Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy.

Science translational medicine

Volumn 4, Issue 164, 2012, Pages

  Kendall, Genevieve C ^a   Mokhonova, Ekaterina I ^b   Moran, Miriana ^b   Sejbuk, Natalia E ^b   Wang, Derek W ^b   Silva, Oscar ^b   Wang, Richard T ^b   Martinez, Leonel ^b   Lu, Q L ^b   Damoiseaux, Robert ^b   Spencer, Melissa J ^b   Nelson, Stanley F ^b   Miceli, M Carrie ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DANTROLENE; DYSTROPHIN; RYANODINE RECEPTOR;

ANIMAL; ANIMAL MUSCULAR DYSTROPHY; ARTICLE; C57BL MOUSE; CELL LINE; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; DUCHENNE MUSCULAR DYSTROPHY; EXON; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; SARCOLEMMA; SKELETAL MUSCLE;

ANIMALS; CELL LINE; DANTROLENE; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DYSTROPHIN; EXONS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED C57BL; MUSCLE FIBERS, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; MUSCULAR DYSTROPHY, DUCHENNE; OLIGONUCLEOTIDES, ANTISENSE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOLEMMA;

EID: 84871061937     PISSN: None     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3005054     Document Type: Article

References (0)