메뉴 건너뛰기




Volumn 93, Issue 1, 2013, Pages 68-77

New avenues for anticoagulation in atrial fibrillation

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; APIXABAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; DABIGATRAN; GLYCOPROTEIN P INHIBITOR; MENADIONE EPOXIDE; PROTON PUMP INHIBITOR; RIVAROXABAN; THROMBIN INHIBITOR; WARFARIN;

EID: 84871276049     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.197     Document Type: Article
Times cited : (22)

References (75)
  • 1
    • 0035832261 scopus 로고    scopus 로고
    • Prevalence of diagnosed atrial fibrillation in adults: National implications for rhythm management and stroke prevention: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
    • Go, A.S. et al. Prevalence of diagnosed atrial fibrillation in adults: National implications for rhythm management and stroke prevention: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA 285, 2370-2375 (2001).
    • (2001) JAMA , vol.285 , pp. 2370-2375
    • Go, A.S.1
  • 3
    • 0025779484 scopus 로고
    • Atrial fibrillation as an independent risk factor for stroke: The Framingham study
    • Wolf, P.A., Abbott, R.D. & Kannel, W.B. Atrial fibrillation as an independent risk factor for stroke: The Framingham study. Stroke. 22, 983-988 (1991).
    • (1991) Stroke , vol.22 , pp. 983-988
    • Wolf, P.A.1    Abbott, R.D.2    Kannel, W.B.3
  • 4
    • 0028244264 scopus 로고
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation Analysis of pooled data from five randomized controlled trials
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Arch Intern Med 154, 1449-1457 (1994).
    • (1994) Arch Intern Med , vol.154 , pp. 1449-1457
  • 5
    • 84856745317 scopus 로고    scopus 로고
    • Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • You, J.J. et al. Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141, e531S- e575S (2012).
    • (2012) Chest , vol.141
    • You, J.J.1
  • 6
    • 84856784474 scopus 로고    scopus 로고
    • Oral anticoagulant therapy: Antithrombotic therapy and prevention of thrombosis
    • 9th Ed: American College Of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Ageno, W., Gallus, A.S., Wittkowsky, A., Crowther, M., Hylek, E.M. & Palareti, G. Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141, e44S-e88S (2012).
    • (2012) Chest , vol.141
    • Ageno, W.1    Gallus, A.S.2    Wittkowsky, A.3    Crowther, M.4    Hylek, E.M.5    Palareti, G.6
  • 7
    • 19344366484 scopus 로고    scopus 로고
    • Systematic overview of warfarin and its drug and food interactions
    • Holbrook, A.M. et al. Systematic overview of warfarin and its drug and food interactions. Arch. Intern. Med. 165, 1095-1106 (2005).
    • (2005) Arch. Intern. Med , vol.165 , pp. 1095-1106
    • Holbrook, A.M.1
  • 8
    • 1942437369 scopus 로고    scopus 로고
    • The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage
    • Rosand, J., Eckman, M.H., Knudsen, K.A., Singer, D.E. & Greenberg, S.M. The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch. Intern. Med. 164, 880-884 (2004).
    • (2004) Arch. Intern. Med , vol.164 , pp. 880-884
    • Rosand, J.1    Eckman, M.H.2    Knudsen, K.A.3    Singer, D.E.4    Greenberg, S.M.5
  • 9
    • 0025241137 scopus 로고
    • The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation
    • The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators
    • The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. N. Engl. J. Med. 323, 1505-1511 (1990).
    • (1990) N. Engl. J. Med , vol.323 , pp. 1505-1511
  • 10
    • 0025914693 scopus 로고
    • Stroke prevention in atrial fibrillation study
    • Stroke Prevention in Atrial Fibrillation Study. Final results. Circulation 84, 527-539 (1991).
    • (1991) Final results. Circulation , vol.84 , pp. 527-539
  • 11
    • 2942696888 scopus 로고
    • Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke prevention in atrial fibrillation II study
    • Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke prevention in atrial fibrillation II study. Lancet 343, 687-691 (1994).
    • (1994) Lancet , vol.343 , pp. 687-691
  • 12
    • 0024543543 scopus 로고
    • Placebo-controlled randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation The Copenhagen AFASAK study
    • Petersen, P., Boysen, G., Godtfredsen, J., Andersen, E.D. & Andersen, B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Lancet 1, 175-179 (1989).
