Haworforbins A-C, new phenolics from Haworthia cymbiformis

Journal of Natural Medicines

Volumn 67, Issue 1, 2013, Pages 212-216

  Yamasaki, Fumie ^a   Machida, Shoko ^a   Nakata, Asami ^a   Nugroho, Alfarius Eko ^a   Hirasawa, Yusuke ^a   Kaneda, Toshio ^a   Shirota, Osamu ^b   Hagane, Naoyuki ^c   Sugizaki, Tadayoshi ^c   Morita, Hiroshi ^a  

^a HOSHI UNIVERSITY   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^c Sabotensoudanshitsu   (Japan)

Author keywords

Haworforbins A C; Haworthia cymbiformis; iNOS production inhibition activity

Indexed keywords

CHLOROFORM; COUMARIN; GLUCOSIDE; HAWORFORBIN A; HAWORFORBIN B; HAWORFORBIN C; LIPOPOLYSACCHARIDE; METHYL GROUP; NITRIC OXIDE; PHENOL DERIVATIVE; UNCINOSIDE A; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CIRCULAR DICHROISM; DRUG ISOLATION; DRUG STRUCTURE; HAWORTHIA CYMBIFORMIS; HETERONUCLEAR MULTIPLE BOND CORRELATION; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE;

ANGIOSPERMS; ANIMALS; CELL LINE; GLUCOSIDES; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS;

EID: 84871287392     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-012-0647-x     Document Type: Article

References (10)

1. Hosoya T, Yamasaki F, Nakata A, Rahman A, Kusumawati I, Zaini NC, Morita H (2011) Inhibitors of nitric oxide production from Stemona javanica. Planta Med 77(256):258
2. Morita H, Oshimi S, Hirasawa Y, Koyama K, Honda T, Ekasari W, Indrayanto G, Zaini NC (2007) Cassiarins A and B, novel antiplasmodial alkaloids from Cassia siamea. Org Lett 9:3691-3693
3. Hirasawa Y, Hara M, Nugroho AE, Sugai M, Zaima K, Kawahara N, Goda Y, Awang K, Hadi AHA, Litaudon M, Morita H (2010) Bisnicalaterines B and C, atropisomeric bisindole alkaloids from Hunteria zeylanica, showing vasorelaxant activity. J Org Chem 75:4218-4223
4. Hirasawa Y, Shoji T, Arai T, Nugroho AE, Deguchi J, Hosoya T, Uchiyama N, Goda Y, Awang K, Hadi AHA, Shiro M, Morita H (2010) Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii. Bioorg Med Chem Lett 20:2021-2024
5. Koyama K, Hirasawa Y, Hosoya T, Hoe TC, Chan K-L, Morita H (2010) Alpneumines A-H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora. Bioorg Med Chem 18:4415-4421
6. Ma L-Y, Ma S-C, Wei F, Lin R-C, But PP-H, Lee SH-S, Lee SF (2003) Uncinoside A and B, two new antiviral chromone glycosides from Selaginella uncinata. Chem Pharm Bull 51:1264-1267 (Pubitemid 41685582)
7. Schlingmann G, Roll DM (2005) Absolute stereochemistry of unusual biopolymers from Ascomycete culture LL-W1278: examples that derivatives of (S)-6-hydroxymellein are also natural fungal metabolites. Chirality 17:S48-S51 (Pubitemid 40962062)
8. Kurosaki Y, Fukuda T, Iwao M (2005) Asymmetric synthesis of 3-substituted 3,4-dihydroisocoumarins via stereoselective addition of laterally lithiated chiral 2-(o-tolyl)oxazolines to aldehydes followed by diastereomer-selective lactonization. Tetrahedron 61:3289-3303 (Pubitemid 40349264)
9. Cheng M-J, Yang P-H, Wu M-D, Chen I-S, Hsieh M-T, Chen Y-L, Yuan G-F (2011) Secondary metabolites from the fungus Monascus purpureus and evaluation of their cytotoxic activity. Helv Chim Acta 94:1638-1650
10. Lewis CN, Staunton J, Sunter DC (1988) Biosynthesis of canescin, a metabolite of Aspergillus malignus: incorporation of methionine, acetate, succinate, and isocoumarin precursors, labelled with deuterium and carbon-13. J Chem Soc Perkin Trans 1:747-754