NPY and NPY receptors in airway structural and inflammatory cells in allergic asthma

Experimental and Molecular Pathology

Volumn 94, Issue 1, 2013, Pages 45-50

  Makinde, Toluwalope O ^a   Steininger, Robert ^a   Agrawal, Devendra K ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Allergic asthma; Antigen presenting cells (APCs); Macrophage; NPY receptor Y1; Transforming growth factor beta (TGF )

Indexed keywords

ALPHA ACTIN; EPITHELIAL CELL ADHESION MOLECULE; INTERLEUKIN 4; METHACHOLINE; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

AIRWAY REMODELING; ALLERGIC ASTHMA; ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; INFLAMMATORY CELL; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; SMOOTH MUSCLE FIBER;

ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; ENZYME ACTIVATION; INFLAMMATION; INTERLEUKIN-4; LUNG; MACROPHAGES; MICE; MICE, INBRED BALB C; NEUROPEPTIDE Y; OVALBUMIN; RECEPTORS, NEUROPEPTIDE Y; RESPIRATORY SYSTEM; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

MUS;

EID: 84870930776     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2012.05.009     Document Type: Article

References (21)

1. Bedoui S., Miyake S., Straub R.H., von Horsten S., Yamamura T. More sympathy for autoimmunity with neuropeptide Y?. Trends in Immunology 2004, 25:508-512.
2. El Karim I.A., Linden G.J., Orr D.F., Lundy F.T. Antimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites. Journal of Neuroimmunology 2008, 200:11-16.
3. Ericsson A., Hemsen A., Lundberg J.M., Persson H. Detection of neuropeptide Y-like immunoreactivity and messenger RNA in rat platelets: the effects of vinblastine, reserpine, and dexamethasone on NPY expression in blood cells. Experimental Cell Research 1991, 192:604-611.
4. Ferreira R., Xapelli S., Santos T., Silva A.P., Cristovao A., Cortes L., Malva J.O. Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia. The Journal of Biological Chemistry 2010, 285:41921-41934.
5. Jacob H.J., Pettersson A., Wilson D., Mao Y., Lernmark A., Lander E.S. Genetic dissection of autoimmune type I diabetes in the BB rat. Nature Genetics 1992, 2:56-60.
6. Kawamura N., Tamura H., Obana S., Wenner M., Ishikawa T., Nakata A., Yamamoto H. Differential effects of neuropeptides on cytokine production by mouse helper T cell subsets. Neuroimmunomodulation 1998, 5:9-15.
7. Macia L., Rao P.T., Wheway J., Sierro F., Mackay F., Herzog H. Y1 signalling has a critical role in allergic airway inflammation. Immunology and Cell Biology 2011, 89:882-888.
8. Michel M.C., Beck-Sickinger A., Cox H., Doods H.N., Herzog H., Larhammar D., Quirion R., Schwartz T., Westfall T. XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacological Reviews 1998, 50:143-150.
9. Musso R., Grilli M., Oberto A., Gamalero S.R., Eva C. Regulation of mouse neuropeptide Y Y1 receptor gene transcription: a potential role for nuclear factor-kappa B/Rel proteins. Molecular Pharmacology 1997, 51:27-35.
10. Myers A.K., Farhat M.Y., Vaz C.A., Keiser H.R., Zukowska-Grojec Z. Release of immunoreactive-neuropeptide by rat platelets. Biochemical and Biophysical Research Communications 1988, 155:118-122.
11. Myers A.K., Torres Duarte A.P., Zukowska-Grojec Z. Immunoreactive neuropeptide Y (NPY) in plasma and platelets of rat and mouse strains and human volunteers. Regulatory Peptides 1993, 47:239-245.
12. Nave H., Bedoui S., Moenter F., Steffens J., Felies M., Gebhardt T., Straub R.H., Pabst R., Dimitrijevic M., Stanojevic S., von Horsten S. Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y2 receptor activation. Journal of Neuroimmunology 2004, 155:1-12.
13. Ogawa T., Kitamura K., Kawamoto M., Eto T., Tanaka K. Increased immunoreactive neuropeptide Y in platelets of spontaneously hypertensive rats (SHR). Biochemical and Biophysical Research Communications 1989, 165:1399-1405.
14. Pravenec M., Zidek V., Simakova M., Kren V., Krenova D., Horky K., Jachymova M., Mikova B., Kazdova L., Aitman T.J., Churchill P.C., Webb R.C., Hingarh N.H., Yang Y., Wang J.M., Lezin E.M., Kurtz T.W. Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension. The Journal of Clinical Investigation 1999, 103:1651-1657.
15. Romano T.A., Felten S.Y., Felten D.L., Olschowka J.A. Neuropeptide-Y innervation of the rat spleen: another potential immunomodulatory neuropeptide. Brain, Behavior, and Immunity 1991, 5:116-131.
16. Schwarz H., Villiger P.M., von Kempis J., Lotz M. Neuropeptide Y is an inducible gene in the human immune system. Journal of Neuroimmunology 1994, 51:53-61.
17. Soder O., Hellstrom P.M. Neuropeptide regulation of human thymocyte, guinea pig T lymphocyte and rat B lymphocyte mitogenesis. International Archives of Allergy and Applied Immunology 1987, 84:205-211.
18. Sung C.P., Arleth A.J., Feuerstein G.Z. Neuropeptide Y upregulates the adhesiveness of human endothelial cells for leukocytes. Circulation Research 1991, 68:314-318.
19. Tatemoto K., Carlquist M., Mutt V. Neuropeptide Y-a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 1982, 296:659-660.
20. Wheway J., Mackay C.R., Newton R.A., Sainsbury A., Boey D., Herzog H., Mackay F. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. The Journal of Experimental Medicine 2005, 202:1527-1538.
21. Wheway J., Herzog H., Mackay F. The Y1 receptor for NPY: a key modulator of the adaptive immune system. Peptides 2007, 28:453-458.