Dynorphin A 1-17 biotransformation in inflamed tissue, serum and trypsin solution analysed by liquid chromatography-tandem mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 404, Issue 10, 2012, Pages 3111-3121

  Morgan, M ^a   Herath, H M D R ^a   Cabot, P J ^a   Shaw, P N ^a   Hewavitharana, A K ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Dynorphin; Fragments; Inflamed tissue; LC MS MS; Metabolism

Indexed keywords

DYNORPHIN; FRAGMENTS; INCUBATION PERIODS; ION CURRENTS; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; NEUROPEPTIDES; PRIMARY FRAGMENTS; RAT SERUM; SECONDARY BREAKDOWN;

BIOCONVERSION; BODY FLUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHYSIOLOGY; RATS; TISSUE;

METABOLISM;

DYNORPHIN; TRYPSIN;

ANIMAL; ARTICLE; BLOOD; HINDLIMB; INFLAMMATION; LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; RAT; SERUM; SWINE; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; DYNORPHINS; HINDLIMB; INFLAMMATION; RATS; SERUM; SWINE; TANDEM MASS SPECTROMETRY; TRYPSIN;

RATTUS;

EID: 84870938420     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-6406-8     Document Type: Article

References (29)

1. Day R, Lazure C, Basak A, Boudreault A, Limperis P, Dong W, Lindberg I (1998) J Biol Chem 273:829-836
2. Inan S, Cowan A (2006) Pharmacol Biochem Behav 85:39-43
3. Tiseo PJ, Geller EB, Adler MW (1988) J Pharmacol Exp Ther 246:449-453
4. Tsushima H, Mori M, Matsuda T (1993) Jpn J Pharmacol 63:461-468
5. Narita M, Kishimoto Y, Ise Y, Yajima Y, Misawa K, Suzuki T (2005) Neuropsychopharmacology 30:111-118
6. Chou JZ, Chait BT, Wang R, Kreek MJ (1996) Peptides 17:983- 990
7. Klintenberg R, Andren PE (2005) J Mass Spectrom 40:261-270
8. Muller S, Hochhaus G (1995) Pharm Res 12:1165-1170
9. Reed B, Zhang Y, Chait BT, Kreek MJ (2003) J Neurochem 86:815-823
10. Ahmed MS, Cemerikic B, Agbas A (1992) Life Sci 50:83-97
11. Cabot PJ, Carter L, Schafer M, Stein C (2001) Pain 93:207-212
12. Sidhu P, Shojaee AF, Andrews M, Lees P (2003) Res Vet Sci 74:67-77
13. Weiss C, Kaplan A, Larson CE (1938) J Biol Chem 125:247-257
14. Nissen JB, Iversen L, Kragballe K (1995) Br J Dermatol 133:742-749
15. Berman Y, Ageyeva L, Veksler B, Wood D, Devi LA (1999) J Biochem 125:641-647
16. Auld DS, Vallee BL (1970) Biochemistry 9:4352-4359
17. Polgar L (1991) Eur J Biochem 197:441-447
18. Herath HM, Cabot PJ, Shaw PN, Hewavitharana AK (2012) Anal Bioanal Chem 402:2089-2100
19. Chavkin C, Goldstein A (1981) Proc Natl Acad Sci U S A 78:6543-6547
20. Svensson CI, Hua XY, Powell HC, Lai J, Porreca F, Yaksh TL (2005) Neuropeptides 39:485-494
21. Ichinose M, Asai M, Sawada M (1995) J Neuroimmunol 60:37-43
22. Wei ET, Thomas HA, Gjerde EA, Reed RK, Burov SV, Korolkov VI, Glynskaya OV, Dorosh MY, Vlasov GP (1998) Peptides 19:767-775
23. Blanchard J (1981) J Chromatogr 226:455-460
24. Karol MD (1990) Biopharm Drug Dispos 11:179-181
25. Goldstein A, Fischli W, Lowney LI, Hunkapiller M, Hood L (1981) Proc Natl Acad Sci U S A 78:7219-7223
26. Yu J, Butelman ER, Woods JH, Chait BT, Kreek MJ (1996) J Pharmacol Exp Ther 279:507-514
27. Benuck M, Berg MJ, Marks N (1984) Neurochem Res 9:733-749
28. Silberring J, Castello ME, Nyberg F (1992) J Biol Chem 267:21324-21328
29. Thomas HA, Wei ET (1995) Peptides 16:547-550