Epimacular brachytherapy for the treatment of retinal angiomatous proliferation

Retinal Cases and Brief Reports

Volumn 6, Issue 4, 2012, Pages 353-357

  Petrarca, Robert ^a   Nau, Jeffrey ^b   Dugel, Pravin U ^c   Jackson, Timothy L ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b NeoVista   (United States)

^c RETINAL CONSULTANTS OF ARIZONA   (United States)

Author keywords

Epimacular brachytherapy; Neovascular age related macular degeneration; Radiation therapy; Retinal angiomatous proliferation (RAP)

Indexed keywords

EID: 84871186611     PISSN: 19351089     EISSN: 19371578     Source Type: Journal    
DOI: 10.1097/ICB.0b013e31823c12a3     Document Type: Article

References (15)

1. Hartnett ME, Weiter JJ, Staurenghi G, Elsner AE. Deep retinal vascular anomalous complexes in advanced age-related mac-ular degeneration. Ophthalmology 1996;103:2042-2053.
2. Yannuzzi LA, Negrao S, Iida T, et al. Retinal angiomatous proliferation in age-related macular degeneration. Retina 2001;21:416-434.
3. Viola F, Massacesi A, Orzalesi N, et al. Retinal angiomatous proliferation: natural history and progression of visual loss. Retina 2009;29:732-739.
4. Matsumoto H, Sato T, Kishi S. Tomographic features of intraretinal neovascularization in retinal angiomatous proliferation. Retina 2010;30:425-430.
5. Yannuzzi LA, Freund KB, Takahashi BS. Review of retinal angiomatous proliferation or type 3 neovascularization. Retina 2008;28:375-384.
6. Querques G, Atmani K, Berboucha E, et al. Angiographic analysis of retinal-choroidal anastomosis by confocal scanning laser ophthalmoscopy technology and corresponding (eye-tracked) spectral-domain optical coherence tomography. Retina 2010;30:222-234.
7. Freund KB, Zweifel SA, Engelbert M. Do we need a new classification for choroidal neovascularization in age-related macular degeneration? Retina 2010;30:1333-1349.
8. Freund KB, Ho I, Barbazetb I, et al. Type 3 neovascularization: the expanded spectrum of retinal angiomatous proliferation. Retina 2008;28:201-211.
9. Hemeida TS, Keane PA, Dustin L, et al. Long-term visual and anatomical outcomes following anti-VEGF monother-apy for retinal angiomatous proliferation. Br J Ophthalmol 2010;94:701-705.
10. Ávila MP, Farah ME, Santos A, et al. Twelve-month short-term safety and visual-acuity results from a multicentre prospective study of epiretinal strontium-90 brachytherapy with bevacizu-mab for the treatment of subfoveal choroidal neovascularisation secondary to age-related macular degeneration. Br J Ophthalmol 2009;93:305-309.
11. Ávila MP, Farah ME, Santos A, et al. Twelve-month safety and visual acuity results from a feasibility study of intraocular, epiretinal radiation therapy for the treatment of subfoveal CNV secondary to AMD. Retina 2009;29:157-169.
12. Hall EJ, Marchese M, Rubin J, et al. Low dose rate irradiation. Front Radiat Ther Oncol 1988;22:19-29.
13. Bischof M, Abdollahi A, Gong P, et al. Triple combination of irradiation, chemotherapy (pemetrexed), and VEGFR inhibition (SU5416) in human endothelial and tumor cells. Int J Radiat Oncol Biol Phys 2004;60:1220-1232.
14. Timke C, Zieher H, Roth A, et al. Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy. Clin Cancer Res 2008;14:2210-2219.
15. Saunders WB, Bohnsack BL, Faske JB, et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol 2006;175:179-191.