    • (1989) Lancet , vol.1 , pp. 175-179
    • Petersen, P.1    Boysen, G.2    Godtfredsen, J.3    Andersen, E.D.4    Andersen, B.5
  • 13
    • 34347394385 scopus 로고    scopus 로고
    • Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation
    • Hart, R.G., Pearce, L.A. & Aguilar, M.I. Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann. Intern. Med. 146, 857-867 (2007).
    • (2007) Ann. Intern. Med , vol.146 , pp. 857-867
    • Hart, R.G.1    Pearce, L.A.2    Aguilar, M.I.3
  • 14
    • 79960076271 scopus 로고    scopus 로고
    • Ischaemic stroke and bleeding rates in "Real-world" atrial fibrillation patients
    • Ogilvie, I.M., Welner, S.A., Cowell, W. & Lip, G.Y. Ischaemic stroke and bleeding rates in "real-world" atrial fibrillation patients. Thromb. Haemost. 106, 34-44 (2011).
    • (2011) Thromb. Haemost , vol.106 , pp. 34-44
    • Ogilvie, I.M.1    Welner, S.A.2    Cowell, W.3    Lip, G.Y.4
  • 15
    • 0035854054 scopus 로고    scopus 로고
    • Validation of clinical classification schemes for predicting stroke: Results from the National Registry of Atrial Fibrillation
    • Gage, B.F., Waterman, A.D., Shannon, W., Boechler, M., Rich, M.W. & Radford, M.J. Validation of clinical classification schemes for predicting stroke: Results from the National Registry of Atrial Fibrillation. JAMA 285, 2864-2870 (2001).
    • (2001) JAMA , vol.285 , pp. 2864-2870
    • Gage, B.F.1    Waterman, A.D.2    Shannon, W.3    Boechler, M.4    Rich, M.W.5    Radford, M.J.6
  • 16
    • 76749163232 scopus 로고    scopus 로고
    • Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The euro heart survey on atrial fibrillation
    • Lip, G.Y., Nieuwlaat, R., Pisters, R., Lane, D.A. & Crijns, H.J. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The euro heart survey on atrial fibrillation. Chest 137, 263-272 (2010).
    • (2010) Chest , vol.137 , pp. 263-272
    • Lip, G.Y.1    Nieuwlaat, R.2    Pisters, R.3    Lane, D.A.4    Crijns, H.J.5
  • 17
    • 33344461585 scopus 로고    scopus 로고
    • Clinical classification schemes for predicting hemorrhage: Results from the National Registry of Atrial Fibrillation (NRAF)
    • Gage, B.F. et al. Clinical classification schemes for predicting hemorrhage: Results from the National Registry of Atrial Fibrillation (NRAF). Am. Heart J. 151, 713-719 (2006).
    • (2006) Am. Heart J. , vol.151 , pp. 713-719
    • Gage, B.F.1
  • 18
    • 84865292043 scopus 로고    scopus 로고
    • Performance of the HEMORR (2)HAGES, ATRIA, and HAS-BLED Bleeding Risk-Prediction Scores in Patients With Atrial Fibrillation Undergoing Anticoagulation: The AMADEUS (Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation) Study
    • Apostolakis, S., Lane, D.A., Guo, Y., Buller, H. & Lip, G.Y. Performance of the HEMORR(2)HAGES, ATRIA, and HAS-BLED Bleeding Risk-Prediction Scores in Patients With Atrial Fibrillation Undergoing Anticoagulation: The AMADEUS (Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation) Study. J. Am. Coll. Cardiol. 60, 861-867 (2012).
    • (2012) J. Am. Coll. Cardiol. , vol.60 , pp. 861-867
    • Apostolakis, S.1    Lane, D.A.2    Guo, Y.3    Buller, H.4    Lip, G.Y.5
  • 19
    • 69849100157 scopus 로고    scopus 로고
    • The net clinical benefit of warfarin anticoagulation in atrial fibrillation
    • Singer, D.E. et al. The net clinical benefit of warfarin anticoagulation in atrial fibrillation. Ann. Intern. Med. 151, 297-305 (2009).
    • (2009) Ann. Intern. Med , vol.151 , pp. 297-305
    • Singer, D.E.1
  • 20
    • 22044452252 scopus 로고    scopus 로고
    • Avoiding central nervous system bleeding during antithrombotic therapy: Recent data and ideas
    • Hart, R.G., Tonarelli, S.B. & Pearce, L.A. Avoiding central nervous system bleeding during antithrombotic therapy: Recent data and ideas. Stroke. 36, 1588-1593 (2005).
