Sparing the larynx and esophageal inlet expedites feeding tube removal in patients with stage III-IV oropharyngeal squamous cell carcinoma treated with intensity-modulated radiotherapy

Laryngoscope

Volumn 122, Issue 12, 2012, Pages 2736-2742

  Amin, Neha ^a   Reddy, Krishna ^a   Westerly, David ^a   Raben, David ^a   Dewitt, Peter ^a   Chen, Changhu ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

intensity modulated radiotherapy; Larynx esophageal inlet sparing; oropharyngeal carcinoma

Indexed keywords

CARBOPLATIN; CETUXIMAB; PACLITAXEL;

ADULT; AGED; ARTICLE; BODY WEIGHT; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER STAGING; CARCINOMA; DISTANT METASTASIS FREE SURVIVAL; DYSPHAGIA; ESOPHAGUS; FEEDING APPARATUS; FEMALE; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LARYNX; MAJOR CLINICAL STUDY; MALE; NECK DISSECTION; ORGANS AT RISK; OROPHARYNX CANCER; OROPHARYNXL SQUAMOUS CELL CARCINOMA; OVERALL SURVIVAL; PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION FIELD; RETROSPECTIVE STUDY; SMOKING; SWALLOWING; TREATMENT DURATION; TUBE REMOVAL;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; DEGLUTITION DISORDERS; DEVICE REMOVAL; ESOPHAGUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LARYNX; MALE; MIDDLE AGED; NEOPLASM STAGING; ORGANS AT RISK; OROPHARYNGEAL NEOPLASMS; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES;

EID: 84871267516     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.23597     Document Type: Article

References (10)

1. Rosenthal DI, Lewin JS, Eisbruch A,. Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer. J Clin Oncol 2006; 24: 2636-2643.
2. Nguyen NP, Frank C, Moltz CC, et al. Impact of dysphagia on quality of life after treatment of head-and-neck cancer. Int J Radiat Oncol Biol Phys 2005; 61: 772-778.
3. Eisbruch A, Schwartz M, Rasch C, et al. Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT? Int J Radiat Oncol Biol Phys 2004; 60: 1425-1439.
4. Caglar HB, Tishler RB, Othus M, et al. Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2008; 72: 1110-1118.
5. Levendag PC, Teguh DN, Voet P, et al. Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship. Radiother Oncol 2007; 85: 64-73.
6. Caudell JJ, Schaner PE, Desmond RA, Meredith RF, Spencer SA, Bonner JA,. Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys 2010; 76: 403-409.
7. Teguh DN, Levendag PC, Noever I, et al. Treatment techniques and site considerations regarding dysphagia-related quality of life in cancer of the oropharynx and nasopharynx. Int J Radiat Oncol Biol Phys 2008; 72: 1119-1127.
8. Dirix P, Abbeel S, Vanstraelen B, Hermans R, Nuyts S,. Dysphagia after chemoradiotherapy for head-and-neck squamous cell carcinoma: dose-effect relationships for the swallowing structures. Int J Radiat Oncol Biol Phys 2009; 75: 385-392.
9. Feng FY, Kim HM, Lyden TH, et al. Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures. Int J Radiat Oncol Biol Phys 2007; 68: 1289-1298.
10. Feng FY, Kim HM, Lyden TH, et al. Intensity-modulated chemoradiotherapy aiming to reduce dysphagia in patients with oropharyngeal cancer: clinical and functional results. J Clin Oncol 2010; 28: 2732-2738.