Generation of human bronchial epithelial cell lines expressing inactive mutants of GALNT3

Journal of Veterinary Medical Science

Volumn 74, Issue 11, 2012, Pages 1493-1496

  Nakamura, Shoko ^a,b   Horie, Masayuki ^a,c   Fujino, Kan ^a   Matsumoto, Yusuke ^a   Honda, Tomoyuki ^a   Tomonaga, Keizo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

GALNT3; Mucin; Respiratory viruses

Indexed keywords

MUCIN; N ACETYLGALACTOSAMINYLTRANSFERASE; POLYPEPTIDE N ACETYLGALACTOSAMINYLTRANSFERASE; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE;

CELL LINE; CYTOLOGY; GENE STRUCTURE; GENETICS; GLYCOSYLATION; HUMAN; METABOLISM; MISSENSE MUTATION; MUTAGENESIS; NOTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT MUCOSA; VIROLOGY;

CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE COMPONENTS; GLYCOSYLATION; HUMANS; MUCINS; MUTAGENESIS; MUTATION, MISSENSE; N-ACETYLGALACTOSAMINYLTRANSFERASES; RESPIRATORY MUCOSA; RESPIRATORY TRACT INFECTIONS;

EID: 84870923344     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.12-0199     Document Type: Note

References (18)

1. Brockhausen, I., Dowler, T. and Paulsen, H. 2009. Site directed processing: role of amino acid sequences and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2. Biochim. Biophys. Acta 1790: 1244-1257. [Medline] [CrossRef]
2. Excoffon, K. J., Gansemer, N. D., Mobily, M. E., Karp, P. H., Parekh, K. R. and Zabner, J. 2010. Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia. PLoS ONE 5: e9909. [Medline] [Cross-Ref]
3. Gu, C., Oyama, T., Osaki, T., Li, J., Takenoyama, M., Izumi, H., Sugio, K., Kohno, K. and Yasumoto, K. 2004. Low expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in lung adenocarcinoma: impact on poor prognosis and early recurrence. Br. J. Cancer 90: 436-442. [Medline] [CrossRef]
4. Hagen, F. K., Hazes, B., Raffo, R. and Tabak, L. A. 1999. Structure-function analysis of the UDP-N-acetyl-Dgalactosamine: polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold. J. Biol. Chem. 274: 6797-6803. [Medline] [CrossRef]
5. Hanisch, F. G., Müller, S., Hassan, H., Clausen, H., Zachara, N., Gooley, A. A., Paulsen, H., Alving, K. and Peter-Katalinic, J. 1999. Dynamic epigenetic regulation of initial O-glycosylation by UDP-N-acetylgalactosamine:peptide N-acetylgalactosaminyltransferases. Site-specific glycosylation of MUC1 repeat peptide influences the substrate qualities at adjacent or distant Ser/Thr positions. J. Biol. Chem. 274: 9946-9954. [Medline] [CrossRef]
6. Ioannidis, I., McNally, B., Willette, M., Peeples, M. E., Chaussabel, D., Durbin, J. E., Ramilo, O., Mejias, A. and Flaño, E. 2012. Plasticity and virus specificity of the airway epithelial cell immune response during respiratory viral infection. J. Virol. 86: 5422-5436. [Medline] [CrossRef]
7. Kato, K., Jeanneau, C., Tarp, M. A., Benet-Pagès, A., Lorenz-Depiereux, B., Bennett, E. P., Mandel, U., Strom, T. M. and Clausen, H. 2006. Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation. J. Biol. Chem. 281: 18370-18377. [Medline] [CrossRef]
8. Matrosovich, M. N., Matrosovich, T. Y., Gray, T., Roberts, N. A. and Klenk, H. D. 2004. Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium. J. Virol. 78: 12665-12667. [Medline] [CrossRef]
9. Miller, A. L., Strieter, R. M., Gruber, A. D., Ho, S. B. and Lukacs, N. W. 2003. CXCR2 regulates respiratory syncytial virusinduced airway hyperreactivity and mucus overproduction. J. Immunol. 170: 3348-3356. [Medline]
10. Nakamura-Tsuruta, S., Kominami, J., Kuno, A. and Hirabayashi, J. 2006. Evidence that Agaricus bisporus agglutinin (ABA) has dual sugar-binding specificity. Biochem. Biophys. Res. Commun. 347: 215-220. [Medline] [CrossRef]
11. Röttger, S., White, J., Wandall, H. H., Olivo, J. C., Stark, A., Bennett, E. P., Whitehouse, C., Berger, E. G., Clausen, H. and Nilsson, T. 1998. Localization of three human polypeptide Gal-NAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus. J. Cell Sci. 111: 45-60. [Medline]
12. Rudd, B. D., Smit, J. J., Flavell, R. A., Alexopoulou, L., Schaller, M. A., Gruber, A., Berlin, A. A. and Lukacs, N. W. 2006. Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. J. Immunol. 176: 1937-1942. [Medline]
13. Sabbah, A. and Bose, S. 2009. Retinoic acid inducible gene I activates innate antiviral response against human parainfluenza virus type 3. Virol. J. 6: 200. [Medline] [CrossRef]
14. Sanders, C. J., Doherty, P. C. and Thomas, P. G. 2011. Respiratory epithelial cells in innate immunity to influenza virus infection. Cell Tissue Res. 343: 13-21. [Medline] [CrossRef]
15. Tarp, M. A. and Clausen, H. 2008. Mucin-type O-glycosylation and its potential use in drug and vaccine development. Biochim. Biophys. Acta 1780: 546-563. [Medline] [CrossRef]
16. Wandall, H. H., Hassan, H., Mirgorodskaya, E., Kristensen, A. K., Roepstorff, P., Bennett, E. P., Nielsen, P. A., Hollingsworth, M. A., Burchell, J., Taylor-Papadimitriou, J. and Clausen, H. 1997. Substrate specificities of three members of the human UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1,-T2, and-T3. J. Biol. Chem. 272: 23503-23514. [Medline] [CrossRef]
17. Wragg, S., Hagen, F. K. and Tabak, L. A. 1997. Identification of essential histidine residues in UDP-N-acetyl-Dgalactosamine: polypeptide N-acetylgalactosaminyltransferase-T1. Biochem. J. 328: 193-197. [Medline]
18. Wu, W., Punt, J. A., Granger, L., Sharrow, S. O. and Kearse, K. P. 1997. Developmentally regulated expression of peanut agglutinin (PNA)-specific glycans on murine thymocytes. Glycobiology 7: 349-356. [Medline] [CrossRef]