Significance of lipopolysaccharides, toll-like receptor and inducible nitric oxide synthase in hepatopulmonary syndrome

National Medical Journal of China

Volumn 89, Issue 22, 2009, Pages 1521-1524

  Yi, Hui Min ^a   Wang, Gen Shu ^a   Cai, Chang Jie ^a   Yang, Yang ^a   Lu, Min Qiang ^a   Hu, Bin ^b   Chen, Gui Hua ^a  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b NONE

Author keywords

Hepatopulmonary syndrome; Orthotopic liver transplantation; Real time fluorescent quantitative PCR

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NOS2A PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 2;

ADULT; AGED; ARTICLE; BLOOD; FEMALE; HEPATOPULMONARY SYNDROME; HUMAN; MALE; METABOLISM; MIDDLE AGED; MONOCYTE; POLYMERASE CHAIN REACTION;

ADULT; AGED; FEMALE; HEPATOPULMONARY SYNDROME; HUMANS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; MONOCYTES; NITRIC OXIDE SYNTHASE TYPE II; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2;

EID: 84871289900     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2009.22.005     Document Type: Article

References (12)

1. Perkins JD. Diagnosing hepatopulmonary syndrome. Liver Transpl, 2007, 13: 1464-1465.
2. Roberto Rodríguez-Roisin, Krowka MJ. Hepatopulmonary syndrome-a liver-induced lung vascular disorder. N Engl J Med, 2008, 358: 2378-2387.
3. 2006, 33: 41-43.
4. Agrawal G, Kumar N, Rosha D. Hepatopulmonary syndrome. J Assoc Physicians India, 2008, 56: 265-267.
5. Kropf P. Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major. Infect Immun, 2004, 72: 1920-1928.
6. He HQ, Genovese KJ, Nisbet DJ, et al. Profile of Toll-like receptor expressions and induction of nitric oxide synthesis by Tolllike receptor agonists in chicken monocytes. Molecular Immunology, 2006, 43: 783-789.
7. Ojaniemi M, Liljeroos M, Harju K, et al. TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice. Immunology Letters, 2006, 102: 158-168.
8. Riordan SM, Skinner N, Nagree A, et al. Peripheral blood mononuclear cell expression of Toll-like receptors and relation to cytokine levels in cirrhosis. Hepatology, 2003, 37: 1154-1164.
9. Paik YH, Schwabe RF, Bataller R, et al. Toll-Like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology, 2003, 37: 1043-1055.
10. 2005, 85: 1468-1472.
11. 2005, 21: 2238-2242.
12. Sztrymf B, Libert JM, Mougeot C, et al. Cirrhotic rats with bacterial translocation have higher incidence and severity of hepatopulmonary syndrome. J Gastroenterol Hepatol, 2005, 20: 1538-1544.