    • (2005) Stroke , vol.36 , pp. 1588-1593
    • Hart, R.G.1    Tonarelli, S.B.2    Pearce, L.A.3
  • 21
    • 73249149518 scopus 로고    scopus 로고
    • Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: The ATRIA study
    • Singer, D.E. et al. Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: The ATRIA study. Circ. Cardiovasc. Qual. Outcomes 2, 297-304 (2009).
    • (2009) Circ. Cardiovasc. Qual. Outcomes , vol.2 , pp. 297-304
    • Singer, D.E.1
  • 22
    • 0041323099 scopus 로고    scopus 로고
    • Comparing the quality of oral anticoagulant management by anticoagulation clinics and by family physicians: A randomized controlled trial
    • Wilson, S.J. et al. Comparing the quality of oral anticoagulant management by anticoagulation clinics and by family physicians: A randomized controlled trial. CMAJ 169, 293-298 (2003).
    • (2003) CMAJ , vol.169 , pp. 293-298
    • Wilson, S.J.1
  • 23
    • 2342447949 scopus 로고    scopus 로고
    • Cost analysis of a managed care decentralized outpatient pharmacy anticoagulation service
    • Anderson, R.J. Cost analysis of a managed care decentralized outpatient pharmacy anticoagulation service. J. Manag. Care Pharm. 10, 159-165 (2004).
    • (2004) J. Manag. Care Pharm , vol.10 , pp. 159-165
    • Anderson, R.J.1
  • 24
    • 32544453399 scopus 로고    scopus 로고
    • New anticoagulants: Anti IIa vs anti Xa-is one better
    • Bauer, K.A. New anticoagulants: Anti IIa vs anti Xa-is one better? J. Thromb. Thrombolysis 21, 67-72 (2006).
    • (2006) J. Thromb Thrombolysis , vol.21 , pp. 67-72
    • Bauer, K.A.1
  • 25
    • 57449094606 scopus 로고    scopus 로고
    • Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development
    • Eriksson, B.I., Quinlan, D.J. & Weitz, J.I. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin. Pharmacokinet. 48, 1-22 (2009).
    • (2009) Clin. Pharmacokinet , vol.48 , pp. 1-22
    • Eriksson, B.I.1    Quinlan, D.J.2    Weitz, J.I.3
  • 26
    • 38749131205 scopus 로고    scopus 로고
    • The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
    • Blech, S., Ebner, T., Ludwig-Schwellinger, E., Stangier, J. & Roth, W. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab. Dispos. 36, 386-399 (2008).
    • (2008) Drug Metab. Dispos , vol.36 , pp. 386-399
    • Blech, S.1    Ebner, T.2    Ludwig-Schwellinger, E.3    Stangier, J.4    Roth, W.5
  • 27
    • 29144518504 scopus 로고    scopus 로고
    • Safety pharmacodynamics, and pharmacokinetics of BAY 59-7939-an oral, direct Factor Xa inhibitor-after multiple dosing in healthy male subjects
    • Kubitza, D., Becka, M., Wensing, G., Voith, B. & Zuehlsdorf, M. Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939-an oral, direct Factor Xa inhibitor-after multiple dosing in healthy male subjects. Eur. J. Clin. Pharmacol. 61, 873-880 (2005).
    • (2005) Eur. J. Clin. Pharmacol , vol.61 , pp. 873-880
    • Kubitza, D.1    Becka, M.2    Wensing, G.3    Voith, B.4    Zuehlsdorf, M.5
  • 28
    • 41949116970 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
    • Stangier, J. Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin. Pharmacokinet. 47, 285-295 (2008).
    • (2008) Clin. Pharmacokinet , vol.47 , pp. 285-295
    • Stangier, J.1
  • 29
    • 24944531701 scopus 로고    scopus 로고
    • Inhibition of Factor Xa: A potential target for the development of new anticoagulants
    • Alexander, J.H. & Singh, K.P. Inhibition of Factor Xa: A potential target for the development of new anticoagulants. Am. J. Cardiovasc. Drugs 5, 279-290 (2005).
