Effectiveness of non-surgical treatment to reduce IL-18 levels in the gingival crevicular fluid of patients with periodontal disease

Brazilian Dental Journal

Volumn 23, Issue 4, 2012, Pages 428-432

  de Campos, Bernardo Oliveira ^a   Fischer, Ricardo Guimarães ^a   Gustafsson, Anders ^b   Figueredo, Carlos Marcelo da Silva ^a,b  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Interleukin 18; Periodontal treatment; Periodontitis

Indexed keywords

INTERLEUKIN 18;

ADULT; ARTICLE; CHRONIC PERIODONTITIS; EDUCATION; FOLLOW UP; GINGIVITIS; HUMAN; IMMUNOLOGY; METHODOLOGY; MIDDLE AGED; MOUTH HYGIENE; PERIODONTAL DISEASE; PERIODONTAL POCKET; PERIODONTICS; PREVENTIVE DENTISTRY; TOOTH PLAQUE;

ADULT; CHRONIC PERIODONTITIS; DENTAL PLAQUE INDEX; DENTAL SCALING; FOLLOW-UP STUDIES; GINGIVAL CREVICULAR FLUID; GINGIVITIS; HUMANS; INTERLEUKIN-18; MIDDLE AGED; ORAL HYGIENE; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PERIODONTAL POCKET; ROOT PLANING; SUBGINGIVAL CURETTAGE;

EID: 84870915764     PISSN: 01036440     EISSN: 18064760     Source Type: Journal    
DOI: 10.1590/S0103-64402012000400020     Document Type: Article

References (17)

1. Figueredo CM, Ribeiro MS, Fisher RG, Gustafsson A. Increased interleukin-1beta concentration in gingival crevicular fluid as a characteristic of periodontitis. J Periodontol 1999;70:1457-1463.
2. Engebretson S, Chertog R, Nichols A, Hey-hadavi J, Celenti R, Grbic J. Plasma levels of tumour necrosis factor-alpha in patients with chronic periodontitis and type 2 diabetes. J Clin Periodontol 2007;34:18-24.
3. Orozco A, Gemmell E, Bickel M, Seymour GJ. Interleukin-1b, Interleukin-12 and Interleukin-18 levels in gingival fluid and serum of patients with gingivitis and periodontitis. Oral Microbiol Immunol 2006;21:256-260.
4. Dinarello CA. IL-18: a T-inducing proinflammatory cytokine and new member of the IL-1 family. J Allergy Clin Immunol 1999;103:11-24.
5. Tanaka M, Harigai M, Kawaguchi Y, Ohta S, Sugiura T, Takagi K, et al. Mature form of interleukin-18 is expressed in rheumatoid arthritis synovial tissue and contributes to interferon-gamma production by synovial T cells. J Rheumatol 2001;28:1779-1787.
6. Hoshino T, Wiltrout RH, Young HA. IL-18 is a potent coinducer of IL-13 in NK and T cell: a new potential role for IL-18 in modulating the immune response. J Immunol 1999;162:5070-5077.
7. Kashiwamura S, Ueda H, Okamura H. Roles of interleukin-18 in tissue destruction and compensatory reaction. J Immunother 2002;25:4-11.
8. Johnson RB, Serio FG. Interleukin-18 concentrations and the pathogenesis of periodontal desease. J Periodontol 2005;76:785-790.
9. Pradeep AR, Daisy H, Hadge P, Garg G, Thorat M. Correlation of gingival crevicular fluid interleukin-18 and monocyte chemoattractant protein-1 levels in periodontal health and disease. J Periodontol 2009;80:1454-1461.
10. Ozcaka O, Nalbantsoy A, Buduneli N. Interleukin-17 and interleukin-18 levels in saliva and plasma of patients with chronic periodontitis. J Periodontol Res 2011;46:592-598.
11. Figueredo CM, Rescala B, Teles RP, Teles FP, Fischer RG, Haffajee AD, et al. Increased interleukin-18 in gingival crevicular fluid from periodontitis patients. Oral Microbiol Immunol 2008;23:173-176.
12. Silness J, Loë H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-131.
13. Loë H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38:610-616.
14. Salonen JI, Paunio KU. An intracrevicular washing method for collection of crevicular contents. Scand J Dent Res 1991;99:406-412.
15. Gamonal J, Acevedo A, Bascones A, Jorge O, Silva A. Levels of interleukin-1 beta, -8, and -10 and RANTES in gingival crevicular fluid and cell populations in adult periodontitis patients and the effect of periodontal treatment. J Periodontol 2000;71:1535-1545.
16. Goutoudi P, Diza E, Arvanitidou M. Effect of periodontal therapy on crevicular fluid interleukin-1beta and interleukin-10 levels in chronic periodontitis. J Dent 2004;32:511-520.
17. Badersten A, Nilvéus R, Egelberg J. Effect of non surgical periodontal therapy. VI. Localization of sites with probing attachment loss. J Clin Periodontol 1985;12:351-359.