Autophagy and role in asthma

Current Opinion in Pulmonary Medicine

Volumn 19, Issue 1, 2013, Pages 30-35

  Jyothula, Soma S S K ^a   Eissa, N Tony ^b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

asthma; autophagy; common respiratory viruses; genetic polymorphism

Indexed keywords

ASTHMA; AUTOPHAGY; CELL FUNCTION; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; HUMAN; INFLAMMATION; NONHUMAN; RESPIRATORY VIRUS; REVIEW; TH2 CELL; VIRAL RESPIRATORY TRACT INFECTION; VIRUS REPLICATION;

ASTHMA; AUTOPHAGY; DISEASE SUSCEPTIBILITY; HUMANS; IMMUNITY; MICROTUBULE-ASSOCIATED PROTEINS; POLYMORPHISM, GENETIC; RESPIRATORY TRACT INFECTIONS;

EID: 84871229031     PISSN: 10705287     EISSN: 15316971     Source Type: Journal    
DOI: 10.1097/MCP.0b013e32835b1150     Document Type: Review

References (17)

1. Centers for Disease Control and Prevention (CDC). Vital signs: asthma prevalence, disease characteristics, and self-management education: United States, 2001-2009. MMWR Morb Mortal Wkly Rep 2011; 60:547-552.
2. Lin K, Li J, Finn P. Emerging pathways in asthma: innate and adaptive interactions. Biochim Biophys Acta 2011; 1810:1052-1058.
3. Xu Y, Eissa T. Autophagy in Innate and adaptive immunity. Proc Am Thorac Soc 2010; 7:22-28.
4. Zhou Z, Jiang X, Liu D, et al. Autophagy is involved in influenza A virus replication. Autophagy 2009; 5:321-328.
5. Gannagé M, Dormann D, Albrecht R, et al. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009; 6:367-380.
6. Jounai N, Takeshita F, Kobiyama K, et al. The Atg5-Atg12 conjugate associates with innate antiviral immune responses. Proc Natl Acad Sci USA 2007; 104:14050-14055.
7. Bartlett N, McLean G, Chang Y, Johnston S. Genetics and epidemiology: asthma and infection. Curr Opin Allergy Clin Immunol 2009; 9:395-400.
8. Klein K, Jackson W. Human rhinovirus 2 induces the autophagic pathway and replicates more efficiently in autophagic cells. J Virol 2011; 85:9651-9654.
9. Morris S, Swanson M, Lieberman A, et al. Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses. J Immunol 2011; 187:3953-3961.
10. Moore W, Pascual R. Update in asthma 2009. Am J Respir Crit Care Med 2010; 81:1181-1187.
11. Sun Y, Li C, Shu Y, et al. Inhibition of autophagy ameliorates acute lung injury caused by avian influenza A H5N1 infection. Sci Signal 2012; 5:16.
12. Prentice E, Jerome W, Yoshimori T, et al. Coronavirus replication complex formation utilizes components of cellular autophagy. J Biol Chem 2004; 279:10136-10141.
13. Zhao Z, Thackray L, Miller B, et al. Coronavirus replication does not require the autophagy gene ATG5. Autophagy 2007; 3:581-585.
14. Cottam E, Maier H, Manifava M, et al. Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome inter mediate. Autophagy 2011; 7:1335-1347.
15. Piya S, White E, Klein S, et al. The E1B19K oncoprotein complexes with beclin 1 to regulate autophagy in adenovirus-infected cells. PLoS ONE 2011; 6:e29467.
16. Poon AH, Chouiali F, Tse SM, et al. Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol 2012; 129:569-571.
17. Martin L, Gupta J, Jyothula S, et al. Functional variant in the autophagy-related 5 gene promoter is associated with childhood asthma. PLoS ONE 2012; 7:e33454.