    • (2005) Am. J. Cardiovasc. Drugs , vol.5 , pp. 279-290
    • Alexander, J.H.1    Singh, K.P.2
  • 30
    • 77749289263 scopus 로고    scopus 로고
    • Comparative efficacy and safety of the novel oral anticoagulants dabigatran, rivaroxaban and apixaban in preclinical and clinical development
    • Ufer, M. Comparative efficacy and safety of the novel oral anticoagulants dabigatran, rivaroxaban and apixaban in preclinical and clinical development. Thromb. Haemost. 103, 572-585 (2010).
    • (2010) Thromb. Haemost , vol.103 , pp. 572-585
    • Ufer, M.1
  • 31
    • 33947491766 scopus 로고    scopus 로고
    • Secondary stroke prevention with ximelagatran versus warfarin in patients with atrial fibrillation: Pooled analysis of SPORTIF III and V clinical trials
    • Akins, P.T. et al. Secondary stroke prevention with ximelagatran versus warfarin in patients with atrial fibrillation: Pooled analysis of SPORTIF III and V clinical trials. Stroke 38, 874-880 (2007).
    • (2007) Stroke , vol.38 , pp. 874-880
    • Akins, P.T.1
  • 32
    • 17444396697 scopus 로고    scopus 로고
    • Hepatic findings in long-term clinical trials of ximelagatran
    • Lee, W.M. et al. Hepatic findings in long-term clinical trials of ximelagatran. Drug Saf. 28, 351-370 (2005).
    • (2005) Drug Saf , vol.28 , pp. 351-370
    • Lee, W.M.1
  • 33
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly, S.J. et al. Dabigatran versus warfarin in patients with atrial fibrillation. N. Engl. J. Med. 361, 1139-1151 (2009).
    • (2009) N. Engl. J. Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1
  • 35
    • 77956977472 scopus 로고    scopus 로고
    • Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the RE-LY trial
    • Wallentin, L. et al. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the RE-LY trial. Lancet 376, 975-983 (2010).
    • (2010) Lancet , vol.376 , pp. 975-983
    • Wallentin, L.1
  • 36
    • 84863142762 scopus 로고    scopus 로고
    • Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial
    • Hohnloser, S.H. et al. Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial. Circulation 125, 669-676 (2012).
    • (2012) Circulation , vol.125 , pp. 669-676
    • Hohnloser, S.H.1
  • 37
    • 84857021520 scopus 로고    scopus 로고
    • Dabigatran association with higher risk of acute coronary events: Meta-analysis of noninferiority randomized controlled trials
    • Uchino, K. & Hernandez, A.V. Dabigatran association with higher risk of acute coronary events: Meta-analysis of noninferiority randomized controlled trials. Arch. Intern. Med. 172, 397-402 (2012).
    • (2012) Arch. Intern. Med , vol.172 , pp. 397-402
    • Uchino, K.1    Hernandez, A.V.2
  • 38
    • 84861659315 scopus 로고    scopus 로고
    • Dabigatran and myocardial infarction: Metaillusion
    • author reply 823
    • Correia, L.C. & Lopes, A.A. Dabigatran and myocardial infarction: Metaillusion? Arch. Intern. Med. 172, 823; author reply 823 (2012).
    • (2012) Arch. Intern. Med , vol.172 , pp. 823
    • Correia, L.C.1    Lopes, A.A.2
  • 39
    • 79957715797 scopus 로고    scopus 로고
    • Anticoagulant options-why the FDA approved a higher but not a lower dose of dabigatran
    • Beasley, B.N., Unger, E.F. & Temple, R. Anticoagulant options-why the FDA approved a higher but not a lower dose of dabigatran. N. Engl. J. Med. 364, 1788-1790 (2011).
    • (2011) N. Engl. J. Med , vol.364 , pp. 1788-1790
    • Beasley, B.N.1    Unger, E.F.2    Temple, R.3
  • 40
    • 80052592404 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
    • Patel, M.R. et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N. Engl. J. Med. 365, 883-891 (2011).
    • (2011) N. Engl. J. Med , vol.365 , pp. 883-891
    • Patel, M.R.1
  • 41
    • 79952301326 scopus 로고    scopus 로고
    • Apixaban in patients with atrial fibrillation
    • Connolly, S.J. et al. Apixaban in patients with atrial fibrillation. N. Engl. J. Med. 364, 806-817 (2011).
