Expression of fgf23 and αklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio

Nephrology Dialysis Transplantation

Volumn 27, Issue 12, 2012, Pages 4314-4322

  Mangos, Steve ^a   Amaral, Ansel P ^a   Faul, Christian ^a   Jüppner, Harald ^b   Reiser, Jochen ^a   Wolf, Myles ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

corpuscles of Stannius; FGF23; kidney; klotho; pronephros; zebrafish

Indexed keywords

ALPHA KLOTHO PROTEIN; FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; UNCLASSIFIED DRUG;

AKLOTHO GENE; AMINO ACID SEQUENCE; ANATOMICAL VARIATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; EMBRYO; ENDOCRINE GLAND; FGF23 GENE; FISH GENETICS; GENE; GENE ACTIVITY; GENE EXPRESSION PROFILING; GENE FUNCTION; LIVER; NEPHRON; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PANCREAS; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PRONEPHROS; ZEBRA FISH;

AGE FACTORS; ANIMALS; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; FIBROBLAST GROWTH FACTORS; GLUCURONIDASE; KIDNEY; ZEBRAFISH;

EID: 84871233875     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs335     Document Type: Article

References (32)

1. Wolf M. Forging forward with 10 burning questions on FGF23 in kidney disease. J Am Soc Nephrol 2010; 21: 1427-1435.
2. Shimada T, Hasegawa H, Yamazaki Y et al. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 2004; 19: 429-435.
3. Shimada T, Kakitani M, Yamazaki Y et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest 2004; 113: 561-568.
4. Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; 117: 4003-4008.
5. Riminucci M, Collins MT, Fedarko NS et al. FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting. J Clin Invest 2003; 112: 683-692.
6. Urakawa I, Yamazaki Y, Shimada T et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006; 444: 770-774.
7. Huang CL, Moe OW. Klotho: a novel regulator of calcium and phosphorus homeostasis. Pflugers Arch 2011; 462: 185-193.
8. Cha SK, Ortega B, Kurosu H et al. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci USA 2008; 105: 9805-9810.
9. Cha SK, Hu MC, Kurosu H et al. Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho. Mol Pharmacol 2009; 76: 38-46.
10. Lu P, Boros S, Chang Q et al. The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6. Nephrol Dial Transplant 2008; 23: 3397-3402.
11. Hu MC, Shi M, Zhang J et al. Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J 2010; 24: 3438-3450.
12. Kuro OM. Phosphate and klotho. Kidney Int Suppl 2011; S20-S23.
13. Farrow EG, Davis SI, Summers LJ et al. Initial FGF23-mediated signaling occurs in the distal convoluted tubule. J Am Soc Nephrol 2009; 20: 955-960.
14. Kuro-o M, Matsumura Y, Aizawa H et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997; 390: 45-51.
15. Westerfield M. The Zebrafish Book: A Guide for the Laboratory Use of the Zebrafish (Danio rerio), 5th edn. Eugene: University of Oregon Press, 2007.
16. Kimmel CB, Ballard WW, Kimmel SR et al. Stages of embryonic development of the zebrafish. Dev Dyn 1995; 203: 253-310.
17. Thisse C, Thisse B. High-resolution in situ hybridization to wholemount zebrafish embryos. Nat Protoc 2008; 3: 59-69.
18. Lametschwandtner A. Microvascularization of corpuscles of Stannius in teleost fishes. Microsc Res Tech 1995; 32: 104-111.
19. Wagner GF, Dimattia GE. The stanniocalcin family of proteins. J Exp Zool A Comp Exp Biol 2006; 305: 769-780.
20. Olsen HS, Cepeda MA, Zhang QQ et al. Human stanniocalcin: a possible hormonal regulator of mineral metabolism. Proc Natl Acad Sci USA 1996; 93: 1792-1796.
21. Thisse B, Thisse C. Fast Release Clones: A High Throughput Expression Analysis. ZFIN: The Zebrafish Information Network, 2004, http://zfin.org/cgi- bin/webdriver?MIval=aa-pubview2. apg&OID=ZDB-PUB-040907-1
22. Sugano Y, Lardelli M. Identification and expression analysis of the zebrafish orthologue of Klotho. Dev Genes Evol 2011; 221: 179-186.
23. Li SA, Watanabe M, Yamada H et al. Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice. Cell Struct Funct 2004; 29: 91-99.
24. Ohyama Y, Kurabayashi M, Masuda H et al. Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress. Biochem Biophys Res Commun 1998; 251: 920-925.
25. Kramer-Zucker AG, Wiessner S, Jensen AM et al. Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes. Dev Biol 2005; 285: 316-329.
26. Itoh N, Konishi M. The zebrafish fgf family. Zebrafish 2007; 4: 179-186.
27. Vascotto SG, Beckham Y, Kelly GM. The zebrafish's swim to fame as an experimental model in biology. Biochem Cell Biol 1997; 75: 479-485.
28. Elizondo MR, Budi EH, Parichy DM. trpm7 regulation of in vivo cation homeostasis and kidney function involves stanniocalcin 1 and fgf23. Endocrinology 2010; 151: 5700-5709.
29. Hayashi Y, Okino N, Kakuta Y et al. Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase. J Biol Chem 2007; 282: 30889-30900.
30. Kurosu H, Ogawa Y, Miyoshi M et al. Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 2006; 281: 6120-6123.
31. Wolf M. Update on fibroblast growth factor 23 in chronic kidney disease. Kidney Int 2012; May 23. doi: 10.1038/ki.2012.176. [Epub ahead of print].
32. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22: 4673-4680.