Synthesis and antiplasmodial activity of some 1-azabenzanthrone derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 327-329

  Castro Castillo, Vicente ^a   Suárez Rozas, Cristian ^a   Pabón, Adriana ^b   Pérez, Edwin G ^c   Cassels, Bruce K ^d   Blair, Silvia ^b  

^a UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACIÓN   (Chile)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^d UNIVERSITY OF CHILE   (Chile)

Author keywords

1 Azabenzanthrones; Antimalarial; Chloroquine resistant Plasmodium falciparum; Selectivity

Indexed keywords

1 AZABENZANTHRONE; 3 BROMO 1 AZABENZANTHRONE; 3 BROMO 5 METHOXY 1 AZABENZANTHRONE; 4 BROMO 5 METHOXY 1 AZABENZANTHRONE; 5 METHOXY 1 AZABENZANTHRONE; 5 METHOXY 2,3 DIHYDRO 1 AZABENZANTHRONE; 5 METHOXY 4 AMINO 1 AZABENZANTHRONE; 5 METHOXY 4 NITRO 1 AZABENZANTHRONE; 5 METHOXY 6 AMINO 1 AZABENZANTHRONE; 5 METHOXY 6 HYDROXY 1 AZABENZANTHRONE; 5 METHOXY 6 NITRO 1 AZABENZANTHRONE; 5,6 DIMETHOXY 1 AZABENZANTHRONE; ANTIMALARIAL AGENT; CHLOROQUINE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CYTOTOXICITY; FIBROBLAST; HUMAN; IN VITRO STUDY; PARASITE; PLASMODIUM FALCIPARUM; SYNTHESIS;

ANTIMALARIALS; AZA COMPOUNDS; BENZ(A)ANTHRACENES; CELL LINE; CELL SURVIVAL; CHLOROQUINE; DRUG RESISTANCE; HUMANS; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 84871015584     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.092     Document Type: Article

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