2000 973 977
49. M.N. Cho, S.K. Mehta, and S. Matulevicius Differentiating true versus pseudo left ventricular aneurysm: a case report and review of diagnostic strategies Cardiol Rev 14 2006 e27 30
50. G. Zoffoli, D. Mangino, and A. Venturini Diagnosing left ventricular aneurysm from pseudo-aneurysm: a case report and a review in literature J Cardiothorac Surg 4 2009 11
51. J.S. Park, I.H. Cho, and D.G. Shin Hypertrophic cardiomyopathy complicated by left ventricular apical necrosis and aneurysm in a young man: FDG-PET findings Korean J Intern Med 22 2007 28 31
52. D. Shao, S.X. Wang, and C.H. Liang Differentiation of malignant from benign heart and pericardial lesions using positron emission tomography and computed tomography J Nucl Cardiol 18 2011 668 677
53. N. Pandit, and H.W. Yeung F-18 FDG pericardial uptake secondary to recent cardiac surgery Clin Nucl Med 26 2001 984 985
54. 18F-fluorodeoxyglucose positron emission tomography: a report of two cases Ann Nucl Med 24 2010 421 425
55. S.B. Losik, Y. Studentsova, and D. Margouleff Chemotherapy-induced pericarditis on F-18 FDG positron emission tomography scan Clin Nucl Med 28 2003 913 915
56. O.G. James, J.D. Christensen, and T.Z. Wong Utility of FDG PET/CT in inflammatory cardiovascular disease RadioGraphics 31 2011 1271 1286
57. K. Strobel, R. Schuler, and M. Genoni Visualization of pericarditis with fluoro-deoxy-glucose-positron emission tomography/computed tomography Eur Heart J 29 2008 1212
58. V. Sekhri, S. Sanal, and L.J. Delorenzo Cardiac sarcoidosis: a comprehensive review Arch Med Sci 7 2011 546 554
59. C. Chapelon-Abric, D. de Zuttere, and P. Duhaut Cardiac sarcoidosis: a retrospective study of 41 cases Medicine (Baltimore) 83 2004 315 334
60. V. Jain, S. Hasselquist, and M.D. Delaney PET scanning in sarcoidosis Ann N Y Acad Sci 1228 2011 46 58
61. K. Iwai, T. Takemura, and M. Kitaichi Pathological studies on sarcoidosis autopsy. II. Early change, mode of progression and death pattern Acta Pathol Jpn 43 1993 377 385
62. A. Uemura, S. Morimoto, and S. Hiramitsu Histologic diagnostic rate of cardiac sarcoidosis: evaluation of endomyocardial biopsies Am Heart J 138 1999 299 302
63. M. Sekiguchi, Y. Yazaki, and M. Isobe Cardiac sarcoidosis: diagnostic, prognostic, and therapeutic considerations Cardiovasc Drugs Ther 10 1996 495 510
64. A. Perry, and F. Vuitch Causes of death in patients with sarcoidosis. A morphologic study of 38 autopsies with clinicopathologic correlations Arch Pathol Lab Med 119 1995 167 172
65. 18F-FDG PET in the diagnosis of cardiac sarcoidosis: a systematic review and metaanalysis including the Ontario experience J Nucl Med 53 2012 241 248
66. N. Tahara, A. Tahara, and Y. Nitta Heterogeneous myocardial FDG uptake and the disease activity in cardiac sarcoidosis JACC Cardiovasc Imaging 3 2010 1219 1228
67. R. Matthews, T. Bench, and H. Meng Diagnosis and monitoring of cardiac sarcoidosis with delayed-enhanced MRI and (18)F-FDG PET-CT J Nucl Cardiol 19 2012 807 810
68. 18F-fluoro-2-deoxyglucose positron emission tomography and magnetic resonance imaging in sarcoidosis Eur J Nucl Med Mol Imaging 35 2008 933 941
69. E. Tadamura, M. Yamamuro, and S. Kubo Effectiveness of delayed enhanced MRI for identification of cardiac sarcoidosis: comparison with radionuclide imaging AJR Am J Roentgenol 185 2005 110 115
70. D. Agostini, G. Babatasi, and F. Galateau Detection of cardiac myxoma by F-18 FDG PET Clin Nucl Med 24 1999 159 160
71. I. Martinez-Rodriguez, I. Banzo, and R. Quirce F-18 FDG PET/CT uptake by a cardiac hemangioma Clin Nucl Med 35 2010 330 331
