Moderate hypoxia/hyperoxia attenuates acute hypoxia-induced oxidative damage and improves antioxidant defense in lung mitochondria

Acta Physiologica Hungarica

Volumn 99, Issue 4, 2012, Pages 436-446

  Gonchar, Olga ^a   Mankovska, I ^a  

^a INSTITUTE OF HYDROBIOLOGY   (Ukraine)

Author keywords

glutathione system; hypoxia hyperoxia; lung; mitochondria; MnSOD; protein and mRNA expression

Indexed keywords

FREE RADICAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; HYPEROXIA; HYPOXIA; LIPID PEROXIDATION; LUNG; MALE; MITOCHONDRION; NONHUMAN; PROTEIN SYNTHESIS; RAT;

ACUTE DISEASE; ANIMALS; ANOXIA; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; GLUTATHIONE; HOMEOSTASIS; HYPEROXIA; LIPID PEROXIDATION; LUNG; MALE; MITOCHONDRIA; MITOCHONDRIAL DISEASES; OXIDATIVE STRESS; RATS; RATS, WISTAR; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SUPEROXIDE DISMUTASE;

EID: 84871291562     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.99.2012.4.8     Document Type: Article

References (40)

1. Anderson M: Determination of glutathione and glutathione disulfde in biological samples. Methods Enzymol. 113, 548-551 (1985)
2. Bigdeli M: Preconditioning with prolonged normobaric hyperoxia induces ischemic tolerance partly by upregulation of antioxidant enzymes in rat brain tissue. Brain Res. 1260, 47-54 (2009)
3. Buege J, Aust S: Microsomal lipid peroxidation. Methods Enzymol. LII, 302-308 (1978)
4. Carlberg I, Mannervik B: Glutathione reductase. Methods Enzymol. 113, 484-490 (1985)
5. Cruthirds D, Novak L, Akhi K, Sanders P, Thompson J, Mac Millan-Crow L: Mitochondrial targets of oxidative stress during renal ischemia/reperfusion. Arch. Biochem. Biophys. 412, 27-33 (2003)
6. Dickinson DA, Forman HJ: Cellular glutathione and thiols metabolism. Biochem. Pharmacol. 64, 1019-1026 (2002)
7. 2+ on substrate utilization. Biochem. 7, 1438-1445 (1973)
8. Gonchar O, Mankovskaya I: Effect of moderate hypoxia/reoxygenation on mitochondrial adaptation to acute severe hypoxia. Acta Biol. Hungarica 60, 185-194 (2009)
9. Gonchar O: Effect of intermittent hypoxia different regimes on mitochondrial lipid peroxidation and glutathione-redox balance in stressed rats. Cent. Eur. J. Biol. 3, 233-242 (2008)
10. Ho Y, Dey M, Crapo J: Antioxidant enzyme expression in rat lungs during hyperoxia. Am. J. Physiol. 270, L810-L818 (1996)
11. Jackson R, Parish G, Ho Y: Effects of hypoxia on expression of superoxide dismutases in cultured AT II cells and lung fbroblasts. Am. J. Physiol. Lung Cell Mol. Physiol. 271, L955-L962 (1996)
12. Jezek P, Hlavata L: Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int. J. Biochem. & Cell Biol. 37, 2478-2503 (2005)
13. Kiselev SO: The mechanism of action of HBO on the organism. Hyperbaric Physiol. Med. 2, 3-7 (2002) [in Russian]
14. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970)
15. Lebowitz R, Zhang H, Vogel H, Cartwright Jr, Dionne L, Lu N, Huang S, Matzuk M: Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxidase-defcient mice. Proc. Natl Acad. Sci. USA. 93, 9782-9787 (1996)
16. Lee E, Smith W, Quach H, Jones B: Moderate hyperoxia (40%) increases antioxidant levels in mouse tissue. J. Surg. Res. 127, 80-84 (2005)
17. Lluis J, Morales A, Blasco C, Colell A, Mari M, Garcia-Ruiz C, Fernandez-Checa C: Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia. J. Biol. Chem. 280, 3224-3232 (2005)
18. Lukyanova LD (2005): Novel approach to the understanding of molecular mechanisms of adaptation to hypoxia. In: Adaptation Biology and Medicine, eds Hargens A, Takeda N, Singal P, Vol. 4. Current Concepts, New Delhi, Narosa, pp. 1-19
19. MacMilan-Crow LA, Crow JP, Thompson JA: Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry 37, 1613-1622 (1998)