    • (2011) N. Engl. J. Med , vol.364 , pp. 806-817
    • Connolly, S.J.1
  • 42
    • 84865808575 scopus 로고    scopus 로고
    • An indirect comparison of dabigatran, rivaroxaban and apixaban for atrial fibrillation
    • Mantha, S. & Ansell, J. An indirect comparison of dabigatran, rivaroxaban and apixaban for atrial fibrillation. Thromb. Haemost. 108, 476-484 (2012).
    • (2012) Thromb. Haemost , vol.108 , pp. 476-484
    • Mantha, S.1    Ansell, J.2
  • 43
    • 84865138532 scopus 로고    scopus 로고
    • Indirect comparisons of new oral anticoagulant drugs for efficacy and safety when used for stroke prevention in atrial fibrillation
    • Lip, G.Y., Larsen, T.B., Skjøth, F. & Rasmussen, L.H. Indirect comparisons of new oral anticoagulant drugs for efficacy and safety when used for stroke prevention in atrial fibrillation. J. Am. Coll. Cardiol. 60, 738-746 (2012).
    • (2012) J. Am. Coll. Cardiol , vol.60 , pp. 738-746
    • Lip, G.Y.1    Larsen, T.B.2    Skjøth, F.3    Rasmussen, L.H.4
  • 44
    • 84865807336 scopus 로고    scopus 로고
    • Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis
    • Harenberg, J. et al. Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis. Int. Angiol. 31, 330-339 (2012).
    • (2012) Int. Angiol , vol.31 , pp. 330-339
    • Harenberg, J.1
  • 45
    • 79952445042 scopus 로고    scopus 로고
    • 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
    • Wann, L.S. et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. J. Am. Coll. Cardiol. 57, 1330-1337 (2011).
    • (2011) J. Am. Coll. Cardiol , vol.57 , pp. 1330-1337
    • Wann, L.S.1
  • 46
    • 84858595913 scopus 로고    scopus 로고
    • Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: Recommendations for stroke prevention and rate/rhythm control
    • Skanes, A.C. et al. Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: Recommendations for stroke prevention and rate/rhythm control. Can. J. Cardiol. 28, 125-136 (2012).
    • (2012) Can. J. Cardiol , vol.28 , pp. 125-136
    • Skanes, A.C.1
  • 49
    • 79958126202 scopus 로고    scopus 로고
    • Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: An analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY
    • Eikelboom, J.W. et al. Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: An analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY trial. Circulation 123, 2363-2372 (2011).
    • (2011) Trial Circulation , vol.123 , pp. 2363-2372
    • Eikelboom, J.W.1
  • 50
    • 0002306763 scopus 로고
    • Noncompliance with medication regimens and subsequent hospitalizations: A literature analysis and cost of hospitalization estimate
    • Sullivan, S.D., Kreling, D.H. & Hazlet, T.K. Noncompliance with medication regimens and subsequent hospitalizations: A literature analysis and cost of hospitalization estimate. J. Res. Pharmaceut. Econ. 2, 19-33 (1990).
    • (1990) J. Res. Pharmaceut. Econ , vol.2 , pp. 19-33
    • Sullivan, S.D.1    Kreling, D.H.2    Hazlet, T.K.3
  • 51
    • 0036719562 scopus 로고    scopus 로고
    • Patient adherence and medical treatment outcomes: A meta-analysis
    • DiMatteo, M.R., Giordani, P.J., Lepper, H.S. & Croghan, T.W. Patient adherence and medical treatment outcomes: A meta-analysis. Med. Care 40, 794-811 (2002).
    • (2002) Med. Care , vol.40 , pp. 794-811
    • DiMatteo, M.R.1    Giordani, P.J.2    Lepper, H.S.3    Croghan, T.W.4
  • 52
    • 0000120805 scopus 로고
    • Partial medication compliance: The enigma in poor medical outcomes
    • Cramer, J.A. Partial medication compliance: The enigma in poor medical outcomes. Am. J. Manag. Care 1, 167-74 (1995).
    • (1995) Am. J. Manag. Care , vol.1 , pp. 167-74
    • Cramer, J.A.1
  • 53
    • 0034871011 scopus 로고    scopus 로고
    • A systematic review of the associations between dose regimens and medication compliance
    • Claxton, A.J., Cramer, J. & Pierce, C. A systematic review of the associations between dose regimens and medication compliance. Clin. Ther. 23, 1296(2001).