72. C. Godino, C. Messa, and L. Gianolli Multifocal, persistent cardiac uptake of [18-F]-fluoro-deoxy-glucose detected by positron emission tomography in patients with acute myocardial infarction Circ J 72 2008 1821 1828
73. 18F- fluorodeoxyglucose positron emission tomography for early diagnosis of radiation-induced myocardial damage Int J Radiat Oncol Biol Phys 66 2006 845 851
74. F.J. Vos, C.P. Bleeker-Rovers, and B.J. Kullberg Cost-effectiveness of routine (18)F-FDG PET/CT in high-risk patients with Gram-positive bacteremia J Nucl Med 52 2011 1673 1678
75. C.L. Yeh, J.Y. Liou, and S.W. Chen Infective endocarditis detected by (1)(8)F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography in a patient with occult infection Kaohsiung J Med Sci 27 2011 528 531
76. R.F. Yen, Y.C. Chen, and Y.W. Wu Using 18-fluoro-2-deoxyglucose positron emission tomography in detecting infectious endocarditis/endoarteritis: a preliminary report Acad Radiol 11 2004 316 321
77. S. Moghadam-Kia, A. Nawaz, and B.C. Millar Imaging with (18)F-FDG-PET in infective endocarditis: promising role in difficult diagnosis and treatment monitoring Hell J Nucl Med 12 2009 165 167
78. 18F-FDG uptake J Nucl Med 48 2007 234 239
79. K.A. Gurney, and R.A. Cartwright Increasing incidence and descriptive epidemiology of extranodal non-Hodgkin lymphoma in parts of England and Wales Hematol J 3 2002 95 104
80. P.J. McDonnell, R.B. Mann, and B.H. Bulkley Involvement of the heart by malignant lymphoma: a clinicopathologic study Cancer 49 1982 944 951
81. C.D. Petersen, W.A. Robinson, and J.E. Kurnick Involvement of the heart and pericardium in the malignant lymphomas Am J Med Sci 272 1976 161 165
82. S. Rao, A. Langston, and J.R. Galt Extramedullary acute myeloid leukemia and the use of FDG-PET/CT Clin Nucl Med 34 2009 365 366
83. G. Acikgoz, M. Houseni, and K. Alkhawaldeh Detection of extramedullary and extranodal involvement of leukemia with FDG-PET J Nucl Med 47 Suppl. 1 2006 51P
84. 18F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia Haematologica 96 2011 1552 1556
85. G. Acikgoz, M. Houseni, and M. Bathaii FDG-PET evaluation of patients with leukemia J Nucl Med 47 Suppl. 1 2006 50P
86. M. Nakajo, S. Jinnouchi, and H. Inoue FDG PET findings of chronic myeloid leukemia in the chronic phase before and after treatment Clin Nucl Med 32 2007 775 778
87. H.A. Mcallister, and J.J. Fenoglio Tumors of the cardiovascular system 1979 Castle House Publications Washington, DC
88. T.R. Johnson, C.R. Becker, and B.J. Wintersperger Images in cardiovascular medicine. Detection of cardiac metastasis by positron-emission tomography-computed tomography Circulation 112 2005 e61 62
89. A.P. Burke, D. Cowan, and R. Virmani Primary sarcomas of the heart Cancer 69 1992 387 395
90. W. Bouma, C.P. Lexis, and T.P. Willems Successful surgical excision of primary right atrial angiosarcoma J Cardiothorac Surg 6 2011 47
91. L.S. Freudenberg, S.J. Rosenbaum, and J. Schulte-Herbruggen Diagnosis of a cardiac angiosarcoma by fluorine-18 fluordeoxyglucose positron emission tomography Eur Radiol 12 Suppl. 3 2002 S158 S161
92. Y. Hori, N. Funabashi, and H. Miyauchi Angiosarcoma in the right atria demonstrated by fusion images of multislice computed tomography and positron emission tomography using F-18 fluoro-deoxyglucose Int J Cardiol 123 2007 e15 17
93. P. Ost, S. Rottey, and P. Smeets F-18 fluorodeoxyglucose PET/CT scanning in the diagnostic work-up of a primary pericardial mesothelioma: a case report J Thorac Imaging 23 2008 35 38