Poloxamine micellar solubilization of α-tocopherol for topical ocular treatment

Colloids and Surfaces B: Biointerfaces

Volumn 103, Issue , 2013, Pages 550-557

  Ribeiro, Andreza ^a   Sandez Macho, Isabel ^a   Casas, Matilde ^a   Alvarez Pérez, Susana ^a   Alvarez Lorenzo, Carmen ^a   Concheiro, Angel ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Tocopherol; A isotherm; Cataracts; Ocular drug delivery; Polymeric micelles; Tetronic 1107

Indexed keywords

AIR WATER INTERFACES; ANTIOXIDANT ACTIVITIES; AQUEOUS MEDIUM; CATARACTS; CRITICAL MICELLAR CONCENTRATIONS; DIFFUSION CELLS; DRY EYE; ELECTRONIC MICROSCOPY; EYE-DROPS; FAVORABLE INTERACTIONS; FREE FLOWING; IN-SITU-GELLING; MICELLAR SOLUBILIZATION; MICELLAR SYSTEMS; OCULAR DRUG DELIVERY; OCULAR PATHOLOGY; OPHTHALMIC DELIVERY; POLOXAMINES; POLYMERIC MICELLE; RHEOLOGICAL PROPERTY; SHARP INCREASE; SUSTAINED RELEASE; TETRONIC; VISCO-ELASTIC PARAMETERS; VITAMIN-E;

BLOCK COPOLYMERS; DRUG DELIVERY; DRUG PRODUCTS; DYES; DYNAMIC LIGHT SCATTERING; ISOTHERMS; LOADING; POLYETHYLENE OXIDES; POLYMER BLENDS; POLYMERS; PROPYLENE; SODIUM CHLORIDE; SOLUBILITY;

MICELLES;

ALPHA TOCOPHEROL; COPOLYMER; MACROGOL; POLY(PROPYLENE OXIDE); PROPYLENE OXIDE; TETRONIC 1107; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; HIGH TEMPERATURE; ISOTHERM; LACRIMAL FLUID; LIGHT SCATTERING; LOW TEMPERATURE; MICELLE; PRIORITY JOURNAL; SOLUBILIZATION; STORAGE TEMPERATURE; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; VISCOELASTICITY;

ADMINISTRATION, OPHTHALMIC; ADMINISTRATION, TOPICAL; ALPHA-TOCOPHEROL; DIFFUSION; ELASTIC MODULUS; LIGHT; MICELLES; PHASE TRANSITION; POLYETHYLENE GLYCOLS; SCATTERING, RADIATION; SOLUBILITY; TEMPERATURE; VISCOSITY; WATER;

EID: 84871134897     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2012.10.055     Document Type: Article

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