20. Mankovska I, Gavenauskas B, Nosar V, Gonchar O, Bratus L, Kurhalyuk N (2009): Effects of intermittent hypoxia on oxygen-dependent processes in skeletal muscle under endurance training. In: Intermittent hypoxia: from molecular mechanisms to clinical Application, eds Lei Hi, Serebrovskaya T, Nova Science Publishers Inc., New York, pp. 519-533
21. Mansfeld K, Simon M, Keith B: Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species. J. Appl. Physiol. 97, 1358-1366 (2004)
22. Maslov VF, Sazontova TG, Kostin AI: Free radical oxidation in treatment of patients with ischemic heart disease therapy by intermittent hypoxia and hyperoxia. Hypoxia Med. J. 1-2, 23-26 (2004)
23. Misra H, Fridovich I: The role of superoxide anion in the autoxidation of epinephrine and a simple assay superoxide dismutase. J. Biol. Chem. 247, 3170-3175 (1972)
24. Pardo M, Tirosh O: Protective signaling effect of manganese superoxide dismutase in hypoxia-reoxygenation of hepatocytes. Free Rad. Res. 43, 1225-1239 (2009)
25. Pardo M, Budick-Harmelin N, Tirosh B, Tirosh O: Antioxidant defense in hepatic ischemia-reperfusion injury is regulated by damage-associated molecular pattern signal molecules. Free Radic. Biol. Med. 45, 1073-1083 (2008)
26. Rahman I, MacNee W: Oxidative stress and regulation of glutathione in lung infammation. Eur. Respir. J. 16, 534-554 (2000)
27. Rahman I, Antonicelli F, MacNee W: Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-α and dexamethasone in human alveolar epithelial cells. J. Biol. Chem. 274, 5088-5096 (1999)
28. Rotruck JT, Pope AL, Ganther H E, Swanson AB: Selenium: biochemical role as a component of glutathione peroxidase. Science 179, 588-590 (1973)
29. Russell W, Ho Y, Jackson R: Effects of hypoxia on MnSOD expression in mouse lung. Am. J. Physiol. 269, L221-L226 (1995)
30. Russell W, Jackson R: MnSOD protein content changes in hypoxic/hypoperfused lung tissue. Am. J. Respir. Cell Mol. Biol. 9, 610-616 (1993)
31. Sazontova TG, Anchidhkina NA, Zhukova AG, Bedareva IV, Pylaeva EA, Krivencova NA, Polianskaya AA, Iurasov AR, Arhipenko YV: Active oxygen forms and redox-signaling role in adaptation to oxygen contents changing. Fisiol J. 2, 18-32 (2008) [in Russian]
32. Sazontova TG, Arhipenko YV (2009): Intermittent hypoxia in resistance of cardiac membrane structures: role of reactive oxygen species and redox signaling. In: Intermittent hypoxia: from molecular mechanisms to clinical application, eds Lei Hi, Serebrovskaya T, Nova Science Publishers Inc., New York, pp. 113-150
33. Sen C, Packer L: Antioxidant and redox regulation of gene transcription. FASEB J. 10, 709-720 (1996)
34. ®. 1, 26-35 (2004)
35. Shen C, Lee J, Su C, Wang D, Chen C: Hypoxia and reoxygenation of the lung tissues induced m RNA expressions of superoxide dismutase and catalase and interventions from different antioxidants. Transplant Proc. 40, 182-184 (2008)
36. Tkachouk E, Gorbachenkov A, Kolchinskaya A, Ehrenburg I (1994): Adaptation to interval hypoxia for prophylaxis and therapy. Hypoxia Med. Ltd, Moscow, Russia
37. Tsan MF: Superoxide dismutase and pulmonary oxygen toxicity: lessons from transgenic and knockout mice. Int. J. Mol. Med.7, 13-19 (2001)
38. Vincent R, Chang L, Slot J, Crapo J: Quantitative immunocytochemical analysis of MnSOD in alveolar type II cells of the hyperoxic rat. Am. J. Physiol. 267, L475-L481 (1994)
39. Warholm M, Guthenberg C, Bahr C, Mannervik B: Glutathione transferases from human liver. Methods Enzymol. 113, 499-501 (1985)
40. Warner B, Stuart L, Gebb S, Wispe J: Redox regulation of manganese superoxide dismutase. Am. J. Physiol. Lung Cell. Mol. Physiol. 271, L150-L158 (1996)