    • (2001) Clin. Ther , vol.23 , pp. 1296
    • Claxton, A.J.1    Cramer, J.2    Pierce, C.3
  • 55
    • 77952737706 scopus 로고    scopus 로고
    • Drug and dietary interactions of the new and emerging oral anticoagulants
    • Walenga, J.M. & Adiguzel, C. Drug and dietary interactions of the new and emerging oral anticoagulants. Int. J. Clin. Pract. 64, 956-967 (2010).
    • (2010) Int. J. Clin. Pract , vol.64 , pp. 956-967
    • Walenga, J.M.1    Adiguzel, C.2
  • 57
    • 79958077792 scopus 로고    scopus 로고
    • Drug and dietary interactions of warfarin and novel oral anticoagulants: An update
    • Nutescu, E., Chuatrisorn, I. & Hellenbart, E. Drug and dietary interactions of warfarin and novel oral anticoagulants: An update. J. Thromb. Thrombolysis 31, 326-343 (2011).
    • (2011) J. Thromb. Thrombolysis , vol.31 , pp. 326-343
    • Nutescu, E.1    Chuatrisorn, I.2    Hellenbart, E.3
  • 58
    • 84862907587 scopus 로고    scopus 로고
    • Rivaroxaban in patients with a recent acute coronary syndrome
    • Mega, J.L. et al. Rivaroxaban in patients with a recent acute coronary syndrome. N. Engl. J. Med. 366, 9-19 (2012).
    • (2012) N. Engl. J. Med , vol.366 , pp. 9-19
    • Mega, J.L.1
  • 59
    • 79960955075 scopus 로고    scopus 로고
    • The use of dabigatran in elderly patients
    • Legrand, M. et al. The use of dabigatran in elderly patients. Arch. Intern. Med. 171, 1285-1286 (2011).
    • (2011) Arch. Intern. Med , vol.171 , pp. 1285-1286
    • Legrand, M.1
  • 62
    • 78149465761 scopus 로고    scopus 로고
    • Potential of activated prothrombin complex concentrate and activated factor VII to reverse the anticoagulant effects of rivaroxaban in primates
    • Gruber, A., Marzec, U.M., Buetehorn, U., Hanson, S. & Perzborn, E. Potential of activated prothrombin complex concentrate and activated factor VII to reverse the anticoagulant effects of rivaroxaban in primates. ASH Annual Meeting Abstracts 112, 3825 (2008).
    • (2008) ASH Annual Meeting Abstracts , vol.112 , pp. 3825
    • Gruber, A.1    Marzec, U.M.2    Buetehorn, U.3    Hanson, S.4    Perzborn, E.5
  • 63
    • 67849124919 scopus 로고    scopus 로고
    • Reversibility of the anticoagulant effect of high doses of the direct thrombin inhibitor dabigatran, by recombinant factor VIIa or active prothrombin complex concentrate
    • Abs 0370
    • van Ryn, J., Ruehl, D., Priepke, H., Hauel, N. & Wienen, W. Reversibility of the anticoagulant effect of high doses of the direct thrombin inhibitor dabigatran, by recombinant factor VIIa or active prothrombin complex concentrate. Haematologica 93 (suppl. 1), Abs. 0370 (2008).
    • (2008) Haematologica , vol.93 , Issue.SUPPL. 1
    • Van Ryn, J.1    Ruehl, D.2    Priepke, H.3    Hauel, N.4    Wienen, W.5
  • 64
    • 84856214360 scopus 로고    scopus 로고
    • Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran
    • Zhou, W. et al. Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran. Stroke. 42, 3594-3599 (2011).
    • (2011) Stroke , vol.42 , pp. 3594-3599
    • Zhou, W.1
  • 65
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg, E.S., Kamphuisen, P.W., Sijpkens, M.K., Meijers, J.C., Buller, H.R. & Levi, M. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects. Circulation 124, 1573-1579 (2011).
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3    Meijers, J.C.4    Buller, H.R.5    Levi, M.6
  • 66
    • 84864370719 scopus 로고    scopus 로고
    • Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers
    • Marlu, R., Hodaj, E., Paris, A., Albaladejo, P., Crackowski, J.L. & Pernod, G. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers. Thromb. Haemost. 108, 217-224 (2012).
