Phototoxicity of kava - Formation of reactive oxygen species leading to lipid peroxidation and DNA damage

American Journal of Chinese Medicine

Volumn 40, Issue 6, 2012, Pages 1271-1288

  Xia, Qingsu ^a   Chiang, Hsiu Mei ^b   Zhou, Yu Ting ^c   Yin, Jun Jie ^c   Liu, Fang ^a   Wang, Cheng ^a   Guo, Lei ^a   Fu, Peter P ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

8 OHdG; HaCaT Keratinocytes; Kava Extract; Lipid Peroxidation; Photosensitivity; Reactive Oxygen Species; UVA Light

Indexed keywords

7,8 DIHYDROKAWAIN; 7,8 DIHYDROMETHYSTICIN; 8 HYDROXYDEOXYGUANOSINE; CARBON; DEMETHOXYYANGONIN; HYDROXYL RADICAL; KAVA; KAVA EXTRACT; KAWAIN; LINOLEIC ACID METHYL ESTER; LIPID; METHYSTICIN; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; YANGONIN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA CLEAVAGE; DNA DAMAGE; DNA STRAND; DNA SUPERCOILING; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LIPID PEROXIDATION; OXIDATIVE STRESS; PHOTOTOXICITY; ULTRAVIOLET A RADIATION;

CELL LINE; DNA DAMAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; KAVA; LIPID PEROXIDATION; REACTIVE OXYGEN SPECIES;

EID: 84871301903     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X12500942     Document Type: Article

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