Co-localization of NANOG and OCT4 in human pre-implantation embryos and in human embryonic stem cells

Journal of Assisted Reproduction and Genetics

Volumn 29, Issue 10, 2012, Pages 1021-1028

  Hambiliki, Fredwell ^a,b   Ström, Susanne ^a   Zhang, Pu ^b   Stavreus Evers, Anneli ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Embryo; Embryonic stem cells; In situ hybridization; NANOG; Pluripotency

Indexed keywords

MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG;

ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; EMBRYONIC STEM CELL; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACYTOPLASMIC SPERM INJECTION; MORULA; PLURIPOTENT STEM CELL; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

BLASTOCYST; FEMALE; FERTILIZATION IN VITRO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; IN SITU HYBRIDIZATION; MORULA; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS;

MURINAE;

EID: 84871294371     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9824-9     Document Type: Article

References (34)

1. Bjuresten K, Hovatta O. Donation of embryos for stem cell research - how many couples consent? Hum Reprod. 2003;18:1353-5.
2. Buehr M, Smith A. Genesis of embryonic stem cells. Philos Trans R Soc Lond B Biol Sci. 2003;358:1397-4402.
3. Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A. Functional expression cloning of NANOG, a pluripotency sustaining factor in Embronic Stem cells. Cell. 2003;113:643-55.
4. Chambers I, Smith A. Self renewal of teratocarcinoma and embryonic stem cells. Oncogene. 2004;23:7150-60.
5. Du Puy L, Lopes SM, Haagsman HP, Roelen BA. Analysis of coexpression of OCT4, NANOG and SOX2 in pluripotent cells of the porcine embryo, in vivo and in vitro. Therienology. 2011;75:513-26.
6. Galán A, Montaner D, Póo E, Valbuena D, Ruiz V, Aguillar C, Dopazo J, Simon C. Functional genomics of 5- to 8-cell stage human embryos to blastomere single-cell cDNA analysis. PLoS One. 2010;5:e13615.
7. Göke J, Jung M, Behrens S, Chavez L, O'Keeffe S, Timmermann B, Lehrach H, Adjaye J, Vingron M. Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development. PLoS Comput Biol. 2011;7:e1002304.
8. Hart AH, Hartley L, Ibrahim M, Robb L. Identification, cloning and expression analysis of the pluripotency promoting NANOG genes in mouse and human. Dev Dyn. 2004;230:187-98.
9. Hansis C, Grifo JA, Krey LC. Oct-4 expression in inner cell mass and trophectoderm of human blastocysts. Mol Hum Reprod. 2000;6:999-1004.
10. Hansis C, Grifo JA, Tang Y, Krey LC. Assessment of beta-hCG and beta LH mRNA and ploidy in individual human blastomeres. RBM Online. 2002;5:156-61.
11. Hansis C, Edwards RG. Cell differentiation in the preimplantation human embryo. RBM Online. 2002;6:215-20.
12. Hatano SY, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T, Suemori H, Nakatsuji N, Tada T. Pluripotential competence of cells associated with NANOG activity. Mech Dev. 2005;122:67-79.
13. Hovatta O, Mikkola M, Gertow K, Stromberg AM, Inzunza J, Hreinsson J, Rozell B, Blennow E, Andang M, Ahrlund-Richter L. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod. 2003;18:1404-9.
14. Inzunza J, Gertow K, Stromberg MA, Matilainen E, Blennow E, Skottman H, Wolbank S, Ahrlund-Richter L, Hovatta O. Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells. Stem Cells. 2005;23:544-9.
15. Kimber SJ, Snedden SF, Bloor DJ, El-Bareg AM, Hawkhead JA, Metcalfe AD, Houghton FD, Leese HJ, Rutherford A, Lieberman BA, Brison DR. Expression of genes involved in early cell fate decisions in human embryos and their regulation by growth factors. Reproduction. 2008;135:635-47.
16. Kirchhof N, Carnwath JW, Lemme E, Anastassiadis K, Scholer H, Niemann H. Expression pattern of Oct-4 in preimplantation embryos of different species. Biol Reprod. 2000;63:1698-705.
17. Kuroda T, Tada M, Kubota H, Kimura H, Hatano SY, Suemori H, Nakatsuji N, Tada T. Octamer and Sox elements are required for transcriptional cis regulation of NANOG gene expression. Mol Cell Biol. 2005;25:2475-85.
18. Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. The homeoprotein NANOG is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003;113:631-6642.
19. Mohr L, Trounson A. Cryopreservation of human embryos. Ann N Y Acad Sci. 1985;442:536-43.
20. Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Scholer H, Smith A. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor OCT4. Cell. 1998;95:379-91.
21. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet. 2000;24:372-6.
22. Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell. 1990;60:461-72.
23. Osterlund C, Wramsby H, Pousette A. Temporal expression of platelet-derived growth factor (PDGF)-A and its receptor in human preimplantation embryos. Mol Hum Reprod. 1996;2:507-12.
24. Palmieri SL, Peter W, Hess H, Scholer HR. Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol. 1994;166:259-67.
25. Reubinoff BE, Pera MF, Vajta G, Trounson AO. Effective cryopreservation of human embryonic stem cells by the open pulled straw vitrification method. Hum Reprod. 2001;16:2187-94.
26. Rosner MH, Vigano MA, Ozato K, Timmons PM, Poirier F, Rigby PW, Staudt LM. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 1990;345:686-92.
27. Scholer HR, Dressler GR, Balling R, Rohdewohld H, Gruss P. Oct-4: a germline-specific transcription factor mapping to the mouse tcomplex. EMBO J. 1990;9:2185-95.
28. Silva J, Nichols JM, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A. NANOG is the gateway to the pluripotent ground state. Cell. 2009;138:722-37.
29. Smith AG. Embryo-derived stem cells: of mice and men. Ann Rev Cell Dev Biol. 2001;17:435-62.
30. Solter D, Knowles BB. Immunosurgery of mouse blastocyst. Proc Natl Acad Sci USA. 1975;72:5099-102.
31. Van Blerkom J, Davis P, Mathwig V, Alexander S. Domains of high polarized and low polarized mitochondria may occur in mouse and human oocytes and early embryos. Hum Reprod. 2002;17:393-406.
32. Van Eijk MJ, van Rooijen MA, Modina S, Scesi L, Folkers G, van Tol HT, Bevers MM, Fisher SR, Lewin HA, Rakacolli D, et al. Molecular cloning, genetic mapping, and developmental expression of bovine POU5F1. Biol Reprod. 1999;60:1093-103.
33. Yeom YI, Fuhrmann G, Ovitt CE, Brehm A, Ohbo K, Gross M, Hubner K, Scholer HR. Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development. 1996;122:881-94.
34. Zhang P, Zucchelli M, Bruce S, Hambiliki F, Stavreus-Evers A, Levkov L, Skottman H, Kerkelä E, Kere J, Hovatta O. Transcriptome profiling of human pre-implantation development. PLoS One. 2009;4(11):e7844.