    • (2012) Thromb. Haemost , vol.108 , pp. 217-224
    • Marlu, R.1    Hodaj, E.2    Paris, A.3    Albaladejo, P.4    Crackowski, J.L.5    Pernod, G.6
  • 67
    • 84857759555 scopus 로고    scopus 로고
    • Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding
    • Warkentin, T.E., Margetts, P., Connolly, S.J., Lamy, A., Ricci, C. & Eikelboom, J.W. Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood 119, 2172-2174 (2012).
    • (2012) Blood , vol.119 , pp. 2172-2174
    • Warkentin, T.E.1    Margetts, P.2    Connolly, S.J.3    Lamy, A.4    Ricci, C.5    Eikelboom, J.W.6
  • 68
    • 84860746568 scopus 로고    scopus 로고
    • Neurosurgical complications of direct thrombin inhibitors-catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran
    • Garber, S.T., Sivakumar, W. & Schmidt, R.H. Neurosurgical complications of direct thrombin inhibitors-catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran. J. Neurosurg. 116, 1093-1096 (2012).
    • (2012) J. Neurosurg , vol.116 , pp. 1093-1096
    • Garber, S.T.1    Sivakumar, W.2    Schmidt, R.H.3
  • 69
    • 84865856473 scopus 로고    scopus 로고
    • Reversing dabigatran with FEIBA in a patient with a transseptal perforation during cardiac ablation
    • Abst 867
    • Dager, W. & Roberts, A. Reversing dabigatran with FEIBA in a patient with a transseptal perforation during cardiac ablation. Crit Care Med 39 (suppl. 12), Abst. 867 (2011).
    • Crit Care Med , vol.39 , Issue.SUPPL. 12 , pp. 2011
    • Dager, W.1    Roberts, A.2
  • 70
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate - A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn, J. et al. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb. Haemost. 103, 1116-1127 (2010).
    • (2010) Thromb. Haemost , vol.103 , pp. 1116-1127
    • Van Ryn, J.1
  • 71
    • 34447522035 scopus 로고    scopus 로고
    • In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
    • Wienen, W., Stassen, J.M., Priepke, H., Ries, U.J. & Hauel, N. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate. Thromb. Haemost. 98, 155-162 (2007).
    • (2007) Thromb. Haemost , vol.98 , pp. 155-162
    • Wienen, W.1    Stassen, J.M.2    Priepke, H.3    Ries, U.J.4    Hauel, N.5
  • 72
    • 79958813704 scopus 로고    scopus 로고
    • Cost-effectiveness of dabigatran for stroke prophylaxis in atrial fibrillation
    • Shah, S.V. & Gage, B.F. Cost-effectiveness of dabigatran for stroke prophylaxis in atrial fibrillation. Circulation 123, 2562-2570 (2011).
    • (2011) Circulation , vol.123 , pp. 2562-2570
    • Shah, S.V.1    Gage, B.F.2
  • 73
    • 0344861847 scopus 로고    scopus 로고
    • Anticoagulation therapy for stroke prevention in atrial fibrillation: How well do randomized trials translate into clinical practice
    • Go, A.S. et al. Anticoagulation therapy for stroke prevention in atrial fibrillation: How well do randomized trials translate into clinical practice? JAMA 290, 2685-2692 (2003).
    • (2003) JAMA , vol.290 , pp. 2685-2692
    • Go, A.S.1
  • 74
    • 78650951581 scopus 로고    scopus 로고
    • A comparison of risk stratification schemes for stroke in 79,884 atrial fibrillation patients in general practice
    • Van Staa, T.P., Setakis, E., Di Tanna, G.L., Lane, D.A. & Lip, G.Y. A comparison of risk stratification schemes for stroke in 79,884 atrial fibrillation patients in general practice. J. Thromb. Haemost. 9, 39-48 (2011).
    • (2011) J. Thromb. Haemost , vol.9 , pp. 39-48
    • Van Staa, T.P.1    Setakis, E.2    Di Tanna, G.L.3    Lane, D.A.4    Lip, G.Y.5
  • 75
    • 26444498631 scopus 로고    scopus 로고
    • The role of P-glycoprotein and organic anion-transporting polypeptides in drug interactions
    • DuBuske, L.M. The role of P-glycoprotein and organic anion-transporting polypeptides in drug interactions. Drug Saf. 28, 789-801 (2005).
    • (2005) Drug Saf , vol.28 , pp. 789-801
    • DuBuske, L.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.