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Volumn 912, Issue , 2013, Pages 16-23
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Development and validation of a sensitive liquid chromatography/tandem mass spectrometry method for the determination of raddeanin A in rat plasma and its application to a pharmacokinetic study
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Author keywords
Absolute bioavailability; LC MS MS; Pharmacokinetics; Raddeanin A
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Indexed keywords
ABSOLUTE BIOAVAILABILITY;
AMMONIUM ACETATE;
CHROMATOGRAPHIC SEPARATIONS;
CONCENTRATION RANGES;
EXTRACTION RECOVERY;
INTRAVENOUS ADMINISTRATION;
LC-ESI-MS/MS;
LC-MS/MS;
LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY;
MATRIX EFFECTS;
MOBILE PHASE;
MULTIPLE-REACTION MONITORING MODES;
PHARMACOKINETIC PROFILES;
PHARMACOKINETIC STUDIES;
RADDEANIN A;
RAT PLASMA;
RELATIVE ERRORS;
TANDEM MASS SPECTROMETRY;
TRIPLE QUADRUPOLE;
VALIDATED METHODS;
ACETONITRILE;
AMMONIUM COMPOUNDS;
BIOCHEMISTRY;
CHROMATOGRAPHY;
FORMIC ACID;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
METHANOL;
PHARMACOKINETICS;
BODY FLUIDS;
ACETONITRILE;
AMMONIUM ACETATE;
FORMIC ACID;
HERBACEOUS AGENT;
METHANOL;
RADDEANIN A;
UNCLASSIFIED DRUG;
ACCURACY;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
DRUG BIOAVAILABILITY;
DRUG CLEARANCE;
DRUG DISTRIBUTION;
DRUG HALF LIFE;
DRUG STABILITY;
FEMALE;
IONIZATION;
LIMIT OF QUANTITATION;
LIQUID CHROMATOGRAPHY;
MALE;
MAXIMUM PLASMA CONCENTRATION;
MEAN RESIDENCE TIME;
NONHUMAN;
PRECIPITATION;
PRIORITY JOURNAL;
RAT;
TANDEM MASS SPECTROMETRY;
TIME TO MAXIMUM PLASMA CONCENTRATION;
VALIDATION STUDY;
ANEMONE;
ANIMALS;
CHROMATOGRAPHY, LIQUID;
DRUGS, CHINESE HERBAL;
FEMALE;
MALE;
MOLECULAR STRUCTURE;
RATS;
RATS, SPRAGUE-DAWLEY;
TANDEM MASS SPECTROMETRY;
RATTUS;
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EID: 84870924590
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2012.09.038 Document Type: Article |
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Times cited : (18)
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References (11)
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